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icsB from Shigella sonnei Ss046

Victor ID 1612
Gene Name icsB from Shigella sonnei Ss046
Sequence Strain (Species/Organism) Shigella sonnei Ss046
NCBI Gene ID 3670838
NCBI Protein GI 74314931
Locus Tag SSON_P094
Protein Accession YP_313349.1
Other Database IDs UniProtKB-ID: Q3YTP8_SHISS
UniRef100: UniRef100_Q3YTP8
UniRef90: UniRef90_P33546
UniRef50: UniRef50_P33546
UniParc: UPI00005AACFF
EMBL: CP000039
EMBL-CDS: AAZ91114.1
RefSeq_NT: NC_007385.1
EnsemblGenome: EBESCG00000102038.
EnsemblGenome_TRS: EBESCT00000102994
EnsemblGenome_PRO: EBESCP00000098854
GenomeReviews: CP000039_GR
KEGG: ssn:SSON_P094
eggNOG: NOG147445
HOGENOM: HBG683611
OMA: KSENCAG
ProtClustDB: CLSK688131
BioCyc: SSON300269:SSO_P094-MONOMER
Taxonomy ID 300269
Plasmid No pSS_046
Gene Starting Position 87784
Gene Ending Position 89268
Gene Strand (Orientation) -
Protein Name invasion protein
DNA Sequence 
>gi|74314838:87784-89268 Shigella sonnei Ss046 plasmid pSS_046, complete sequence
TCTATATATTAGAATGAGAGTTATTCAATAAAAGCTTATTGACCTGTAATAAGTCGTGAATGTAAAGTTT
GGTTCCAAGATCTGGCGATTTAAGAGAATTGTAATAATCAATAGTTTTTATTGACTTTTCGATAATTTCT
TCTTTTTTATCTGTTGCTCCGGTTTTTAATTCGTTTAATACACGAGACATATTGCTGGGTGCTGATTTTA
CTAAGTATGAGTGGCAAGCGTTGATGACCGCATCAAAGTCTTCTGAAGATACATTTTCAGTAGGATGTTT
GTAAAGTGAAATTGATAAAGGCTTGAATGTTTTTGGGGTGTGGATAAGGTTAATTTTATTGAAACTTTTA
AGATAGCTACGTCGTAATTGAGTCAATCTGGAAAGATCAAAATCAGATTCAATATACTTCATTATCTCGT
TATAAGACTGATTGAGACTTTCAATGCGTTGCCTAACTTTATTTGCATACGCGTATACATTGTTAGGTGT
AGCAACCAATTTAACGTCAGGGAGTGGAAAGTATATTTCAGAATTTCCTGCTTTAAGAACATTAAGTGCC
ATACCAGCACAGTTTTCAGATTTACTGATTAATTTATAATTTGCCAATTGTCTGAAAGCATCTGCTTTCT
TTTGGCATATAAATTTTGACATGTTTGTTTCATCAAGGCCAAAAAGGTTATAGCTGATTTTACCATCCTT
TGTTTTATTATCACCTGATAATGGAATGTATACTTTATCAGCACTGACCCCCCAATAACCATAGGGGTCT
TTTTTTTGATTAGCTCTGGGAAAAAATATTTTTTTGTTGTTATTTTGATCTTGTTTTGAATTTAATAAGT
TTCTAACCTCTTGGCCTGCATCAAGTCTTTCGGCTGTTTGGTCTGAAATCATATTTAGTTTGTCTTGTTT
ATAGGTATCGACACTGTAACCTGAGCGTTTTTCAAAAAGGTAGTTTATTTCTGTATCTTTTGTAACATTC
CCGCCGGGATACCAGCTGAGATAGGTATGAGTTGGTTCCTGTAGTAAATTGTTTTTTATACTGATACTGG
TATGCCCTAAATGGGTTATGCCTCTATTTCCCCAGCAACGAAAAACTAAATGTCTTTCAAGATTTTTGGC
TGTACCGATGCCATGAAAACGCTCTGCGGTATTCAACATTAATTTGATGTCTTTACCTGTAAAAGAATGT
TGAATTGAATTTTTGACTGCTTCATAGGCGGCAAACGCACTTTCTGCAGATTTTTCGCTAGCTAATGTCT
TGAGGAAAAGCAATAAGGATTTTTGATTCGCTAGTCGATAATTTTTTAGTTGTTCATTTAATATCTGTGA
ATTTATCTTTGCATTAATAGTGCTTAATGTTCTGAAAAAGAGATCCTTTAGGTTGAATTTCTGTGCTACC
AATATAGGTCCATGCTCTGTATCTTCAACGCGTATAGGCCCTTTTGTATTGCTTGCGTCAATGAAATTGC
TAATTTTGAGGATCA
Protein Sequence 
>gi|74314931|ref|YP_313349.1| IcsB [Shigella sonnei Ss046] MILKISNFIDASNTKGPIRVEDTEHGPILVAQKFNLKDLFFRTLSTINAKINSQILNEQLKNYRLANQKSLLLFLKTLASEKSAESAFAAYEAVKNSIQHSFTGKDIKLMLNTAERFHGIGTAKNLERHLVFRCWGNRGITHLGHTSISIKNNLLQEPTHTYLSWYPGGNVTKDTEINYLFEKRSGYSVDTYKQDKLNMISDQTAERLDAGQEVRNLLNSKQDQNNNKKIFFPRANQKKDPYGYWGVSADKVYIPLSGDNKTKDGKISYNLFGLDETNMSKFICQKKADAFRQLANYKLISKSENCAGMALNVLKAGNSEIYFPLPDVKLVATPNNVYAYANKVRQRIESLNQSYNEIMKYIESDFDLSRLTQLRRSYLKSFNKINLIHTPKTFKPLSISLYKHPTENVSSEDFDAVINACHSYLVKSAPSNMSRVLNELKTGATDKKEEIIEKSIKTIDYYNSLKSPDLGTKLYIHDLLQVNKLLLNNSHSNI
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: icsB mutants are attenuated in guinea pig eyes (Ogawa et al., 2003).
References
Ogawa et al., 2003: Ogawa M, Suzuki T, Tatsuno I, Abe H, Sasakawa C. IcsB, secreted via the type III secretion system, is chaperoned by IpgA and required at the post-invasion stage of Shigella pathogenicity. Molecular microbiology. 2003; 48(4); 913-931. [PubMed: 12753186].