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virB from Shigella sonnei Ss046

Victor ID 1604
Gene Name virB from Shigella sonnei Ss046
Sequence Strain (Species/Organism) Shigella sonnei Ss046
NCBI Gene ID 3670829
NCBI Protein GI 74314922
Locus Tag SSON_P085
Protein Accession YP_313340.1
Other Database IDs UniProtKB-ID: Q3YTQ7_SHISS
UniRef100: UniRef100_P0A247
UniRef90: UniRef90_P0A247
UniRef50: UniRef50_P0A247
UniParc: UPI0000000B47
EMBL: CP000039
EMBL-CDS: AAZ91105.1
RefSeq_NT: NC_007385.1
EnsemblGenome: EBESCG00000101956.
EnsemblGenome_TRS: EBESCT00000102912
EnsemblGenome_PRO: EBESCP00000098772
GenomeReviews: CP000039_GR
KEGG: ssn:SSON_P085
eggNOG: COG1475
HOGENOM: HBG679439
OMA: EVNGRIE
ProtClustDB: CLSK862821
BioCyc: SSON300269:SSO_P085-MONOMER
Taxonomy ID 300269
Plasmid No pSS_046
Gene Starting Position 79011
Gene Ending Position 79940
Gene Strand (Orientation) -
Protein Name transcriptional activator required for tanscription of the ipa, mxi, and spa operons
DNA Sequence 
>gi|74314838:79011-79940 Shigella sonnei Ss046 plasmid pSS_046, complete sequence
TTTATGAAGACGATAGATGGCGAGAAATTATATCCCGAATAGCTTCATCTATTTCTCTCTGAACTGTTTT
GTTTATTTTAGATAATGTAAATATTAGAGTTCTGTTTGTTTTATTCTCTTTTCTTTTTATGTAAGTCCGT
TTGTCTTTAGAAATAAATAACGAGTCAACTTTTAGCGAAGGGTTTTGCTTTCTGTTTTTGCTTTTCTTTA
TGATGTTTAAAATTTCTTTTTTATATATGTCCGGGGGCAAATTTGTATCAAGGTCTTTTATTTCTTCCTT
TAATATTGGTAGTGTAGAACTAAGAGATTCATTAGCCTTTTCAAGTCCTTTATAATAATTGAATAATATC
TTGTAGTCATTAAAGTTAAGTTCTGACGCGATTGGAAATAGAGATATTATTTCCTGTGGAACGCTTGCTG
CCTGAAAGGCACGAGTGACTTTCGCGCGAGACAGATTCTCTTTTTTGGCTATGTCTTTATAGGACATCCC
TGATACTTTCAGAAAATTAAGACCGATACCAAGTTCTCGGATGCTATGCTCTTTTGCTGTTTGTATATCG
TTTGCTAGTTTTCTGGCATCAAGAGTAGATATATATTCTTTTGAATATAGAACTTCAAGATCTGCTCCTG
CATATATTGCAGATGCTCTTCTACGAGTGCCATCCAGAATTTCAATTCTACCATCAATCTCCCTTCCTAT
TACAGGGAAGAATTGTTGTAGCTTTATAGTTTTTATGATATCGGCTAATGATTCTTCTGTTAGGGATTCT
TGATCGCGTACATTCGTTTTTTGGTTGACGAAGGTTAAATCTTGGATCCTTTTATGAGGAATCTTGGCTT
TGATAAAGGAAACTTTATTACCAGAATGGAGTGTAAACTCTTTCTTTTGGCCTTCCTTTATACTTAACAA
GTCGTTGCACAAATCCACCA
Protein Sequence 
>gi|74314922|ref|YP_313340.1| VirB [Shigella sonnei Ss046] MVDLCNDLLSIKEGQKKEFTLHSGNKVSFIKAKIPHKRIQDLTFVNQKTNVRDQESLTEESLADIIKTIKLQQFFPVIGREIDGRIEILDGTRRRASAIYAGADLEVLYSKEYISTLDARKLANDIQTAKEHSIRELGIGLNFLKVSGMSYKDIAKKENLSRAKVTRAFQAASVPQEIISLFPIASELNFNDYKILFNYYKGLEKANESLSSTLPILKEEIKDLDTNLPPDIYKKEILNIIKKSKNRKQNPSLKVDSLFISKDKRTYIKRKENKTNRTLIFTLSKINKTVQREIDEAIRDIISRHLSSS
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: virB mutants have an avirulent phenotype and do not invade host cells (Sasakawa et al., 1993).
COG COG1475K, under K: Transcription
References
Sasakawa et al., 1993: Sasakawa C, Komatsu K, Tobe T, Suzuki T, Yoshikawa M. Eight genes in region 5 that form an operon are essential for invasion of epithelial cells by Shigella flexneri 2a. Journal of bacteriology. 1993; 175(8); 2334-2346. [PubMed: 8385666].