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senB

Victor ID 1587
Gene Name senB
Sequence Strain (Species/Organism) Shigella sonnei Ss046
NCBI Gene ID 3668265
NCBI Protein GI 74313104
Locus Tag SSON_2665
Protein Accession YP_311523.1
Other Database IDs UniProtKB-ID: Q3YYX4_SHISS
UniRef100: UniRef100_B3HYH8
UniRef90: UniRef90_Q31SK6
UniRef50: UniRef50_Q47628
UniParc: UPI00005AA952
EMBL: CP000038
EMBL-CDS: AAZ89288.1
RefSeq_NT: NC_007384.1
EnsemblGenome: EBESCG00000098814.
EnsemblGenome_TRS: EBESCT00000099770
EnsemblGenome_PRO: EBESCP00000095799
GenomeReviews: CP000038_GR
KEGG: ssn:SSON_2665
eggNOG: COG3391
HOGENOM: HBG417034
OMA: RFEHLRH
ProtClustDB: CLSK939804
BioCyc: SSON300269:SSO_2665-MONOMER
Taxonomy ID 300269
Gene Starting Position 2824138
Gene Ending Position 2825313
Gene Strand (Orientation) +
Protein Name putative enterotoxin
DNA Sequence 
>gi|74310614:2824138-2825313 Shigella sonnei Ss046, complete genome
AATGAATATTTTCACTTTATCCAAAGCACCGCTATACCTGTTAATTTCACTATTTTTACCCACGATGGCC
ATGGCTATCGATCCACCTGAACGCGAACTTTCGCGATTTGCCCTGAAAACGAATTACCTTCAGTCCCCTG
ATGAAGGCGTCTATGAACTGGCGTTTGATAATGCCAGTAAAAAGGTGTTTGCAGCAGTCACCGATCGTGT
AAATCGTGAAGCCAATAAAGGCTATCTGTATTCGTTTAATTCAGATTCGCTGAAAGTCGAAAATAAATAC
ACGATGCCATACCGGGCATTTTCGCTGGCGATAAATCAGGATAAACATCAGCTCTATATCGGACACACCC
AGTCAGCGTCCCTGCGTATCAGTATGTTTGACACCCCAACCGGCAAACTGGTAAGAACCAGCGACAGGTT
AAGTTTTAAAGCGGCAAACGCTGCAGATTCGCGTTTTGAGCATTTTCGCCATATGGTTTACAGCCAGGAT
TCCGATACCCTGTTTGTGAGTTATAGCAATATGCTGAAAACGGCCGAGGGCATGAAGCCTCTGCATAAGC
TGTTAATGCTCGACGGGACGACGCTTGCCTTAAAAGGCGAGGTTAAGGATGCTTACAAAGGTACAGCGTA
TGGTCTGACGATGGATGAAAAAACACAGAAAATCTACGTTGGCGGAAGAGATTACATCAACGAAATTGAT
GCGAAAAATCAGACGCTGCTGCGTACCATCCCGTTGAAAGATCCGAGACCACAAATCACAAGTGTGCAGA
ATCTGGCGGTGGACTCCGCTTCTGACCGTGCCTTTGTGGTGGTATTCGACCATGACGATCGTTCCGGTAC
AAAAGATGGACTCTATATTTTTGACTTACGCGACGGTAAACAGCTTGGCTATGTGCACACAGGAGCCGGA
GCTAACGCGGTGAAATACAATCCGAAATATAACGAACTGTATGTCACCAACTTCACTAGCGGCACCATCA
GCGTAGTGGATGCCACCAAATACAGCATCACCCGTGAATTTAACATGCCGGTCTACCCAAACCAGATGGT
GTTGTCGGACGATATGGATACCCTTTACATTGGCATCAAAGAAGGCTTTAACCGCGATTGGGATCCTGAT
GTGTTTGTGGAAGGAGCTAAAGAACGTATTCTGAGCATTGATTTGAAAAAGTCGTG
Protein Sequence 
>gi|74313104|ref|YP_311523.1| enterotoxin [Shigella sonnei Ss046] MNIFTLSKAPLYLLISLFLPTMAMAIDPPERELSRFALKTNYLQSPDEGVYELAFDNASKKVFAAVTDRVNREANKGYLYSFNSDSLKVENKYTMPYRAFSLAINQDKHQLYIGHTQSASLRISMFDTPTGKLVRTSDRLSFKAANAADSRFEHFRHMVYSQDSDTLFVSYSNMLKTAEGMKPLHKLLMLDGTTLALKGEVKDAYKGTAYGLTMDEKTQKIYVGGRDYINEIDAKNQTLLRTIPLKDPRPQITSVQNLAVDSASDRAFVVVFDHDDRSGTKDGLYIFDLRDGKQLGYVHTGAGANAVKYNPKYNELYVTNFTSGTISVVDATKYSITREFNMPVYPNQMVLSDDMDTLYIGIKEGFNRDWDPDVFVEGAKERILSIDLKKS
Molecule Role Virulence factor
Molecule Role Annotation TOXIN: ShET2 was found to induce fluid secretion into the intestine, thus accounting for the watery phase of diarrhea (Schroeder and Hilbi, 2008).
COG COG3391S, under S: Function unknown
References
Schroeder and Hilbi, 2008: Schroeder GN, Hilbi H. Molecular pathogenesis of Shigella spp.: controlling host cell signaling, invasion, and death by type III secretion. Clinical microbiology reviews. 2008; 21(1); 134-156. [PubMed: 18202440].