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ethR

Victor ID 158
Gene Name ethR
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 886189
NCBI Protein GI 15610991
Locus Tag Rv3855
Protein Accession NP_218372.1
Other Database IDs UniProtKB-ID: ETHR_MYCTU
UniRef100: UniRef100_Q7TVI1
UniRef90: UniRef90_Q7TVI1
UniRef50: UniRef50_Q7TVI1
UniParc: UPI00000D5E34
EMBL: AE000516
EMBL: BX842584
EMBL-CDS: AAK48337.1
EMBL-CDS: CAB06235.1
RefSeq_NT: NC_000962.2
RefSeq_NT: NC_002755.2
PDB: 1T56
PDB: 1U9N
PDB: 1U9O
PDB: 3G1L
PDB: 3G1M
PDB: 3G1O
PDB: 3O8G
PDB: 3O8H
EnsemblGenome: EBMYCG00000003125
EnsemblGenome_TRS: EBMYCT00000003127
EnsemblGenome_PRO: EBMYCP00000003127
EnsemblGenome: EBMYCG00000071373
EnsemblGenome_TRS: EBMYCT000000713
Taxonomy ID 83332
Gene Starting Position 4327548
Gene Ending Position 4328198
Gene Strand (Orientation) +
Protein Name TRANSCRIPTIONAL REGULATORY REPRESSOR PROTEIN (TETR-FAMILY) ETHR
DNA Sequence 
>gi|57116681:4327548-4328198 Mycobacterium tuberculosis H37Rv, complete genome
GGTGACCACCTCCGCGGCCAGTCAGGCTTCGCTGCCTAGGGGCCGGCGCACCGCGCGGCCGTCCGGCGAC
GATCGTGAACTGGCGATCCTCGCCACCGCCGAGAACCTTCTCGAGGACCGTCCGCTGGCCGATATCTCGG
TCGACGATCTGGCCAAGGGCGCCGGTATCTCGAGGCCGACGTTCTACTTCTATTTCCCATCCAAGGAAGC
GGTGCTGCTGACCCTGCTGGACCGGGTGGTCAATCAAGCCGACATGGCCCTACAGACCCTTGCCGAGAAT
CCCGCCGACACCGACCGCGAGAACATGTGGCGCACCGGGATCAACGTGTTCTTCGAGACATTCGGGTCGC
ACAAGGCGGTAACCCGAGCCGGTCAGGCCGCCAGGGCAACCAGTGTCGAAGTCGCCGAACTGTGGTCGAC
GTTTATGCAGAAGTGGATCGCCTACACGGCCGCCGTGATCGACGCCGAACGCGACCGAGGCGCGGCGCCG
CGCACCCTGCCGGCCCATGAACTGGCCACAGCGCTCAACCTGATGAACGAGCGGACGCTGTTCGCGTCAT
TCGCCGGCGAACAGCCCTCGGTGCCGGAAGCCCGCGTGCTGGATACGCTGGTGCACATCTGGGTGACCAG
CATTTACGGCGAGAACCGCTA
Protein Sequence 
>gi|15610991|ref|NP_218372.1| HTH-type transcriptional repressor EthR [Mycobacterium tuberculosis H37Rv] MTTSAASQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNQADMALQTLAENPADTDRENMWRTGINVFFETFGSHKAVTRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNERTLFASFAGEQPSVPEARVLDTLVHIWVTSIYGENR
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: attenuated in mice (Sassetti and Rubin, 2003).
COG COG1309K, under K: Transcription
References
Sassetti and Rubin, 2003: Sassetti CM, Rubin EJ. Genetic requirements for mycobacterial survival during infection. Proceedings of the National Academy of Sciences of the United States of America. 2003; 100(22); 12989-12994. [PubMed: 14569030].