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vacB from Shigella boydii Sb227

Victor ID 1569
Gene Name vacB from Shigella boydii Sb227
Sequence Strain (Species/Organism) Shigella boydii Sb227
NCBI Gene ID 3783260
NCBI Protein GI 161984790
Locus Tag SBO_4277
Protein Accession YP_410527.2
Other Database IDs UniProtKB-ID: Q31TA9_SHIBS
UniRef100: UniRef100_Q31TA9
UniRef90: UniRef90_P21499
UniRef50: UniRef50_P21499
UniParc: UPI00005E432E
EMBL: CP000036
EMBL-CDS: ABB68699.1
RefSeq_NT: NC_007613.1
EnsemblGenome: EBESCG00000077401.
EnsemblGenome_TRS: EBESCT00000078354
EnsemblGenome_PRO: EBESCP00000075501
GenomeReviews: CP000036_GR
KEGG: sbo:SBO_4277
HOGENOM: HBG690243
OMA: TTERMTY
ProtClustDB: PRK11642
BioCyc: SBOY300268:SBO_4277-MONOMER
Taxonomy ID 300268
Gene Starting Position 4325183
Gene Ending Position 4327624
Gene Strand (Orientation) -
Protein Name exoribonuclease R
DNA Sequence 
>gi|82542618:4325183-4327624 Shigella boydii Sb227, complete genome
ATCACTCTGCCACTTTTTTCTTCGCCGCACGCTTCGCTTTGGTCGCTGCAGCTATTTTCTGCGTTTTCGC
CGATGGCTTTTTCGCTTTTCTCGCGTCTTTCTTCGCTGCTTTCGGCTTCGTTTTTTTCTCACCGCGGAAG
GCGCTGTCTGGCTCAAAGTTTACCTTTTTACCGACCAGACGACGCTTGCCGCCTTTTTTACCTGCATCGC
CTTTTTTCGCTTTCTCGCGCGCCGTTTTACCGACGTTGCGCGGTGCGCGTTCGCTGGAGATCAGGCTAAA
GTCGATTTTGCGCTCGTCCATATTAACCGCTTCGACGCGAACTTCCACGCGATCGCCCAGACGATAAGTC
TGGCCGCTGGATTCACCCATCAGCCGTTGCCCTACCTGGTCAAAGCGATAGTAGTCATTGTCCAGCGAAG
AGACATGGACCAGACCATCAATGAATAAGTCGTCCAGACGGACAAAGAATCCAAAGCCAGTGACGCTGGA
AATTACGCCTTTAAAGACGTTACCTACCTGGTCGAGCATGAAGTCACACTTCAGCCAGTCAGCCACATCG
CGCGTTGCTTCGTCGGCACGACGTTCCGCCATCGAACAGTGCTGACCCAGTTGCAGCATTTCTTCCATCG
AATAATGGTAGCCGCCGGTTTCAGTGGTGTTGCCCTGATGCCCCTGCTCTTTCGCCAGCAGATATTTAAT
GGCGCGGTGCAGCGTCAGGTCTGGATAACGACGAATCGGCGAAGTAAAGTGCGCATAGGACTGCAATGCC
AGGCCAAAGTGACCACGGTTTTCTGGATCGTAAATCGCCTGTTTCATCGAGCGCAGCAGCATGGTTTGCA
GCATTTCTGCATCAGGACGATCGGCAACCGACTCCAGCAGCTCCGCGTAGTCACGCGGTTCCGGCTTGTT
ACCGCCCGGCAGTTCCAGCCCCAGCTCCGCCAGTACTGAACGGAAAGAGGTAATCGCTTCGGTGCTCGGC
TTGTCGTGAATACGGAACAATGCTGGTTCTTTGGCTTTCTCAACGAAACGCGCCGCCGAGATATTCGCCA
GAATCATGCACTCTTCAATTAACTTGTGTGCGTCGTTACGCTGAGTCTGTTCGATACGCTCAATACGGCA
TTCAGCGTTGAAAATAAACTTCGCTTCTTCGCTCTCAAATGAGATCCCGCCACGTTCTTCACGGGCTTTA
TCCAGCACTTTATAGAGGTTATGCAACTCTTCGAGATGCTTAACCAGCGGAGCGTACTGCTCGCGCAGAT
CCTGATCGCCCTGCAGAATATGCCAGACTTTGGTGTAGGTCAGACGCGCGTGAGAGCTCATCACCGCTTC
GTAGAATTTGTAGCCCGTCAGGCGGCCTTTCGACGAAACCGTCATCTCGCACACCATACACAGGCGGTCT
