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spa33 from Shigella sonnei Ss046

Victor ID 1628
Gene Name spa33 from Shigella sonnei Ss046
Sequence Strain (Species/Organism) Shigella sonnei Ss046
NCBI Gene ID 3670858
NCBI Protein GI 74314951
Locus Tag SSON_P114
Protein Accession YP_313369.1
Other Database IDs UniProtKB-ID: Q3YTM8_SHISS
UniRef100: UniRef100_P0A1K9
UniRef90: UniRef90_P0A1K9
UniRef50: UniRef50_P0A1K9
UniParc: UPI0000135DA0
EMBL: CP000039
EMBL-CDS: AAZ91134.1
RefSeq_NT: NC_007385.1
EnsemblGenome: EBESCG00000102018.
EnsemblGenome_TRS: EBESCT00000102974
EnsemblGenome_PRO: EBESCP00000098834
GenomeReviews: CP000039_GR
KEGG: ssn:SSON_P114
eggNOG: COG1886
HOGENOM: HBG683580
OMA: FRITNEI
ProtClustDB: CLSK505063
BioCyc: SSON300269:SSO_P114-MONOMER
Taxonomy ID 300269
Plasmid No pSS_046
Gene Starting Position 105029
Gene Ending Position 105910
Gene Strand (Orientation) +
Protein Name component of the Mxi-Spa secretion machinery
DNA Sequence 
>gi|74314838:105029-105910 Shigella sonnei Ss046 plasmid pSS_046, complete sequence
AATGCTAAGAATTAAACATTTTGACGCTAACGAAAAACTACAGATTTTATATGCAAAGCAACTCTGCGAG
CGTTTTTCGATTCAGACATTCAAAAATAAATTTACAGGCAGTGAAAGTTTAGTCACTCTTACTTCCGTGT
GTGGGGATTGGGTAATTCGTATTGATACATTATCTTTTTTGAAAAAAAAATACGAGGTATTTTCAGGATT
TTCTACACAAGAATCTTTACTGCATTTATCAAAATGTGTCTTTATAGAGTCGTCATCTGTATTTTCGATT
CCAGAACTGTCTGATAAGATTACTTTCCGGATCACGAATGAAATCCAGTATGCAACTACTGGGAGTCATT
TATGCTGTTTTTCCTCTTCTTTAGGTATTATTTATTTTGACAAGATGCCGGTATTACGTAATCAAGTTTC
TCTTGACTTATTGCATCATCTTTTAGAGTTTTGCTTAGGTTCATCTAATGTAAGGCTGGCTACTTTAAAA
AGAATTCGCACTGGTGATATAATCATAGTTCAGAAACTTTATAATTTATTATTGTGTAATCAAGTTATTA
TTGGGGATTATATTGTGAATGATAATAATGAGGCAAAAATTAATCTGTCAGAAAGTAATGGTGAGTCAGA
ACACACAGAAGTTTCTTTGGCATTATTCAATTATGATGATATCAATGTAAAAGTGGACTTTATTCTTTTA
GAAAAAAATATGACAATCAATGAACTAAAAATGTATGTAGAAAACGAATTATTCAAGTTTCCCGATGACA
TAGTTAAACATGTAAATATTAAAGTAAATGGTTCTTTGGTTGGGCATGGGGAACTTGTTTCTATTGAGGA
TGGTTATGGTATCGAGATTAGTTCTTGGATGGTAAAGGAGTA
Protein Sequence 
>gi|74314951|ref|YP_313369.1| Spa33 [Shigella sonnei Ss046] MLRIKHFDANEKLQILYAKQLCERFSIQTFKNKFTGSESLVTLTSVCGDWVIRIDTLSFLKKKYEVFSGFSTQESLLHLSKCVFIESSSVFSIPELSDKITFRITNEIQYATTGSHLCCFSSSLGIIYFDKMPVLRNQVSLDLLHHLLEFCLGSSNVRLATLKRIRTGDIIIVQKLYNLLLCNQVIIGDYIVNDNNEAKINLSESNGESEHTEVSLALFNYDDINVKVDFILLEKNMTINELKMYVENELFKFPDDIVKHVNIKVNGSLVGHGELVSIEDGYGIEISSWMVKE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: spa33 mutants are unable to secrete effectors necessary to cell invasion (Morita-Ishihara et al., 2006).
COG COG1886NU, under N: Cell motility; U: Intracellular trafficking, secretion, and vesicular transport
References
Morita-Ishihara et al., 2006: Morita-Ishihara T, Ogawa M, Sagara H, Yoshida M, Katayama E, Sasakawa C. Shigella Spa33 is an essential C-ring component of type III secretion machinery. The Journal of biological chemistry. 2006; 281(1); 599-607. [PubMed: 16246841].