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virF from Shigella sonnei Ss046

Victor ID 1634
Gene Name virF from Shigella sonnei Ss046
Sequence Strain (Species/Organism) Shigella sonnei Ss046
NCBI Gene ID 3671012
NCBI Protein GI 74314878
Locus Tag SSON_P041
Protein Accession YP_313296.1
Other Database IDs UniProtKB-ID: Q3YTV1_SHISS
UniRef100: UniRef100_P0A2T2
UniRef90: UniRef90_P0A2T2
UniRef50: UniRef50_P0A2T2
UniParc: UPI0000138851
EMBL: CP000039
EMBL-CDS: AAZ91061.1
RefSeq_NT: NC_007385.1
EnsemblGenome: EBESCG00000102071.
EnsemblGenome_TRS: EBESCT00000103027
EnsemblGenome_PRO: EBESCP00000098887
GenomeReviews: CP000039_GR
KEGG: ssn:SSON_P041
eggNOG: COG2207
HOGENOM: HBG674032
OMA: AVVEIEY
ProtClustDB: CLSK542186
BioCyc: SSON300269:SSO_P041-MONOMER
Taxonomy ID 300269
Plasmid No pSS_046
Gene Starting Position 37223
Gene Ending Position 38011
Gene Strand (Orientation) -
Protein Name member of the AraC family of transcriptional activators; required for transcription of virB and icsA
DNA Sequence 
>gi|74314838:37223-38011 Shigella sonnei Ss046 plasmid pSS_046, complete sequence
TTTAAAATTTTTTATGATATAAGTAAAATTTCTTTGGAGTTATACCATAATATTCATTAAATTTCCTTAT
AAAATAAGATGGGCTTGATATTCCGATAAGTCTTGATACATCATTAATATAGCTTTGACTATTCAATAAA
AGCTTTGCTGCATGATGCATGCGAATATCAAGAAGGATTTGTTGAAATGTTAATTTTTCACTCTCCAATC
GTTTTCTAACAGCTATTTCTGATAAATTCAAGTTATTTGAAATATCAGAAAGACGCCATCTCTTCTCGAT
GTTTTTTTCAACAATCTTCCTTATCTGATCAGAAAAACTAAGAGAAGAAGCTATCGATATCGAAGTATAT
AAAGCTTCCTCATCAGAAACAGCTGATAAAAGGCAAGCTAAACTATAGATCTTTCTTTTGCCGAAAGGCA
TCTCTTTTATAGATTTGAACAAATCGATAGAAACCTCCTCCTCAGAGAGGAGGAATATTTTTTTGTTTAA
CCCCCTTTTCTCCTCAGAATAGGAGTGTTGAAATGAATAAATTGGTTCCATTATTCTAATAATGCTTAAT
AATAAATTTCTGTCAAGGCTTATAATCTCAAATGGATTAATGCTATCAGATTTTTTTATGGAGACGTTTA
TTTGTATATTTCGCTCTATAAAAGCAATTTGCCCTTCATCGATAGTCAAAGTTTCATTGCCTGAGCTAAC
CGTCATTGAACACCTTTTTGCATATAAAATAATATAGTTATGCAAGCGAACCTTTATATCTATTTTGTTT
TTATGTCCCATATCCATCA
Protein Sequence 
>gi|74314878|ref|YP_313296.1| VirF [Shigella sonnei Ss046] MMDMGHKNKIDIKVRLHNYIILYAKRCSMTVSSGNETLTIDEGQIAFIERNIQINVSIKKSDSINPFEIISLDRNLLLSIIRIMEPIYSFQHSYSEEKRGLNKKIFLLSEEEVSIDLFKSIKEMPFGKRKIYSLACLLSAVSDEEALYTSISIASSLSFSDQIRKIVEKNIEKRWRLSDISNNLNLSEIAVRKRLESEKLTFQQILLDIRMHHAAKLLLNSQSYINDVSRLIGISSPSYFIRKFNEYYGITPKKFYLYHKKF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: virF knockouts are non-invasive to host cells (Hurt et al., 2010).
COG COG2207K, under K: Transcription
References
Hurt et al., 2010: Hurt JK, McQuade TJ, Emanuele A, Larsen MJ, Garcia GA. High-throughput screening of the virulence regulator VirF: a novel antibacterial target for shigellosis. Journal of biomolecular screening : the official journal of the Society for Biomolecular Screening. 2010; 15(4); 379-387. [PubMed: 20237205].