ACCTGCGGATTGAGCGAGCACAGACCGTTAGAGAGCACTTCCGGCAGCATAGGGATAACCTGCGAAGGGA
AGTACACCGACGTACCACGATTACGCGCTTCTCTATCCAGCGGCGTTGGCGGACGCACATAGTAGCTGAC
GTCGGCAATCGCGACCCATAAACGCCAGCCGCCGCCGCGTTTTTTCTCGCAGTAAACCGCATCGTCAAAG
TCACGGGCGTCTTCGCCATCAATGGTGACCAGCGGTAAATCGCGCAAATCGACACGGCCCGCTTTTGCTT
CTTCCGGCACTTCTTCTTTCAGCCCGGCAACCTGTTGCTCAACAGCCTGCGGCCAGATGTACGGAATTTC
ATGGGTACGCAAAGCGATATCAACCGCCATGCCGGTGCCCATATTGTCGCCCAGCACTTCGACGATTTTA
CCCACCGCTTTGGTACGGCGAGTCGGGCGTTGGGTCAGTTCAACAACCACCACAAAGCCCATCCGCGCGC
CCATGATCTGATCGGGCGGGATTAAGATATCGAAGCTCAGACGGCTATCGTCAGGAACCACAAAGCCGAC
GCCCGCTTCGGTAAAGTAGCGACCAACAATCTGGCTGGTTTTTGGCACCAGTACGCGGACAATACGCGCT
TCACGACGACCTTTACGGTCAGCACCCAGCGGCTGAGCCAGCACCTGATCGCCATGAATGCAGGTTTTCA
TCTGCTCGCTGGAGAGATACAAATCATCTTTACGCCCTTCAACCCGCAGAAAGCCGTAGCCATCACGGTG
GCCAATAACGGTACCTTTCACCAGGTCGAGGCGTTCCGGCAGCGCATAGCACTGACGACGAGTGAAGACC
AGTTGACCATCGCGCTCCATCGCGCGCAGGCGGCGACGCAGGCCTTCAAGCTGCTCTTCGCCTTCAATGT
GCAGTTCTACCGCCAGCTCATCACGGCTGGCCGGTTTTTCACGTTTGGTTAAATGTTCGAGGATAAATTC
CCGACTAGGGATGGGATTCGCGTATTTTTCAGCTTCGCGTTCCTGGAAAGGATCTTGTGACA
Protein Sequence 
>gi|161984790|ref|YP_410527.2| exoribonuclease R [Shigella boydii Sb227] MSQDPFQEREAEKYANPIPSREFILEHLTKREKPASRDELAVELHIEGEEQLEGLRRRLRAMERDGQLVFTRRQCYALPERLDLVKGTVIGHRDGYGFLRVEGRKDDLYLSSEQMKTCIHGDQVLAQPLGADRKGRREARIVRVLVPKTSQIVGRYFTEAGVGFVVPDDSRLSFDILIPPDQIMGARMGFVVVVELTQRPTRRTKAVGKIVEVLGDNMGTGMAVDIALRTHEIPYIWPQAVEQQVAGLKEEVPEEAKAGRVDLRDLPLVTIDGEDARDFDDAVYCEKKRGGGWRLWVAIADVSYYVRPPTPLDREARNRGTSVYFPSQVIPMLPEVLSNGLCSLNPQVDRLCMVCEMTVSSKGRLTGYKFYEAVMSSHARLTYTKVWHILQGDQDLREQYAPLVKHLEELHNLYKVLDKAREERGGISFESEEAKFIFNAECRIERIEQTQRNDAHKLIEECMILANISAARFVEKAKEPALFRIHDKPSTEAITSFRSVLAELGLELPGGNKPEPRDYAELLESVADRPDAEMLQTMLLRSMKQAIYDPENRGHFGLALQSYAHFTSPIRRYPDLTLHRAIKYLLAKEQGHQGNTTETGGYHYSMEEMLQLGQHCSMAERRADEATRDVADWLKCDFMLDQVGNVFKGVISSVTGFGFFVRLDDLFIDGLVHVSSLDNDYYRFDQVGQRLMGESSGQTYRLGDRVEVRVEAVNMDERKIDFSLISSERAPRNVGKTAREKAKKGDAGKKGGKRRLVGKKVNFEPDSAFRGEKKTKPKAAKKDARKAKKPSAKTQKIAAATKAKRAAKKKVAE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: vacB mutants had attenuated invasion of MK2 cells compared to the wild-type strain (Tobe et al., 1992).
COG COG0557K, under K: Transcription
References
Tobe et al., 1992: Tobe T, Sasakawa C, Okada N, Honma Y, Yoshikawa M. vacB, a novel chromosomal gene required for expression of virulence genes on the large plasmid of Shigella flexneri. Journal of bacteriology. 1992; 174(20); 6359-6367. [PubMed: 1400189].