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vacB from Shigella sonnei Ss046

Victor ID 1590
Gene Name vacB from Shigella sonnei Ss046
Sequence Strain (Species/Organism) Shigella sonnei Ss046
NCBI Gene ID 3668484
NCBI Protein GI 161986382
Locus Tag SSON_4364
Protein Accession YP_313083.2
Other Database IDs UniProtKB-ID: Q3YUG4_SHISS
UniRef100: UniRef100_Q3YUG4
UniRef90: UniRef90_P21499
UniRef50: UniRef50_P21499
UniParc: UPI00005AAC6C
EMBL: CP000038
EMBL-CDS: AAZ90848.1
RefSeq_NT: NC_007384.1
EnsemblGenome: EBESCG00000100590.
EnsemblGenome_TRS: EBESCT00000101546
EnsemblGenome_PRO: EBESCP00000097575
GenomeReviews: CP000038_GR
KEGG: ssn:SSON_4364
eggNOG: COG0557
HOGENOM: HBG690243
OMA: TTERMTY
ProtClustDB: PRK11642
BioCyc: SSON300269:SSO_4364-MONOMER
Taxonomy ID 300269
Gene Starting Position 4633502
Gene Ending Position 4635943
Gene Strand (Orientation) +
Protein Name exoribonuclease R
DNA Sequence 
>gi|74310614:4633502-4635943 Shigella sonnei Ss046, complete genome
GATGTCACAAGATCCTTTCCAGGAACGCGAAGCTGAAAAATACGCGAATCCCATCCCTAGTCGGGAATTT
ATCCTCGAACATTTAACCAAACGTGAAAAACCGGCCAGCCGTGATGAGCTGGCGGTAGAACTGCACATTG
AAGGCGAAGAGCAGCTTGAAGGCCTGCGTCGCCGCCTGCGCGCGATGGAGCGCGATGGTCAACTGGTCTT
CACTCGTCGTCAGTGCTATGCGCTGCCGGAACGCCTCGACCTGGTGAAAGGTACCGTTATTGGCCACCGT
GATGGCTACGGCTTTCTGCGGGTTGAAGGGCGTAAAGATGATTTGTATCTCTCCAGCGAGCAGATGAAAA
CCTGTATTCATGGCGATCAGGTGCTGGCGCAGCCGCTGGGTGCTGACCGTAAAGGTCGTCGTGAAGCGCG
TATTGTCCGCGTACTGGTGCCAAAAACCAGCCAGATTGTTGGTCGCTACTTTACCGAAGCGGGCGTCGGC
TTTGTGGTTCCTGACGATAGCCGTCTGAGCTTCGATATCTTAATCCCGCCCGATCAGATCATGGGCGCGC
GGATGGGCTTTGTGGTCGTAGTCGAACTGACTCAGCGTCCGACTCGCCGCACCAAAGCGGTGGGTAAAAT
CGTCGAAGTGCTGGGCGACAATATGGGCACCGGCATGGCGGTTGATATCGCTCTGCGTACCCATGAAATT
CCGTATATCTGGCCGCAGGCTGTTGAGCAACAGGTTGCGGGGCTGAAAGAAGAAGTGCCGGAAGAAGCAA
AAGCGGGCCGTGTCGATTTGCGCGATTTACCGCTGGTCACCATTGATGGCGAAGACGCCCGTGACTTTGA
CGATGCAGTTTACTGCGAGAAAAAACGCGGCGGCGGCTGGCGTTTATGGGTCGCGATTGCCGACGTCAGC
TACTATGTGCGTCCGCCAACGCCGCTGGACAGAGAAGCGCGTAACCGTGGCACGTCGGTGTACTTCCCTT
CGCAGGTTATCCCGATGCTGCCGGAAGTGCTCTCTAACGGCCTGTGTTCGCTCAACCCGCAGGTAGACCG
CCTGTGTATGGTGTGCGAGATGACGGTTTCGTCGAAAGGCCGCCTGACGGGCTACAAATTCTACGAAGCG
GTGATGAGCTCTCACGCGCGTCTGACCTACACCAAAGTCTGGCATATTCTGCAGGGCGATCAGGATCTGC
GCGAGCAGTACGTCCCGCTGGTTAAGCATCTCGAAGAGTTGCATAACCTCTATAAAGTGCTGGATAAAGC
CCGTGAAGAACGCGGTGGGATCTCATTTGAGAGCGAAGAAGCGAAGTTCATTTTCAACGCTGAACGCCGT
ATTGAACGTATCGAACAGACCCAGCGTAACGACGCGCACAAATTAATTGAAGAGTGCATGATTCTGGCGA
