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aroD from Shigella sonnei Ss046

Victor ID 1601
Gene Name aroD from Shigella sonnei Ss046
Sequence Strain (Species/Organism) Shigella sonnei Ss046
NCBI Gene ID 3670791
NCBI Protein GI 74311981
Locus Tag SSON_1461
Protein Accession YP_310400.1
Other Database IDs UniProtKB-ID: AROD_SHISS
UniRef100: UniRef100_Q3Z247
UniRef90: UniRef90_A7ZMF8
UniRef50: UniRef50_Q186A6
UniParc: UPI00005AA69D
EMBL: CP000038
EMBL-CDS: AAZ88165.1
RefSeq_NT: NC_007384.1
HSSP: Q9SQT8
EnsemblGenome: EBESCG00000098708
EnsemblGenome_TRS: EBESCT00000099664
EnsemblGenome_PRO: EBESCP00000095693
GenomeReviews: CP000038_GR
KEGG: ssn:SSON_1461
eggNOG: COG0710
HOGENOM: HBG732926
OMA: NHDFDKT
ProtClustDB: PRK02412
BioCyc: SSON300269:SSO_1461-MONOMER
Taxonomy ID 300269
Gene Starting Position 1534973
Gene Ending Position 1535731
Gene Strand (Orientation) -
Protein Name 3-dehydroquinate dehydratase
DNA Sequence 
>gi|74310614:1534973-1535731 Shigella sonnei Ss046, complete genome
CTTATGCCTGGTGTAAAATAGTTAATACCGTGCGTAAATCATTTACCGAGATTTGCCCTGGTGCAGAGGC
TTTTTTTACCGCACCAAAAGTTGCCGCCGAGCCAAATACTTCACCAGCCAGACGAGAAATTACGCCAGTT
TTTGCCATCGACATCGTGATGATTGGACGATCGGCATACTGCTCCTGCATCTCCAGGGTCGCGGTAAGCA
ACGTCAGCACATCGCTGGTACTTTGCGGCATCAGCGCAATCTTAGGAATATCGGCGTCGAAGGACTGCAT
TTTGCGCAGACGGGCAATGATTTCTTCGGCTTCCGGCGTTTTATGGAAGTCATGGTTGGACATGACAACT
TTCACATCATGCGCGTGGGCGTAGGCGACGGTTTCTTTAACCTGATCATCGCCGGTAAATAACTCCAGAT
CGATCATATCAACCAGGCCGCTGTCGATGGCTGCACGATTGAGAGCAATATAAGCCTCGGTGGAAATCGC
CTGCTCGCCGCCTTCTTTGGCACTGCGGAAGGTAAACAGCAGCGGTTTTTCTGGCATGGTTTCACGGAGA
ATTTTTGCCGCCGCCATGACAGACTCCACATTGGAGAGGTCGGCAAAGTGGTCCACACGCCATTCCAGAA
TATCAAAGTCCGCTTCACGATAGGCGAGAGCTTCGGATTTCACGCGGGCGATATCTTTCGCCATCAGCGA
GACGATGATTTTAGGTGCGCCCGCACCAATGACGAGATCTTTTACAGTTACGGTTTTCA
Protein Sequence 
>gi|74311981|ref|YP_310400.1| 3-dehydroquinate dehydratase [Shigella sonnei Ss046] MKTVTVKDLVIGAGAPKIIVSLMAKDIARVKSEALAYREADFDILEWRVDHFADLSNVESVMAAAKILRETMPEKPLLFTFRSAKEGGEQAISTEAYIALNRAAIDSGLVDMIDLELFTGDDQVKETVAYAHAHDVKVVMSNHDFHKTPEAEEIIARLRKMQSFDADIPKIALMPQSTSDVLTLLTATLEMQEQYADRPIITMSMAKTGVISRLAGEVFGSAATFGAVKKASAPGQISVNDLRTVLTILHQA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: aroD deletion led to attenuation in HeLa cells and monkeys (Kärnell et al., 1993).
COG COG0710E, under E: Amino acid transport and metabolism
References
Kärnell et al., 1993: Kärnell A, Cam PD, Verma N, Lindberg AA. AroD deletion attenuates Shigella flexneri strain 2457T and makes it a safe and efficacious oral vaccine in monkeys. Vaccine. 1993; 11(8); 830-836. [PubMed: 8356844].