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Rv3866

Victor ID 162
Gene Name Rv3866
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 886200
NCBI Protein GI 15611002
Locus Tag Rv3866
Protein Accession NP_218383.1
Other Database IDs UniProtKB-ID: ESPG1_MYCTU
UniRef100: UniRef100_P96210
UniRef90: UniRef90_P96210
UniRef50: UniRef50_P96210
UniParc: UPI00000C155A
EMBL: BX842584
EMBL-CDS: CAB06238.1
RefSeq_NT: NC_000962.2
EnsemblGenome: EBMYCG00000000854
EnsemblGenome_TRS: EBMYCT00000000854
EnsemblGenome_PRO: EBMYCP00000000854
GenomeReviews: AL123456_GR
KEGG: mtu:Rv3866
TubercuList: Rv3866
HOGENOM: HBG568434
OMA: CRWWRRD
ProtClustDB: CLSK792771
Taxonomy ID 83332
Gene Starting Position 4341879
Gene Ending Position 4342730
Gene Strand (Orientation) +
Protein Name hypothetical protein
DNA Sequence 
>gi|57116681:4341879-4342730 Mycobacterium tuberculosis H37Rv, complete genome
CATGACGGGTCCGTCCGCTGCAGGCCGCGCGGGCACCGCCGACAACGTGGTCGGCGTCGAGGTAACCATC
GACGGCATGTTGGTGATCGCCGATCGGTTACACCTGGTTGATTTCCCTGTCACGCTTGGGATTCGGCCGA
ATATCCCGCAAGAGGATCTGCGAGACATCGTCTGGGAACAGGTGCAGCGTGACCTCACAGCGCAAGGGGT
GCTCGACCTCCACGGGGAGCCCCAACCGACGGTCGCGGAGATGGTCGAAACCCTGGGCAGGCCAGATCGG
ACCTTGGAGGGTCGCTGGTGGCGGCGCGACATTGGCGGCGTCATGGTGCGCTTCGTCGTGTGCCGCAGGG
GCGACCGCCATGTGATCGCGGCGCGCGACGGCGACATGCTGGTGCTGCAGTTGGTGGCGCCGCAGGTCGG
CTTGGCGGGCATGGTGACAGCGGTGCTGGGGCCCGCCGAACCCGCCAACGTCGAACCCCTGACGGGTGTG
GCAACCGAGCTAGCCGAATGCACAACCGCGTCCCAATTGACGCAATACGGTATCGCACCGGCCTCGGCCC
GCGTCTATGCCGAGATCGTGGGTAACCCGACCGGCTGGGTGGAGATCGTTGCCAGCCAACGCCACCCCGG
CGGCACCACGACGCAGACCGACGCCGCCGCTGGCGTCCTGGACTCCAAGCTCGGTAGGCTGGTGTCGCTT
CCCCGCCGTGTTGGAGGCGACCTGTACGGAAGCTTCCTGCCCGGCACTCAGCAGAACTTGGAGCGTGCGC
TGGACGGCTTGCTAGAGCTGCTCCCTGCGGGCGCTTGGCTAGATCACACCTCAGATCACGCACAAGCCTC
CTCCCGAGGCTG
Protein Sequence 
>gi|15611002|ref|NP_218383.1| ESX-1 secretion-associated protein EspG [Mycobacterium tuberculosis H37Rv] MTGPSAAGRAGTADNVVGVEVTIDGMLVIADRLHLVDFPVTLGIRPNIPQEDLRDIVWEQVQRDLTAQGVLDLHGEPQPTVAEMVETLGRPDRTLEGRWWRRDIGGVMVRFVVCRRGDRHVIAARDGDMLVLQLVAPQVGLAGMVTAVLGPAEPANVEPLTGVATELAECTTASQLTQYGIAPASARVYAEIVGNPTGWVEIVASQRHPGGTTTQTDAAAGVLDSKLGRLVSLPRRVGGDLYGSFLPGTQQNLERALDGLLELLPAGAWLDHTSDHAQASSRG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: Rv3866 mutant is attenuated in mice (Brodin et al., 2006).
References
Brodin et al., 2006: Brodin P, Majlessi L, Marsollier L, de Jonge MI, Bottai D, Demangel C, Hinds J, Neyrolles O, Butcher PD, Leclerc C, Cole ST, Brosch R. Dissection of ESAT-6 system 1 of Mycobacterium tuberculosis and impact on immunogenicity and virulence. Infection and immunity. 2006; 74(1); 88-98. [PubMed: 16368961].