Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

phoP from Shigella boydii Sb227

Victor ID 1560
Gene Name phoP from Shigella boydii Sb227
Sequence Strain (Species/Organism) Shigella boydii Sb227
NCBI Gene ID 3780892
NCBI Protein GI 82544383
Locus Tag SBO_1909
Protein Accession YP_408330.1
Other Database IDs UniProtKB-ID: Q31ZK6_SHIBS
UniRef100: UniRef100_Q8CXZ9
UniRef90: UniRef90_Q57QC3
UniRef50: UniRef50_Q5PMJ1
UniParc: UPI000000E0F8
EMBL: CP000036
EMBL-CDS: ABB66502.1
RefSeq_NT: NC_007613.1
EnsemblGenome: EBESCG00000076145.
EnsemblGenome_TRS: EBESCT00000077098
EnsemblGenome_PRO: EBESCP00000074245
GenomeReviews: CP000036_GR
KEGG: sbo:SBO_1909
HOGENOM: HBG753323
OMA: HIEEVVA
ProtClustDB: PRK10816
BioCyc: SBOY300268:SBO_1909-MONOMER
Taxonomy ID 300268
Gene Starting Position 1889211
Gene Ending Position 1889882
Gene Strand (Orientation) +
Protein Name DNA-binding response regulator in two-component regulatory system with PhoQ
DNA Sequence 
>gi|82542618:1889211-1889882 Shigella boydii Sb227, complete genome
AATGCGCGTACTGGTTGTTGAAGACAATGCGTTGTTACGTCACCACCTTAAAGTTCAGATTCAGGATGCT
GGTCATCAGGTCGATGATGCAGAAGATGCCAAAGAAGCCGATTATTATCTCAATGAACATTTACCGGATA
TTGCGATTGTCGATCTCGGATTGCCAGACGAGGACGGTCTGTCACTGATTCGCCGCTGGCGTAGCAATGA
TGTTTCACTGCCGATTCTGGTATTAACCGCCCGTGAAAGCTGGCAGGACAAAGTCGAAGTATTAAGTGCT
GGTGCTGATGATTACGTGACTAAACCATTTCATATTGAAGAGGTGATGGCGCGAATGCAGGCATTAATGC
GGCGTAATAGCGGTCTGGCTTCACAGGTCATTTCGCTACCACCGTTTCAGGTTGATCTCTCTCGCCGTGA
ATTATCTATTAATGACGAAGTGATCAAACTGACCGCGTTCGAATACACCATTATGGAAACGTTGATACGC
AATAATGGCAAAGTGGTGAGCAAAGATTCGTTAATGCTCCAACTCTATCCGGATGCGGAGCTGCGGGAAA
GCCATACCATTGATGTACTGATGGGACGTCTGCGCAAAAAAATTCAGGCACAATATCCGCAAGAAGTGAT
TACTACCGTTCGCGGCCAGGGCTATTTGTTCGAATTGCGCTG
Protein Sequence 
>gi|82544383|ref|YP_408330.1| DNA-binding transcriptional regulator PhoP [Shigella boydii Sb227] MRVLVVEDNALLRHHLKVQIQDAGHQVDDAEDAKEADYYLNEHLPDIAIVDLGLPDEDGLSLIRRWRSNDVSLPILVLTARESWQDKVEVLSAGADDYVTKPFHIEEVMARMQALMRRNSGLASQVISLPPFQVDLSRRELSINDEVIKLTAFEYTIMETLIRNNGKVVSKDSLMLQLYPDAELRESHTIDVLMGRLRKKIQAQYPQEVITTVRGQGYLFELR
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: phoP mutants were resolved more quickly than wild type in animal models, and are more susceptible to killing by PMNs (Moss et al., 2000).
COG COG0745TK, under T: Signal transduction mechanisms; K: Transcription
References
Moss et al., 2000: Moss JE, Fisher PE, Vick B, Groisman EA, Zychlinsky A. The regulatory protein PhoP controls susceptibility to the host inflammatory response in Shigella flexneri. Cellular microbiology. 2000; 2(6); 443-452. [PubMed: 11207599].