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ipgB1 from Shigella sonnei Ss046

Victor ID 1610
Gene Name ipgB1 from Shigella sonnei Ss046
Sequence Strain (Species/Organism) Shigella sonnei Ss046
NCBI Gene ID 3670836
NCBI Protein GI 74314929
Locus Tag SSON_P092
Protein Accession YP_313347.1
Other Database IDs UniProtKB-ID: Q3YTQ0_SHISS
UniRef100: UniRef100_Q3YTQ0
UniRef90: UniRef90_P33548
UniRef50: UniRef50_P33548
UniParc: UPI00005AACFE
EMBL: CP000039
EMBL-CDS: AAZ91112.1
RefSeq_NT: NC_007385.1
EnsemblGenome: EBESCG00000102178.
EnsemblGenome_TRS: EBESCT00000103134
EnsemblGenome_PRO: EBESCP00000098994
GenomeReviews: CP000039_GR
KEGG: ssn:SSON_P092
HOGENOM: HBG683610
OMA: IDEMAIH
ProtClustDB: CLSK505042
BioCyc: SSON300269:SSO_P092-MONOMER
Taxonomy ID 300269
Plasmid No pSS_046
Gene Starting Position 86740
Gene Ending Position 87366
Gene Strand (Orientation) -
Protein Name secreted by the Mxi-Spa machinery
DNA Sequence 
>gi|74314838:86740-87366 Shigella sonnei Ss046 plasmid pSS_046, complete sequence
TTTAATTTGTATTGCTTTGACGGTATACGGCCTTTAGAACCTCTGCGCTTATTTCTATTTGTAAAACTTT
TGTTGATTCATTAAATATTTTATCGTAGACGGAACTGGATACTAGATTTGTAAGATCCTTCATTTGTGTG
TTAAACAAATCCATGTTACTGCTATAGCGTTTTAAAATCTTTGCTCTGAGGCCAGATGAGGCAATCTCGT
TTAGTGCTGTATGACTGATAGATGTTTGTGCTGATTTTTCATCAAGTTTTATATCCGGGAATTTTTTTTC
AATAGCTGCAAATATGTTTTTTTTGTTATCTGAGGTCAAAACAACTCCATTGTGTATGGCCATTTCATCT
ATACTTCTGTTTATCATTGAAGAGACATAAGAGGTTCGCTCTTGGCTCATCCAACAAAATAGTTGATTCC
CCGAATTACTATCTTTTATTTTGTCTATGACGTTGTCCCTGATTTTATTTATATTCACCGGGCATCCAAA
ATTCTTCTGAGGAAAGCGTTGTTTTAAGTTAAAAACAGATAATATTTTCTTTACAAGCTTATTGTAACTT
AACGAATTAAATGATGGGCGAGGAATCGCGAATTCAACCTGTGGAAGTATTTTGTTTAGAATTTGCA
Protein Sequence 
>gi|74314929|ref|YP_313347.1| IpgB1 [Shigella sonnei Ss046] MQILNKILPQVEFAIPRPSFNSLSYNKLVKKILSVFNLKQRFPQKNFGCPVNINKIRDNVIDKIKDSNSGNQLFCWMSQERTSYVSSMINRSIDEMAIHNGVVLTSDNKKNIFAAIEKKFPDIKLDEKSAQTSISHTALNEIASSGLRAKILKRYSSNMDLFNTQMKDLTNLVSSSVYDKIFNESTKVLQIEISAEVLKAVYRQSNTN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: The invasiveness of the ipgB1 mutant was decreased to less than 50% of the wild-type level (100%) in a gentamicin protection or plaque forming assay (Ohya et al., 2005).
References
Ohya et al., 2005: Ohya K, Handa Y, Ogawa M, Suzuki M, Sasakawa C. IpgB1 is a novel Shigella effector protein involved in bacterial invasion of host cells. Its activity to promote membrane ruffling via Rac1 and Cdc42 activation. The Journal of biological chemistry. 2005; 280(25); 24022-24034. [PubMed: 15849186].