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spa32 from Shigella sonnei Ss046

Victor ID 1627
Gene Name spa32 from Shigella sonnei Ss046
Sequence Strain (Species/Organism) Shigella sonnei Ss046
NCBI Gene ID 3670857
NCBI Protein GI 74314950
Locus Tag SSON_P113
Protein Accession YP_313368.1
Other Database IDs UniProtKB-ID: Q3YTM9_SHISS
UniRef100: UniRef100_P0A1K5
UniRef90: UniRef90_P0A1K5
UniRef50: UniRef50_P0A1K5
UniParc: UPI0000135D9E
EMBL: CP000039
EMBL-CDS: AAZ91133.1
RefSeq_NT: NC_007385.1
EnsemblGenome: EBESCG00000102119.
EnsemblGenome_TRS: EBESCT00000103075
EnsemblGenome_PRO: EBESCP00000098935
GenomeReviews: CP000039_GR
KEGG: ssn:SSON_P113
HOGENOM: HBG210275
OMA: HTSSANP
ProtClustDB: CLSK505062
BioCyc: SSON300269:SSO_P113-MONOMER
Taxonomy ID 300269
Plasmid No pSS_046
Gene Starting Position 104157
Gene Ending Position 105035
Gene Strand (Orientation) +
Protein Name secreted by and component of the Mxi-Spa machinery
DNA Sequence 
>gi|74314838:104157-105035 Shigella sonnei Ss046 plasmid pSS_046, complete sequence
TATGGCATTAGATAATATAAACCTAAATTTTAGTAGTGACAAACAGATAGAAAAATGTGAGAAACTATCT
TCAATAGATAATATTGATAGTCTCGTTTTGAAGAAGAAGAGGAAGGTTGAAATTCCTGAGTACTCTTTAA
TTGCATCTAACTATTTTACTATTGATAAGCACTTTGAACATAAGCATGATAAAGGAGAAATTTATAGTGG
CATTAAAAATGCGTTCGAACTTAGAAACGAACGAGCGACATATTCTGATATTCCAGAATCAATGGCCATT
AAAGAAAATATTTTGATACCAGATCAAGATATAAAAGCAAGGGAAAAAATAAATATCGGCGATATGAGGG
GGATCTTTTCATATAATAAGAGTGGAAATGCAGACAAGAACTTCGAAAGAAGTCATACTTCTTCTGTAAA
CCCTGATAATCTGCTAGAATCTGATAATAGAAATGGTCAAATTGGTTTAAAAAATCATAGCTTGTCTATT
GATAAGAATATTGCTGACATCATTTCTTTACTAAATGGAAGTGTTGCTAAATCATTTGAGCTGCCTGTAA
TGAATAAAAATACTGCAGACATAACCCCATCCATGTCATTGCAAGAAAAATCAATAGTTGAAAATGATAA
AAATGTTTTTCAAAAAAATAGTGAAATGACTTACCACTTTAAACAGTGGGGGGCTGGACATTCTGTTAGT
ATTTCAGTGGAGTCTGGTTCTTTTGTTCTAAAACCGTCAGATCAATTTGTAGGAAATAAACTTGACTTAA
TTTTGAAACAAGATGCTGAGGGTAATTATAGATTTGATAGCAGTCAACATAATAAGGGGAATAAAAATAA
TAGTACAGGATATAATGAACAGAGTGAAGAAGAATGCTA
Protein Sequence 
>gi|74314950|ref|YP_313368.1| Spa32 [Shigella sonnei Ss046] MALDNINLNFSSDKQIEKCEKLSSIDNIDSLVLKKKRKVEIPEYSLIASNYFTIDKHFEHKHDKGEIYSGIKNAFELRNERATYSDIPESMAIKENILIPDQDIKAREKINIGDMRGIFSYNKSGNADKNFERSHTSSVNPDNLLESDNRNGQIGLKNHSLSIDKNIADIISLLNGSVAKSFELPVMNKNTADITPSMSLQEKSIVENDKNVFQKNSEMTYHFKQWGAGHSVSISVESGSFVLKPSDQFVGNKLDLILKQDAEGNYRFDSSQHNKGNKNNSTGYNEQSEEEC
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: spa32 mutants are unable to invade HeLa cells and do not secrete type III effectors (Tamano et al., 2002).
References
Tamano et al., 2002: Tamano K, Katayama E, Toyotome T, Sasakawa C. Shigella Spa32 is an essential secretory protein for functional type III secretion machinery and uniformity of its needle length. Journal of bacteriology. 2002; 184(5); 1244-1252. [PubMed: 11844752].