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aroD from Shigella boydii Sb227

Victor ID 1556
Gene Name aroD from Shigella boydii Sb227
Sequence Strain (Species/Organism) Shigella boydii Sb227
NCBI Gene ID 3780421
NCBI Protein GI 82543939
Locus Tag SBO_1438
Protein Accession YP_407886.1
Other Database IDs UniProtKB-ID: AROD_SHIBS
UniRef100: UniRef100_Q321F0
UniRef90: UniRef90_A7ZMF8
UniRef50: UniRef50_Q186A6
UniParc: UPI00005E3D5D
EMBL: CP000036
EMBL-CDS: ABB66058.1
RefSeq_NT: NC_007613.1
HSSP: Q9SQT8
EnsemblGenome: EBESCG00000077360
EnsemblGenome_TRS: EBESCT00000078313
EnsemblGenome_PRO: EBESCP00000075460
GenomeReviews: CP000036_GR
KEGG: sbo:SBO_1438
HOGENOM: HBG732926
OMA: NHDFDKT
ProtClustDB: PRK02412
BioCyc: SBOY300268:SBO_1438-MONOMER
Taxonomy ID 300268
Gene Starting Position 1414965
Gene Ending Position 1415723
Gene Strand (Orientation) -
Protein Name 3-dehydroquinate dehydratase
DNA Sequence 
>gi|82542618:1414965-1415723 Shigella boydii Sb227, complete genome
CTTATGCCTGATGTAAAATAGTTAATACTGTGCGTAAATCATTTACCGAGATTTGCCCTGGCGCAGAGGC
TTTTTTTACCGCACCAAAAGTTGCCGCCGAGCCAAATACTTCACCAGCCAGACGAGAAATTACGCCAGTT
TTTGCCATTGACATTGTGATGATTGGACGATCGGCATACTGCTCCTGCATCTCCAGGGTCGCGGCAAGCA
ACGTCAGCACATCGCTGGTACTTTGCGGCATCAGCGCAATCTTAGGAATATCGGCGTCGAAGGACTGCAT
TTTGCGCAGACGGGCAATGATTTCTTCGGCTTCCGGCGTTTTATGGAAGTCATGGTTGGACATGACAACT
TTCACATCATGCGCGTGGGCGCAGGCGACGGTTTCTTTAACCTGATCATCGCCGGTAAATAACTCCAGAT
CTATCATATCAACCAGGCCGCTGTCGATGGCTGCACGATTGAGAGCAATATAAGCCTCGGTGGAAATCGC
CTGCTCGCCGCCTTCTTTGGCACTGCGGAAGGTAAACAGCAGCGGTTTTTCTGGCATGGTTTCGCGGAGA
ATTTTTGCCGCCGCCATGACAGACTCCACATTGGAGAGGTCGGCAAAGTGGTCCACACGCCATTCCAGAA
TATCAAAGTCCGCTTCACGATAGGCGAGAGCTTCGGATTTCACGCGGGCGATATCTTTCGCCATCAGCGA
GACGATGATTTTAGGTGCGCCCGTACCAATGACGAGATCTTTTACAGTTACGGTTTTCA
Protein Sequence 
>gi|82543939|ref|YP_407886.1| 3-dehydroquinate dehydratase [Shigella boydii Sb227] MKTVTVKDLVIGTGAPKIIVSLMAKDIARVKSEALAYREADFDILEWRVDHFADLSNVESVMAAAKILRETMPEKPLLFTFRSAKEGGEQAISTEAYIALNRAAIDSGLVDMIDLELFTGDDQVKETVACAHAHDVKVVMSNHDFHKTPEAEEIIARLRKMQSFDADIPKIALMPQSTSDVLTLLAATLEMQEQYADRPIITMSMAKTGVISRLAGEVFGSAATFGAVKKASAPGQISVNDLRTVLTILHQA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: aroD deletion led to attenuation in HeLa cells and monkeys (Kärnell et al., 1993).
COG COG0710E, under E: Amino acid transport and metabolism
References
Kärnell et al., 1993: Kärnell A, Cam PD, Verma N, Lindberg AA. AroD deletion attenuates Shigella flexneri strain 2457T and makes it a safe and efficacious oral vaccine in monkeys. Vaccine. 1993; 11(8); 830-836. [PubMed: 8356844].