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iucD from Shigella sonnei Ss046

Victor ID 1598
Gene Name iucD from Shigella sonnei Ss046
Sequence Strain (Species/Organism) Shigella sonnei Ss046
NCBI Gene ID 3670428
NCBI Protein GI 74313971
Locus Tag SSON_3604
Protein Accession YP_312390.1
Other Database IDs UniProtKB-ID: Q3YWF7_SHISS
UniRef100: UniRef100_B2TXY2
UniRef90: UniRef90_P11295
UniRef50: UniRef50_P11295
UniParc: UPI00005AAB13
EMBL: CP000038
EMBL-CDS: AAZ90155.1
RefSeq_NT: NC_007384.1
EnsemblGenome: EBESCG00000098389.
EnsemblGenome_TRS: EBESCT00000099345
EnsemblGenome_PRO: EBESCP00000095374
GenomeReviews: CP000038_GR
KEGG: ssn:SSON_3604
eggNOG: COG3486
HOGENOM: HBG415390
OMA: SAVYPES
ProtClustDB: CLSK888708
BioCyc: SSON300269:SSO_3604-MONOMER
Taxonomy ID 300269
Gene Starting Position 3771960
Gene Ending Position 3773297
Gene Strand (Orientation) +
Protein Name lysine:N6-hydroxylase
DNA Sequence 
>gi|74310614:3771960-3773297 Shigella sonnei Ss046, complete genome
CATGAAAAAAAGTGTCGATTTTATTGGTGTCGGGACAGGGCCATTTAATCTCAGCATTGCTGCATTGTCA
CATCAGATCGAAGAACTGAACTGTCTCTTCTTTGACGAACATCCTCATTTTTCCTGGCATCCGGGTATGC
TGGTACCGGATTGTCATATGCAGACCGTCTTTCTGAAAGATCTGGTCAGTGCAGTTGCACCTACAAATCC
CTACAGCTTTGTTAACTATCTGGTGAAGCACAAAAAGTTCTATCGCTTCCTTACAAGCAGGCTACGTACA
GTATCCCGTGAAGAGTTTTCTGACTATCTCCGCTGGGCTGCTGAAGATATGAATAACCTGTATTTCAGTC
ATACCGTTGAAAATATTGATTTCGACAAAAAAAGTCGATTGTTTCTGGTTCAGACCAGTCGGGGAGAATA
TTTTGCCCGCAATATCTGCCTTGGTACAGGAAAACAACCTTATTTACCACCCTGTGTGAAGCATGTGACA
CAATCCTGTTTCCATGCCAGTGAAATGAATCTTCGTCGGCCGGACCTGAGTGGAAAACGGATAACCGTGG
TTGGTGGAGGACAGAGTGGTGCAGACCTGTTCCTTAATGCATTACGCGGGGAATGGGGAGAAGCGGCGGA
AATAAACTGGGTCTCACGGCGTAATAATTTTAACGCACTGGATGAGGCTGCTTTTGCTGATGAGTATTTT
ACACCTGAATATATTTCAGGCTTCTCCGGACTGAAGGAAGATATTCGCCATCAGTTACTGGATGAGCAGA
AAATGACATCGGATGGCATCACTGCCGATTCTTTACTGACCATTTATCGTGAGTTGTACCACCGTTTTGA
AGTTCTGAGAAAACCAAGAAATATCCGTCTGCTACCCAGTCGCTCGGTAACAACCCTGGAAAGTAGTGGT
CCGGGCTGGAGGTTATTGATGGAACATCATCTGGATCAGGGCAGAGAGAGCCTGGAAAGTGATGTGGTGA
TTTTCGCCACAGGTTACCGTTCTGCATTGCCACAAATACTTCCCTCACTGATGCCCTTGATCACCATGCA
CGATAAGAACACCTTTAAAGTGCGTGATGACTTCACTCTGGAATGGAGTGGCCCGAAAGAAAATAACATC
TTTGCGGTCAACGCCAGCATGCAAACTCATGGCATCGCCGAACCCCAGCTCAGCCTGATGGCCTGGCGAT
CTGCACGTATTCTTAATCGCGTACTGGGGCGTGATTTATTCGATCTCAGTATGCCGCCCGCACTGATTCA
GTGGCGCAGCGGCAGCCGGAAAAAACCGCAGCCGGAGGCTGCTTCTTTAACTCACTATACAGCAAATATT
CAGGAATA
Protein Sequence 
>gi|74313971|ref|YP_312390.1| lysine:N6-hydroxylase [Shigella sonnei Ss046] MKKSVDFIGVGTGPFNLSIAALSHQIEELNCLFFDEHPHFSWHPGMLVPDCHMQTVFLKDLVSAVAPTNPYSFVNYLVKHKKFYRFLTSRLRTVSREEFSDYLRWAAEDMNNLYFSHTVENIDFDKKSRLFLVQTSRGEYFARNICLGTGKQPYLPPCVKHVTQSCFHASEMNLRRPDLSGKRITVVGGGQSGADLFLNALRGEWGEAAEINWVSRRNNFNALDEAAFADEYFTPEYISGFSGLKEDIRHQLLDEQKMTSDGITADSLLTIYRELYHRFEVLRKPRNIRLLPSRSVTTLESSGPGWRLLMEHHLDQGRESLESDVVIFATGYRSALPQILPSLMPLITMHDKNTFKVRDDFTLEWSGPKENNIFAVNASMQTHGIAEPQLSLMAWRSARILNRVLGRDLFDLSMPPALIQWRSGSRKKPQPEAASLTHYTANIQE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: iuc mutants are attenuated in chicken embryos and rabbit ileal loops (Wyckoff et al., 2009).
COG COG3486Q, under Q: Secondary metabolites biosynthesis, transport and catabolism
References
Wyckoff et al., 2009: Wyckoff EE, Boulette ML, Payne SM. Genetics and environmental regulation of Shigella iron transport systems. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine. 2009; 22(1); 43-51. [PubMed: 19130265].