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aroA from Shigella sonnei Ss046

Victor ID 1595
Gene Name aroA from Shigella sonnei Ss046
Sequence Strain (Species/Organism) Shigella sonnei Ss046
NCBI Gene ID 3670343
NCBI Protein GI 74311464
Locus Tag SSON_0909
Protein Accession YP_309883.1
Other Database IDs UniProtKB-ID: AROA_SHISS
UniRef100: UniRef100_A7ZJZ7
UniRef90: UniRef90_A8AIH5
UniRef50: UniRef50_B1JXR9
UniParc: UPI0000113012
EMBL: CP000038
EMBL-CDS: AAZ87648.1
RefSeq_NT: NC_007384.1
HSSP: P0A6D3
EnsemblGenome: EBESCG00000100185
EnsemblGenome_TRS: EBESCT00000101141
EnsemblGenome_PRO: EBESCP00000097170
GenomeReviews: CP000038_GR
KEGG: ssn:SSON_0909
eggNOG: COG0128
HOGENOM: HBG646626
OMA: GADIEWG
ProtClustDB: PRK02427
BioCyc: SSON300269:SSO_0909-MONOMER
Taxonomy ID 300269
Gene Starting Position 973080
Gene Ending Position 974363
Gene Strand (Orientation) +
Protein Name 3-phosphoshikimate 1-carboxyvinyltransferase
DNA Sequence 
>gi|74310614:973080-974363 Shigella sonnei Ss046, complete genome
CATGGAATCCCTGACGTTACAACCCATCGCTCGTGTCGATGGCACTATTAATCTGCCCGGTTCCAAGAGC
GTTTCTAACCGCGCTTTATTGCTGGCGGCATTAGCACACGGCAAAACAGTATTAACCAATCTGCTGGATA
GCGATGACGTGCGCCATATGCTGAATGCATTAACAGCGTTAGGGGTAAGCTATACGCTTTCAGCCGATCG
TACGCGTTGCGAAATTATCGGTAACGGCGGTCCATTACACGCAGAAGGTGCCCTGGAGTTGTTCCTCGGT
AACGCCGGAACGGCAATGCGTCCGCTGGCGGCAGCTCTTTGTCTGGGTAGCAATGATATTGTGCTGACCG
GTGAGCCGCGTATGAAAGAACGCCCGATTGGTCATCTGGTGGATGCGCTGCGCCTGGGCGGGGCGAAGAT
CACTTACCTGGAACAAGAAAATTATCCGCCGTTGCGTTTACAGGGCGGCTTTACTGGCGGCAACGTTGAC
GTTGATGGCTCCGTTTCCAGCCAATTCCTCACCGCACTGTTAATGACTGCGCCTCTTGCGCCGGAAGATA
CGGTGATTCGTATTAAAGGCGATCTGGTTTCTAAACCTTATATCGACATCACACTCAATCTGATGAAGAC
GTTTGGTGTTGAAATTGAAAATCAGCACTATCAACAATTTGTCGTAAAAGGCGGGCAGTCTTATCAGTCT
CCGGGTACTTATTTGGTCGAAGGCGATGCATCTTCGGCTTCTTACTTTCTGGCAGCAGCAGCAATCAAAG
GCGGCACTGTAAAAGTGACCGGTATTGGACGTAACAGTATGCAGGGTGATATTCGCTTTGCTGATGTGCT
GGAAAAAATGGGCGCGACCATTTGCTGGGGCGATGATTATATTTCCTGCACGCGTGGTGAACTGAACGCT
ATTGATATGGATATGAACCATATTCCCGATGCGGCGATGACCATTGCCACGGCGGCGTTATTTGCAAAAG
GCACCACCACGCTGCGCAATATCTATAACTGGCGTGTTAAAGAGACCGATCGCCTGTTTGCGATGGCAAC
AGAACTGCGTAAAGTCGGTGCGGAAGTAGAAGAGGGGCACGATTACATTCGTATCACTCCACCGGAAAAA
CTGAACTTTGCCGAGATCGCGACATACAATGATCACCGGATGGCGATGTGTTTCTCGCTGGTGGCGTTGT
CAGATACACCAGTGACGATTCTTGATCCCAAATGTACGGCCAAAACATTTCCGGATTATTTCGAGCAGTT
GGCGCGGATTAGCCAGGCAGCCTG
Protein Sequence 
>gi|74311464|ref|YP_309883.1| 3-phosphoshikimate 1-carboxyvinyltransferase [Shigella sonnei Ss046] MESLTLQPIARVDGTINLPGSKSVSNRALLLAALAHGKTVLTNLLDSDDVRHMLNALTALGVSYTLSADRTRCEIIGNGGPLHAEGALELFLGNAGTAMRPLAAALCLGSNDIVLTGEPRMKERPIGHLVDALRLGGAKITYLEQENYPPLRLQGGFTGGNVDVDGSVSSQFLTALLMTAPLAPEDTVIRIKGDLVSKPYIDITLNLMKTFGVEIENQHYQQFVVKGGQSYQSPGTYLVEGDASSASYFLAAAAIKGGTVKVTGIGRNSMQGDIRFADVLEKMGATICWGDDYISCTRGELNAIDMDMNHIPDAAMTIATAALFAKGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVEEGHDYIRITPPEKLNFAEIATYNDHRMAMCFSLVALSDTPVTILDPKCTAKTFPDYFEQLARISQAA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: aroA deletion mutants are attenuated in HeLa cells (Noriega et al., 1996).
COG COG0128E, under E: Amino acid transport and metabolism
References
Noriega et al., 1996: Noriega FR, Losonsky G, Lauderbaugh C, Liao FM, Wang JY, Levine MM. Engineered deltaguaB-A deltavirG Shigella flexneri 2a strain CVD 1205: construction, safety, immunogenicity, and potential efficacy as a mucosal vaccine. Infection and immunity. 1996; 64(8); 3055-3061. [PubMed: 8757833].