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miaA from Shigella sonnei Ss046

Victor ID 1588
Gene Name miaA from Shigella sonnei Ss046
Sequence Strain (Species/Organism) Shigella sonnei Ss046
NCBI Gene ID 3668476
NCBI Protein GI 74314656
Locus Tag SSON_4356
Protein Accession YP_313075.1
Other Database IDs UniProtKB-ID: MIAA_SHISS
UniRef100: UniRef100_A7ZV40
UniRef90: UniRef90_A8AMN0
UniRef50: UniRef50_Q7U347
UniParc: UPI000012F0BD
EMBL: CP000038
EMBL-CDS: AAZ90840.1
RefSeq_NT: NC_007384.1
EnsemblGenome: EBESCG00000099723
EnsemblGenome_TRS: EBESCT00000100679
EnsemblGenome_PRO: EBESCP00000096708
GenomeReviews: CP000038_GR
KEGG: ssn:SSON_4356
eggNOG: COG0324
HOGENOM: HBG559459
OMA: VNADSMQ
ProtClustDB: PRK00091
BioCyc: SSON300269:SSO_4356-MONOMER
Taxonomy ID 300269
Gene Starting Position 4626099
Gene Ending Position 4627049
Gene Strand (Orientation) +
Protein Name tRNA delta(2)-isopentenylpyrophosphate transferase
DNA Sequence 
>gi|74310614:4626099-4627049 Shigella sonnei Ss046, complete genome
GATGAGTGATATCAGTAAGGCGAGCCTGCCTAAGGCGATTTTTTTGATGGGGCCGACGGCCTCCGGTAAA
ACGGCGTTAGCCATTGAGCTGCGTAAAATTTTACCAGTAGAGTTGATAAGCGTTGATTCTGCCCTTATTT
ACAAAGGGATGGATATCGGGACGGCGAAGCCGAACGCTGAAGAGTTACTCGCCGCGCCGCACCGATTGCT
GGATATTCGCGATCCGTCGCAGGCTTACTCGGCTGCTGATTTTCGCCGCGATGCGCTGGCGGAAATGGCC
GATATCACCGCGGCGGGGCGGATCCCACTGTTAGTGGGCGGTACGATGTTGTATTTCAAGGCATTGCTGG
AAGGGTTGTCGCCGCTACCGTCGGCAGACCCGGAAGTGCGGGCCAGAATTGAGCAACAGGCGGCAGAGCA
AGGTTGGGAGTCATTGCATCGTCAACTTCAGGAGGTAGATCCGGTTGCGGCAGCAAGGATTCATCCAAAT
GATCCACAAAGGCTTTCCCGGGCACTGGAAGTTTTTTTCATTTCGGGTAAAACTTTAACGGAACTGACGC
AAACGTCAGGAGACGCTCTACCGTATCAGGTGCATCAGTTCGCCATCGCCCCGGCGAGCCGTGAACTGCT
CCATCAACGCATTGAGCAGCGTTTTCATCAGATGTTGGCTTCAGGTTTTGAAGCAGAAGTCCGGGCGCTT
TTTGCCCGAGGAGATTTGCATACGGACTTGCCTTCCATTCGTTGCGTGGGTTATCGCCAGATGTGGTCTT
ACCTTGAAGGCGAAATCTCATACGATGAAATGGTTTATCGAGGTGTTTGCGCCACGAGACAGTTGGCGAA
GCGGCAGATAACCTGGCTGCGTGGTTGGGAAGGGGTTCACTGGCTTGACAGTGAAAAACCAGAACAGGCG
CGTGACGAAGTATTACAGGTTGTTGGTGCTATCGCAGGCTG
Protein Sequence 
>gi|74314656|ref|YP_313075.1| tRNA delta(2)-isopentenylpyrophosphate transferase [Shigella sonnei Ss046] MSDISKASLPKAIFLMGPTASGKTALAIELRKILPVELISVDSALIYKGMDIGTAKPNAEELLAAPHRLLDIRDPSQAYSAADFRRDALAEMADITAAGRIPLLVGGTMLYFKALLEGLSPLPSADPEVRARIEQQAAEQGWESLHRQLQEVDPVAAARIHPNDPQRLSRALEVFFISGKTLTELTQTSGDALPYQVHQFAIAPASRELLHQRIEQRFHQMLASGFEAEVRALFARGDLHTDLPSIRCVGYRQMWSYLEGEISYDEMVYRGVCATRQLAKRQITWLRGWEGVHWLDSEKPEQARDEVLQVVGAIAG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: miaA mutants had reduced ability to invade and spread in MK2 cell monolayers compared to the wildtype (Durand et al., 1997).
COG COG0324J, under J: Translation, ribosomal structure and biogenesis
References
Durand et al., 1997: Durand JM, Björk GR, Kuwae A, Yoshikawa M, Sasakawa C. The modified nucleoside 2-methylthio-N6-isopentenyladenosine in tRNA of Shigella flexneri is required for expression of virulence genes. Journal of bacteriology. 1997; 179(18); 5777-5782. [PubMed: 9294434].