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esxB from Mycobacterium tuberculosis H37Rv

Victor ID 160
Gene Name esxB from Mycobacterium tuberculosis H37Rv
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 886194
NCBI Protein GI 15611010
Locus Tag Rv3874
Protein Accession NP_218391.1
Other Database IDs UniProtKB-ID: ESXB_MYCTU
UniRef100: UniRef100_P0A567
UniRef90: UniRef90_P0A567
UniRef50: UniRef50_P0A567
UniParc: UPI0000036DD2
EMBL: AF004671
EMBL: AF419854
EMBL: BX842584
EMBL: AE000516
EMBL-CDS: AAC83445.1
EMBL-CDS: AAL14999.1
EMBL-CDS: CAA17966.1
EMBL-CDS: AAK48356.1
RefSeq_NT: NC_000962.2
RefSeq_NT: NC_002755.2
PDB: 3FAV
TCDB: 9.A.25.1.1
EnsemblGenome: EBMYCG00000000384
EnsemblGenome_TRS: EBMYCT00000000384
EnsemblGenome_PRO: EBMYCP00000000384
EnsemblGenome: EBMYCG00000072582
EnsemblGenome_T
Taxonomy ID 83332
Gene Starting Position 4352273
Gene Ending Position 4352575
Gene Strand (Orientation) +
Protein Name 10 KDA CULTURE FILTRATE ANTIGEN ESXB (LHP) (CFP10)
DNA Sequence 
>gi|57116681:4352273-4352575 Mycobacterium tuberculosis H37Rv, complete genome
CATGGCAGAGATGAAGACCGATGCCGCTACCCTCGCGCAGGAGGCAGGTAATTTCGAGCGGATCTCCGGC
GACCTGAAAACCCAGATCGACCAGGTGGAGTCGACGGCAGGTTCGTTGCAGGGCCAGTGGCGCGGCGCGG
CGGGGACGGCCGCCCAGGCCGCGGTGGTGCGCTTCCAAGAAGCAGCCAATAAGCAGAAGCAGGAACTCGA
CGAGATCTCGACGAATATTCGTCAGGCCGGCGTCCAATACTCGAGGGCCGACGAGGAGCAGCAGCAGGCG
CTGTCCTCGCAAATGGGCTTCTG
Protein Sequence 
>gi|15611010|ref|NP_218391.1| ESAT-6-like protein EsxB [Mycobacterium tuberculosis H37Rv] MAEMKTDAATLAQEAGNFERISGDLKTQIDQVESTAGSLQGQWRGAAGTAAQAAVVRFQEAANKQKQELDEISTNIRQAGVQYSRADEEQQQALSSQMGF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: esxB (CFP-10) mutant is attenuated in mice (Fortune et al., 2005).
References
Fortune et al., 2005: Fortune SM, Jaeger A, Sarracino DA, Chase MR, Sassetti CM, Sherman DR, Bloom BR, Rubin EJ. Mutually dependent secretion of proteins required for mycobacterial virulence. Proceedings of the National Academy of Sciences of the United States of America. 2005; 102(30); 10676-10681. [PubMed: 16030141].