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iucD from Shigella boydii Sb227

Victor ID 1575
Gene Name iucD from Shigella boydii Sb227
Sequence Strain (Species/Organism) Shigella boydii Sb227
NCBI Gene ID 3783323
NCBI Protein GI 82546637
Locus Tag SBO_4340
Protein Accession YP_410584.1
Other Database IDs UniProtKB-ID: Q31T52_SHIBS
UniRef100: UniRef100_Q31T52
UniRef90: UniRef90_P11295
UniRef50: UniRef50_P11295
UniParc: UPI00005E434E
EMBL: CP000036
EMBL-CDS: ABB68756.1
RefSeq_NT: NC_007613.1
EnsemblGenome: EBESCG00000075113.
EnsemblGenome_TRS: EBESCT00000076066
EnsemblGenome_PRO: EBESCP00000073213
GenomeReviews: CP000036_GR
KEGG: sbo:SBO_4340
HOGENOM: HBG415390
OMA: SAVYPES
ProtClustDB: CLSK888708
BioCyc: SBOY300268:SBO_4340-MONOMER
Taxonomy ID 300268
Gene Starting Position 4391012
Gene Ending Position 4392349
Gene Strand (Orientation) +
Protein Name lysine:N6-hydroxylase
DNA Sequence 
>gi|82542618:4391012-4392349 Shigella boydii Sb227, complete genome
CATGAAAAAAAGTGTCGATTTTATTGGTGTCGGGACAGGGCCATTTAATCTCAGCATTGCTGCATTGTCA
CATCAGATCGAAGAACTGAACTGTCTCTTCTTTGACGAACATCCTCATTTTTCCTGGCATCCGGGTATGC
TGGTACCGGATTGTCATATGCAGACCGTCTTTCTGAAAGATCTGGTCAGTGCAGTTGCACCTACAAATCC
CTACAGCTTTGTTAACTATCTGGTGAAGCACAAAAAGTTCTATCGCTTCCTTACAAGCAGGCTACGTACA
GTATCCCGTGAAGAGTTTTCTGACTATCTCCGCTGGGCTGCTGAAGATATGAATAACCTGTATTTCAGTC
ATACCGTTGAAAATATTGATTTCGACAAAAAAAGTCGATTGTTTCTGGTTCAGACCAGTCGGGGAGAATA
TTTTGCCCGCAATATCTGCCTTGGTACAGGAAAACAACCTTATTTACCACCCTGTGTGAAGCATGTGACA
CAATCCTGTTTCCATGCCAGTGAAATGAATCTTCGTCGGCCGGACCTGAGTGGAAAACGGATAACCGTGG
TTGGTGGAGGACAGAGTGGTGCAGACCTGTTCCTTAATGCATTACGCGGGGAATGGGGAGAAGCGGCGGA
AATAAACTGGGTCTCACGGCGTAATAATTTTAACGCACTGGATGAGGCTGCTTTTGCTGATGAGTATTTT
ACACCTGAATATATTTCAGGCTTCTCCGGACTGAAGGAAGATATTCGCCATCAGTTACTGGATGAGCAGA
AAATGACATCGGATGGCATCACTGCCGATTCTTTACTGACCATTTATCGTGAGTTGTACCACCGTTTTGA
AGTTCTGAGAAAACCAAGAAATATCCGTCTGCTACCCAGTCGCTCGGTAATAACTCTGGAAAGTAGTGGT
CCGGGCTGGAGGTTATTGATGGAACATCATCTGGATCAGGGCAGAGAGAGCCTGGAAAGTGATGTGGTGA
TTTTCGCCACAGGTTACCGTTCTGCATTGCCACAAATACTTCCCTCACTGATGCCCTTGATCACCATGCA
CGATAAGAACACCTTTAAAGTGCGTGATGACTTCACTCTGGAATGGAGTGGCCCGAAAGAAAATAACATC
TTTGCGGTCAACGCCAGCATGCAAACTCATGGCATCGCCGAACCCCAGCTCAGCCTGATGGCCTGGCGAT
CTGCACGTATTCTTAATCGCGTACTGGGGCGTGATTTATTCGATCTCAGTATGCCGCCCGCACTGATTCA
GTGGCGCAGCGGCAGCCGGAAAAAACCGCAGCCGGAGGCTGCTTCTTTAACTCACTATACAGCAAATATT
CAGGAATA
Protein Sequence 
>gi|82546637|ref|YP_410584.1| lysine:N6-hydroxylase [Shigella boydii Sb227] MKKSVDFIGVGTGPFNLSIAALSHQIEELNCLFFDEHPHFSWHPGMLVPDCHMQTVFLKDLVSAVAPTNPYSFVNYLVKHKKFYRFLTSRLRTVSREEFSDYLRWAAEDMNNLYFSHTVENIDFDKKSRLFLVQTSRGEYFARNICLGTGKQPYLPPCVKHVTQSCFHASEMNLRRPDLSGKRITVVGGGQSGADLFLNALRGEWGEAAEINWVSRRNNFNALDEAAFADEYFTPEYISGFSGLKEDIRHQLLDEQKMTSDGITADSLLTIYRELYHRFEVLRKPRNIRLLPSRSVITLESSGPGWRLLMEHHLDQGRESLESDVVIFATGYRSALPQILPSLMPLITMHDKNTFKVRDDFTLEWSGPKENNIFAVNASMQTHGIAEPQLSLMAWRSARILNRVLGRDLFDLSMPPALIQWRSGSRKKPQPEAASLTHYTANIQE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: iuc mutants are attenuated in chicken embryos and rabbit ileal loops (Wyckoff et al., 2009).
COG COG3486Q, under Q: Secondary metabolites biosynthesis, transport and catabolism
References
Wyckoff et al., 2009: Wyckoff EE, Boulette ML, Payne SM. Genetics and environmental regulation of Shigella iron transport systems. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine. 2009; 22(1); 43-51. [PubMed: 19130265].