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Rv3868

Victor ID 161
Gene Name Rv3868
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 886199
NCBI Protein GI 15611004
Locus Tag Rv3868
Protein Accession NP_218385.1
Other Database IDs UniProtKB-ID: ECCA1_MYCTU
UniRef100: UniRef100_O69733
UniRef90: UniRef90_O69733
UniRef50: UniRef50_O69733
UniParc: UPI00001395C5
EMBL: BX842584
EMBL: AE000516
EMBL-CDS: CAA17960.1
EMBL-CDS: AAK48349.1
RefSeq_NT: NC_000962.2
RefSeq_NT: NC_002755.2
TCDB: 9.A.25.1.1
EnsemblGenome: EBMYCG00000003704
EnsemblGenome_TRS: EBMYCT00000003706
EnsemblGenome_PRO: EBMYCP00000003706
EnsemblGenome: EBMYCG00000072756
EnsemblGenome_TRS: EBMYCT00000072761
EnsemblGenome_PRO: EBMYCP00000070820
GenomeReviews: AE00051
Taxonomy ID 83332
Gene Starting Position 4343313
Gene Ending Position 4345034
Gene Strand (Orientation) +
Protein Name hypothetical protein
DNA Sequence 
>gi|57116681:4343313-4345034 Mycobacterium tuberculosis H37Rv, complete genome
GATGACTGATCGCTTGGCCAGTCTGTTCGAAAGCGCCGTCAGCATGTTGCCGATGTCGGAGGCGCGGTCG
CTAGATCTGTTCACCGAGATCACCAACTACGACGAATCCGCTTGCGACGCATGGATCGGCCGGATCCGGT
GTGGGGACACCGACCGGGTGACGCTGTTTCGCGCCTGGTATTCGCGCCGCAATTTCGGACAGTTGTCGGG
ATCGGTCCAGATCTCGATGAGCACGTTAAACGCCAGGATTGCCATCGGGGGGCTGTACGGCGATATCACC
TACCCGGTCACCTCGCCGCTAGCGATCACCATGGGCTTTGCCGCATGCGAGGCAGCGCAAGGCAATTACG
CCGACGCCATGGAGGCCTTAGAGGCCGCCCCGGTCGCGGGTTCCGAGCACCTGGTGGCGTGGATGAAGGC
GGTTGTCTACGGCGCGGCCGAACGCTGGACCGACGTGATCGACCAGGTCAAGAGTGCTGGGAAATGGCCG
GACAAGTTTTTGGCCGGCGCGGCCGGTGTGGCGCACGGGGTTGCCGCGGCAAACCTGGCCTTGTTCACCG
AAGCCGAACGCCGACTCACCGAGGCCAACGACTCGCCCGCCGGTGAGGCGTGTGCGCGCGCCATCGCCTG
GTATCTGGCGATGGCACGGCGCAGCCAGGGCAACGAAAGCGCCGCGGTGGCGCTGCTGGAATGGTTACAG
ACCACTCACCCCGAGCCCAAAGTGGCTGCGGCGCTGAAGGATCCCTCCTACCGGCTGAAGACGACCACCG
CCGAACAGATCGCATCCCGCGCCGATCCCTGGGATCCGGGCAGTGTCGTGACCGACAACTCCGGCCGGGA
GCGGCTGCTCGCCGAGGCCCAAGCCGAACTCGACCGCCAAATTGGGCTCACCCGGGTTAAAAATCAGATT
GAACGCTACCGCGCGGCGACGCTGATGGCCCGGGTCCGCGCCGCCAAGGGTATGAAGGTCGCCCAGCCCA
GCAAGCACATGATCTTCACCGGACCGCCCGGTACCGGCAAGACCACGATCGCGCGGGTGGTGGCCAATAT
CCTGGCCGGCTTAGGCGTCATTGCCGAACCCAAACTCGTCGAGACGTCGCGCAAGGACTTCGTCGCCGAG
TACGAGGGGCAATCGGCGGTCAAGACCGCTAAGACGATCGATCAGGCGCTGGGCGGGGTGCTTTTCATCG
ACGAGGCTTATGCGCTGGTGCAGGAAAGAGACGGCCGCACCGATCCGTTCGGTCAAGAGGCGCTGGACAC
GCTGCTGGCGCGGATGGAGAACGACCGGGACCGGCTGGTGGTGATCATCGCCGGGTACAGCTCCGACATA
GATCGGCTGCTGGAAACCAACGAGGGTCTGCGGTCGCGGTTCGCCACTCGCATCGAGTTCGACACCTATT
CCCCCGAGGAACTCCTCGAGATCGCCAACGTCATTGCCGCTGCTGATGATTCGGCGTTGACCGCAGAGGC
GGCCGAGAACTTTCTTCAGGCCGCCAAGCAGTTGGAGCAGCGCATGTTGCGCGGCCGGCGCGCCCTGGAC
GTCGCCGGCAACGGTCGGTATGCGCGCCAGCTGGTGGAGGCCAGCGAGCAATGCCGGGACATGCGTCTAG
CCCAGGTCCTCGATATCGACACCCTCGACGAAGACCGGCTTCGCGAGATCAACGGCTCAGATATGGCGGA
GGCTATCGCCGCGGTGCACGCACACCTCAACATGAGAGAATG
Protein Sequence 
>gi|15611004|ref|NP_218385.1| ESX-1 secretion system protein EccA1 [Mycobacterium tuberculosis H37Rv] MTDRLASLFESAVSMLPMSEARSLDLFTEITNYDESACDAWIGRIRCGDTDRVTLFRAWYSRRNFGQLSGSVQISMSTLNARIAIGGLYGDITYPVTSPLAITMGFAACEAAQGNYADAMEALEAAPVAGSEHLVAWMKAVVYGAAERWTDVIDQVKSAGKWPDKFLAGAAGVAHGVAAANLALFTEAERRLTEANDSPAGEACARAIAWYLAMARRSQGNESAAVALLEWLQTTHPEPKVAAALKDPSYRLKTTTAEQIASRADPWDPGSVVTDNSGRERLLAEAQAELDRQIGLTRVKNQIERYRAATLMARVRAAKGMKVAQPSKHMIFTGPPGTGKTTIARVVANILAGLGVIAEPKLVETSRKDFVAEYEGQSAVKTAKTIDQALGGVLFIDEAYALVQERDGRTDPFGQEALDTLLARMENDRDRLVVIIAGYSSDIDRLLETNEGLRSRFATRIEFDTYSPEELLEIANVIAAADDSALTAEAAENFLQAAKQLEQRMLRGRRALDVAGNGRYARQLVEASEQCRDMRLAQVLDIDTLDEDRLREINGSDMAEAIAAVHAHLNMRE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: attenuated in mice (Sassetti and Rubin, 2003).
COG COG0464O, under O: Posttranslational modification, protein turnover, chaperones
References
Sassetti and Rubin, 2003: Sassetti CM, Rubin EJ. Genetic requirements for mycobacterial survival during infection. Proceedings of the National Academy of Sciences of the United States of America. 2003; 100(22); 12989-12994. [PubMed: 14569030].