ATATCTCGGCGGCGCGTTTCGTTGAGAAAGCGAAAGAACCGGCACTGTTCCGTATTCACGACAAGCCGAG
CACCGAAGCGATTACCTCTTTCCGTTCAGTGCTGGCGGAGCTGGGGCTGGAGCTGCCGGGTGGTAACAAG
CCGGAACCGCGTGACTACGCGGAACTGCTGGAGTCGGTTGCCGACCGTCCTGATGCAGAAATGCTGCAAA
CCATGCTGCTGCGCTCGATGAAACAGGCGATTTACGATCCAGAAAACCGTGGTCACTTTGGCCTGGCATT
GCAGTCCTATGCGCACTTTACTTCGCCGATTCGTCGTTATCCTGACCTGACGCTGCACCGCGCCATTAAG
TATCTGCTGGCGAAAGAGCAGGGGCATCAGGGCAACACCACTGAAACCGGCGGCTACCATTATTCGATGG
AAGAGATGTTGCAACTGGGTCAGCACTGTTCGATGGCGGAACGTCGTGCCGACGAAGCAACGCGCGATGT
CGCTGACTGGCTGAAGTGTGACTTCATGCTCGACCAGGTAGGTAACGTCTTTAAAGGCGTAATTTCCAGC
GTCACTGGCTTTGGCTTCTTCGTCCGTCTGGACGACTTGTTCATTGATGGTCTGGTCCATGTCTCTTCGC
TGGACAATGACTACTATCGCTTTGACCAGGTAGGGCAACGCCTGATGGGGGAATCCAGCGGCCAGACTTA
TCGCCTGGGCGATCGCGTGGAAGTTCGCGTCGAAGCGGTTAATATGGACGAGCGCAAAATCGACTTTAGT
CTGATCTCCAGTGAACGCGCACCGCGCAACGTCGGTAAAACGGCGCGCGAGAAAGCGAAAAAAGGCGATG
CAGGCAAAAAAGGCGGCAAGCGTCGTCAGGTCGGTAAAAAGGTAAACTTTGAGCCAGACAGCGCCTTCCG
CGGTGAGAAAAAAACGAAGCCGAAAGCGGCGAAGAAAGACGCGAGAAAAGCGAAAAAGCCATCGGCGAAA
ACGCAGAAAATAGCCGCAGCGACCAAAGCGAAGCGTGCGGCGAAGAAAAAAGTGGCAGAGTG
Protein Sequence 
>gi|161986382|ref|YP_313083.2| exoribonuclease R [Shigella sonnei Ss046] MSQDPFQEREAEKYANPIPSREFILEHLTKREKPASRDELAVELHIEGEEQLEGLRRRLRAMERDGQLVFTRRQCYALPERLDLVKGTVIGHRDGYGFLRVEGRKDDLYLSSEQMKTCIHGDQVLAQPLGADRKGRREARIVRVLVPKTSQIVGRYFTEAGVGFVVPDDSRLSFDILIPPDQIMGARMGFVVVVELTQRPTRRTKAVGKIVEVLGDNMGTGMAVDIALRTHEIPYIWPQAVEQQVAGLKEEVPEEAKAGRVDLRDLPLVTIDGEDARDFDDAVYCEKKRGGGWRLWVAIADVSYYVRPPTPLDREARNRGTSVYFPSQVIPMLPEVLSNGLCSLNPQVDRLCMVCEMTVSSKGRLTGYKFYEAVMSSHARLTYTKVWHILQGDQDLREQYVPLVKHLEELHNLYKVLDKAREERGGISFESEEAKFIFNAERRIERIEQTQRNDAHKLIEECMILANISAARFVEKAKEPALFRIHDKPSTEAITSFRSVLAELGLELPGGNKPEPRDYAELLESVADRPDAEMLQTMLLRSMKQAIYDPENRGHFGLALQSYAHFTSPIRRYPDLTLHRAIKYLLAKEQGHQGNTTETGGYHYSMEEMLQLGQHCSMAERRADEATRDVADWLKCDFMLDQVGNVFKGVISSVTGFGFFVRLDDLFIDGLVHVSSLDNDYYRFDQVGQRLMGESSGQTYRLGDRVEVRVEAVNMDERKIDFSLISSERAPRNVGKTAREKAKKGDAGKKGGKRRQVGKKVNFEPDSAFRGEKKTKPKAAKKDARKAKKPSAKTQKIAAATKAKRAAKKKVAE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: vacB mutants had attenuated invasion of MK2 cells compared to the wild-type strain (Tobe et al., 1992).
COG COG0557K, under K: Transcription
References
Tobe et al., 1992: Tobe T, Sasakawa C, Okada N, Honma Y, Yoshikawa M. vacB, a novel chromosomal gene required for expression of virulence genes on the large plasmid of Shigella flexneri. Journal of bacteriology. 1992; 174(20); 6359-6367. [PubMed: 1400189].