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mxiJ from Shigella sonnei Ss046

Victor ID 1617
Gene Name mxiJ from Shigella sonnei Ss046
Sequence Strain (Species/Organism) Shigella sonnei Ss046
NCBI Gene ID 3670845
NCBI Protein GI 74314938
Locus Tag SSON_P101
Protein Accession YP_313356.1
Other Database IDs UniProtKB-ID: Q3YTP1_SHISS
UniRef100: UniRef100_Q55288
UniRef90: UniRef90_Q06081
UniRef50: UniRef50_Q06081
UniParc: UPI000012FAB3
EMBL: CP000039
EMBL-CDS: AAZ91121.1
RefSeq_NT: NC_007385.1
EnsemblGenome: EBESCG00000102036.
EnsemblGenome_TRS: EBESCT00000102992
EnsemblGenome_PRO: EBESCP00000098852
GenomeReviews: CP000039_GR
KEGG: ssn:SSON_P101
eggNOG: COG4669
HOGENOM: HBG671305
OMA: HISVIAI
ProtClustDB: CLSK2392807
BioCyc: SSON300269:SSO_P101-MONOMER
Taxonomy ID 300269
Plasmid No pSS_046
Gene Starting Position 93723
Gene Ending Position 94448
Gene Strand (Orientation) +
Protein Name lipoprotein, component of the Mxi-Spa secretion machinery
DNA Sequence 
>gi|74314838:93723-94448 Shigella sonnei Ss046 plasmid pSS_046, complete sequence
TATGATTAGGTATAAAGGTTTTATTTTATTCTTGTTGCTGATGTTGATTGGATGTGAGCAACGTGAAGAG
TTAATTTCTAATTTATCTCAAAGACAGGCAAATGAAATAATATCTGTGCTAGAACGCCATAATATTACTG
CTAGAAAAGTTGATGGAGGTAAACAGGGGATCTCGGTACAAGTCGAAAAGGGGACATTTGCATCGGCAGT
TGATTTGATGCGCATGTACGATTTGCCAAATCCGGAGAGAGTTGATATCTCACAAATGTTTCCTACAGAT
TCATTAGTGTCTTCTCCAAGAGCTGAAAAGGCCCGTTTATATAGTGCTATTGAGCAACGGCTGGAACAGT
CTTTAGTTTCTATTGGTGGTGTTATTTCGGCAAAAATACATGTTAGCTATGATCTTGAAGAAAAAAATAT
ATCTTCAAAACCGATGCATATATCAGTAATCGCTATATATGACTCACCGAAAGAGTCTGAACTATTAGTT
AGTAATATTAAGCGATTTTTGAAAAACACCTTTTCTGATGTTAAGTATGAAAATATATCTGTCATATTAA
CTCCGAAAGAAGAATATGTTTATACAAATGTACAACCTGTTAAGGAAATTAAATCGGAATTTTTAACAAA
TGAAGTAATATATTTATTTCTCGGGATGGCTGTACTAGTTGTCATTCTTTTGGTATGGGCATTCAAAACA
GGGTGGTTCAAGAGAAACAAAATATG
Protein Sequence 
>gi|74314938|ref|YP_313356.1| MxiJ [Shigella sonnei Ss046] MIRYKGFILFLLLMLIGCEQREELISNLSQRQANEIISVLERHNITARKVDGGKQGISVQVEKGTFASAVDLMRMYDLPNPERVDISQMFPTDSLVSSPRAEKARLYSAIEQRLEQSLVSIGGVISAKIHVSYDLEEKNISSKPMHISVIAIYDSPKESELLVSNIKRFLKNTFSDVKYENISVILTPKEEYVYTNVQPVKEIKSEFLTNEVIYLFLGMAVLVVILLVWAFKTGWFKRNKI
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: mxiJ mutant was unable to invade HeLa cells, to induce the formation of plaques on confluent monolayers of HeLa cells, and to provoke keratoconjunctivitis in guinea pigs (Allaoui et al., 1992).
COG COG4669U, under U: Intracellular trafficking, secretion, and vesicular transport
References
Allaoui et al., 1992: Allaoui A, Sansonetti PJ, Parsot C. MxiJ, a lipoprotein involved in secretion of Shigella Ipa invasins, is homologous to YscJ, a secretion factor of the Yersinia Yop proteins. Journal of bacteriology. 1992; 174(23); 7661-7669. [PubMed: 1332940].