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ipgB2 from Shigella sonnei Ss046

Victor ID 1633
Gene Name ipgB2 from Shigella sonnei Ss046
Sequence Strain (Species/Organism) Shigella sonnei Ss046
NCBI Gene ID 3670995
NCBI Protein GI 74314861
Locus Tag SSON_P024
Protein Accession YP_313279.1
Other Database IDs UniProtKB-ID: Q3YTW8_SHISS
UniRef100: UniRef100_Q3YTW8
UniRef90: UniRef90_Q327H0
UniRef50: UniRef50_Q327H0
UniParc: UPI00005AACD3
EMBL: CP000039
EMBL-CDS: AAZ91044.1
RefSeq_NT: NC_007385.1
EnsemblGenome: EBESCG00000102138.
EnsemblGenome_TRS: EBESCT00000103094
EnsemblGenome_PRO: EBESCP00000098954
GenomeReviews: CP000039_GR
KEGG: ssn:SSON_P024
HOGENOM: HBG683966
OMA: RISLDIN
ProtClustDB: CLSK540077
BioCyc: SSON300269:SSO_P024-MONOMER
Taxonomy ID 300269
Plasmid No pSS_046
Gene Starting Position 18739
Gene Ending Position 19305
Gene Strand (Orientation) +
Protein Name probably secreted by the Mxi-Spa secretion machinery
DNA Sequence 
>gi|74314838:18739-19305 Shigella sonnei Ss046 plasmid pSS_046, complete sequence
AATGCTTGGAACATCTTTTAATAATTTTGGAATCAGTTTATCTCACAAAAGATATTTTTCAGGAAAGGTG
GATGAGATTATCCGCTGTACAATGGGGAAAAGGATAGTAAAAATATCATCAACCAAAATAAATACTAGTA
TTTTGAGCTCTGTTTCAGAACAAATCGGTGAAAATATTACAGATTGGAAAAATGATGAAAAAAAAGTCTA
CGTATCCCGGGTGGTAAACCAATGTATTGATAAGTTTTGTGCAGAACACAGCCGAGAAATCGGCGATAAC
CTCCGTAAACAGATATTTAAACAGGTTGAGAAAGATTATCGCATTTCTCTAGACATCAATGCTGCACAAA
GTTCCATAAATCATCTTGTATCAGGAAGCAGTTATTTCAAAAAGAAAATGGACGAACTTTGTGAAGGGAT
GAATAGAAGCGTTAAAAATGATACAACAAGCAATGTTGCAAATCTTATTTCCGATCAGTTTTTTGAGAAA
AATGTGCAATATATTGATCTAAAGAAATTACGTGGGAATATGAGTGACTATATTACAAATTTAGAATCGC
CTTTCTG
Protein Sequence 
>gi|74314861|ref|YP_313279.1| IpgB2 [Shigella sonnei Ss046] MLGTSFNNFGISLSHKRYFSGKVDEIIRCTMGKRIVKISSTKINTSILSSVSEQIGENITDWKNDEKKVYVSRVVNQCIDKFCAEHSREIGDNLRKQIFKQVEKDYRISLDINAAQSSINHLVSGSSYFKKKMDELCEGMNRSVKNDTTSNVANLISDQFFEKNVQYIDLKKLRGNMSDYITNLESPF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: ipgB2 mutant had entry into polarized cells reduced by 70% compared to the wild-type (Hachani et al., 2008).
References
Hachani et al., 2008: Hachani A, Biskri L, Rossi G, Marty A, Ménard R, Sansonetti P, Parsot C, Van Nhieu GT, Bernardini ML, Allaoui A. IpgB1 and IpgB2, two homologous effectors secreted via the Mxi-Spa type III secretion apparatus, cooperate to mediate polarized cell invasion and inflammatory potential of Shigella flexenri. Microbes and infection / Institut Pasteur. 2008; 10(3); 260-268. [PubMed: 18316224].