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mxiD from Shigella sonnei Ss046

Victor ID 1622
Gene Name mxiD from Shigella sonnei Ss046
Sequence Strain (Species/Organism) Shigella sonnei Ss046
NCBI Gene ID 3670851
NCBI Protein GI 74314944
Locus Tag SSON_P107
Protein Accession YP_313362.1
Other Database IDs UniProtKB-ID: Q3YTN5_SHISS
UniRef100: UniRef100_Q3YTN5
UniRef90: UniRef90_Q04641
UniRef50: UniRef50_Q04641
UniParc: UPI00005AAD00
EMBL: CP000039
EMBL-CDS: AAZ91127.1
RefSeq_NT: NC_007385.1
EnsemblGenome: EBESCG00000102085.
EnsemblGenome_TRS: EBESCT00000103041
EnsemblGenome_PRO: EBESCP00000098901
GenomeReviews: CP000039_GR
KEGG: ssn:SSON_P107
eggNOG: COG1450
HOGENOM: HBG640696
OMA: VFLIQPR
ProtClustDB: CLSK862854
BioCyc: SSON300269:SSO_P107-MONOMER
Taxonomy ID 300269
Plasmid No pSS_046
Gene Starting Position 97170
Gene Ending Position 98870
Gene Strand (Orientation) +
Protein Name outermembrane protein of the secretin family; component of the Mxi-Spa secretion machinery
DNA Sequence 
>gi|74314838:97170-98870 Shigella sonnei Ss046 plasmid pSS_046, complete sequence
AATGAAAAAATTTAATATTAAATCTTTGACTCTCTTGATTGTATTGTTACCATTGATAGTTAATGCTAAT
AATATTGACTCTCATTTATTAGAACAAAATGACATAGCGAAATATGTTGCTCAAAGTGATACGGTAGGAT
CTTTTTTTGAACGTTTTTCTGCGTTATTAAATTATCCTATTGTTGTTAGCAAACAAGCTGCAAAAAAGAG
AATATCTGGGGAGTTTGATTTATCTAATCCAGAAGAAATGCTTGAAAAACTGACATTACTTGTGGGACTC
ATATGGTATAAAGATGGAAATGCATTATACATATATGACTCTGGAGAATTAATAAGCAAAGTTATTTTGC
TGGAGAATATATCACTTAATTATCTTATTCAGTATCTGAAGGATGCTAACCTTTATGATCACAGATATCC
TATAAGAGGAAATATTAGTGATAAAACATTCTATATATCTGGTCCTCCGGCATTGGTTGAACTGGTAGCT
AATACAGCAACTTTGCTTGATAAGCAGGTTTCTTCTATTGGGACAGATAAAGTTAATTTTGGGGTTATAA
AATTAAAAAATACATTTGTTAGTGACAGAACTTATAATATGAGAGGGGAGGATATTGTCATCCCAGGGGT
GGCTACTGTTGTAGAACGTTTATTAAATAATGGTAAGGCTCTGAGTAACAGACAAGCCCAAAATGATCCG
ATGCCACCCTTTAATATTACACAGAAAGTATCTGAGGATAGTAATGACTTTTCATTTAGTTCAGTTACCA
ATAGTTCTATATTAGAGGATGTATCACTTATTGCATATCCAGAAACCAATTCTATATTAGTCAAAGGTAA
TGATCAGCAAATACAGATTATTCGCGATATTATCACTCAGTTAGATGTAGCCAAACGACATATAGAATTA
TCATTATGGATAATCGATATTGATAAATCTGAATTAAATAACCTTGGTGTTAATTGGCAAGGAACGGCTT
CATTTGGTGATTCGTTTGGTGCGTCATTTAATATGAGCTCATCAGCATCGATAAGCACTTTGGACGGCAA
TAAGTTTATTGCTTCAGTTATGGCATTAAATCAGAAAAAGAAAGCAAATGTAGTTTCAAGGCCGGTGATT
TTGACACAAGAGAATATTCCGGCTATATTTGATAATAACAGGACTTTTTATGTGTCATTAGTTGGTGAGC
GCAATTCTTCGTTGGAGCATGTTACGTATGGAACATTGATAAATGTTATACCTCGCTTTTCATCTCGGGG
ACAAATTGAGATGTCTTTAACGATAGAGGATGGAACAGGAAATAGTCAGTCAAATTACAATTATAATAAT
GAAAATACATCTGTCCTTCCAGAAGTTGGAAGGACCAAAATCAGTACAATAGCGAGAGTTCCACAAGGCA
AAAGTTTGTTGATAGGTGGTTATACGCATGAAACGAACTCTAACGAAATAGTATCTATTCCTTTTCTCTC
CTCTATTCCTGTAATCGGTAATGTGTTCAAGTATAAAACAAGTAATATCAGTAATATTGTAAGGGTTTTT
CTGATTCAACCCCGTGAGATAAAGGAGTCAAGTTATTATAATACTGCAGAATATAAAAGCCTCATATCTG
AAAGAGAAATACAAAAGACTACACAAATAATCCCATCTGAAACTACTTTGCTGGAAGACGAAAAATCATT
GGTTTCATACTTAAATTACTA
Protein Sequence 
>gi|74314944|ref|YP_313362.1| MxiD [Shigella sonnei Ss046] MKKFNIKSLTLLIVLLPLIVNANNIDSHLLEQNDIAKYVAQSDTVGSFFERFSALLNYPIVVSKQAAKKRISGEFDLSNPEEMLEKLTLLVGLIWYKDGNALYIYDSGELISKVILLENISLNYLIQYLKDANLYDHRYPIRGNISDKTFYISGPPALVELVANTATLLDKQVSSIGTDKVNFGVIKLKNTFVSDRTYNMRGEDIVIPGVATVVERLLNNGKALSNRQAQNDPMPPFNITQKVSEDSNDFSFSSVTNSSILEDVSLIAYPETNSILVKGNDQQIQIIRDIITQLDVAKRHIELSLWIIDIDKSELNNLGVNWQGTASFGDSFGASFNMSSSASISTLDGNKFIASVMALNQKKKANVVSRPVILTQENIPAIFDNNRTFYVSLVGERNSSLEHVTYGTLINVIPRFSSRGQIEMSLTIEDGTGNSQSNYNYNNENTSVLPEVGRTKISTIARVPQGKSLLIGGYTHETNSNEIVSIPFLSSIPVIGNVFKYKTSNISNIVRVFLIQPREIKESSYYNTAEYKSLISEREIQKTTQIIPSETTLLEDEKSLVSYLNY
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: mxiD mutant is unable to invade HeLa cells or to provoke keratoconjunctivitis in guinea-pigs (Allaoui et al., 1993).
COG COG1450NU, under N: Cell motility; U: Intracellular trafficking, secretion, and vesicular transport
References
Allaoui et al., 1993: Allaoui A, Sansonetti PJ, Parsot C. MxiD, an outer membrane protein necessary for the secretion of the Shigella flexneri lpa invasins. Molecular microbiology. 1993; 7(1); 59-68. [PubMed: 8437520].