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ospD3 from Shigella boydii Sb227

Victor ID 1552
Gene Name ospD3 from Shigella boydii Sb227
Sequence Strain (Species/Organism) Shigella boydii Sb227
NCBI Gene ID 3776824
NCBI Protein GI 82524739
Locus Tag SBO_P076
Protein Accession YP_406300.1
Other Database IDs UniProtKB-ID: Q31SL0_SHIBS
UniRef100: UniRef100_Q31SL0
UniRef90: UniRef90_Q47634
UniRef50: UniRef50_Q47634
UniParc: UPI00005E43C1
EMBL: CP000037
EMBL-CDS: ABB68948.1
RefSeq_NT: NC_007608.1
EnsemblGenome: EBESCG00000079352.
EnsemblGenome_TRS: EBESCT00000080305
EnsemblGenome_PRO: EBESCP00000077286
GenomeReviews: CP000037_GR
KEGG: sbo:SBO_P076
HOGENOM: HBG683620
OMA: CERNNAN
ProtClustDB: CLSK504968
BioCyc: SBOY300268:SBO_P076-MONOMER
Taxonomy ID 300268
Plasmid No pSB4_227
Gene Starting Position 59601
Gene Ending Position 61298
Gene Strand (Orientation) -
Protein Name SenA; probably secreted by the Mxi-Spa secretion machinery
DNA Sequence 
>gi|82524664:59601-61298 Shigella boydii Sb227 plasmid pSB4_227, complete sequence
TTCAGCTTTTTATATTCTTCATAATTTCTAGAAAATCACTTCCATTTTTTTTGTCCAAGTGTTCTGCTAT
TTCTTCAGGTGTAATATTTTCATTTTTTATTATTCCCATATAAGTTTTTATTGCCTCAAAATTCCTATTT
TGAAAAGCTATAATTAATCCAGATACCCCATTTGGGCCTTCTGCCGCCAGTAATTTTGATGCCTGATGTG
GAGTAAGGTCTGCAGTGTGAAGTATTTTCCCATAAGCAATAATTGTTTCTACACATCCATTATGCAAGGC
TACAAACAATCCAGATAAACCATTAGAATCTTTCGCTTCTAACAGCTCTGCTTTTTTATCCAAGTTAAGT
TTTGCCTCATTCAAGATATCACCATAAGCTAAGATTGCATCAGCCTGTCCATTATTCAATGCTAACAGAA
GTCCGGGAACATTGTCATATCTCCTTGAGGCCAGCAAATTTACAATATCCTCTGAGTTGAGGAGAGGGGG
GCTAAGAATGAGCTCACCGTATGCGCGTATAGCATCTGCATGTCCATTTTGAAGAGCAAACATTAGTCCG
GGTATCTGTCTGTGTACTTCATCATAATAATAAGCGGTCAGCAAATTTTTCAGCTTATTGTATTCGATAT
TTATTGCTCTCTTCTTGAGAAGCCTTCCGTATGTTTTGATAGTTTCTGCATGCCCATTTTGAAGTGCTTG
GGATAAACCCGATATTCGTCCTCCCATTCCTTCCGCAGTTAGTAGTTCTACCGTTTTATCAAGGTTAAGT
CCAGAAGTTTCCAGGAGTTCTCCGTATGCTAAGATTGTATCTGAATGCCCATTTTGTAAAGCTAAAAGCA
ATCCTGACAAACCATCGTCATTTTTGGCTGCCAAAAGTAATTCTAACGTATTGTCTGAAAGGTCAGATAG
TTGTACGACTCTTGTTACTTTTTGGATTAGCTCAGTCAATCCCATACGCATCGCGTGATAAATAACTTTG
GGGTGAAGTAAATTATTAGGCCATCTGATTATGGAGGACATGCTTGTTGGAGTATGTCTGTCCACAAATA
TAGACATACCGTCGGATATAAGACCATAACATTTCTGATGTTTTTCATCAAGAAAATTATCTACAGTCAG
TTTTTTTATTTTAGCTAAGTTAAATTTGTTAAACTCTGCTCGTAAATGAGTTGCTGTATGGTTGGGATCA
TAAAGCTGAATGACAAAATCCCCCCCATTTTTAGTTTCTTTAATCTTCAAGCCTAATGCCATATTGTGAT
TTGATGTACTTATTTCTAGTGCTCTGCTTTTTTCGGAATGAAAAATCATTTCATTGAAAATATAAAAAAT
AATATCTCCCCATGAACCGTTTTCAACAAAATAAATAATAGCAGGCACATTAATAGCCTTTTCTTCTTCA
CTCACTGAAACATAATTTTTAATTTCATCCGGAAAAGCAAAGTGATGATAATCCACGTGACCACTACTTT
TGTTAAACTGTGCTATCCAGTAGGAAGCTAAGTGTCGACAGACAATAAGTTTTCCAGAGTGATCGGTAAC
TTGGCAATTTAGATTTAATAAAAAACTCCTCTTGTCAGAAAAATATGGCAATTGTTTTGAGTGCAATAGA
GACTGGATTGTCTCAACAGAGACGTTGTCTTTATTTATCATATTTTGCAAACATATTTTCCTTGATGGGA
TTAAATTTACTGATGGCA
Protein Sequence 
>gi|82524739|ref|YP_406300.1| OspD3 [Shigella boydii Sb227] MPSVNLIPSRKICLQNMINKDNVSVETIQSLLHSKQLPYFSDKRSFLLNLNCQVTDHSGKLIVCRHLASYWIAQFNKSSGHVDYHHFAFPDEIKNYVSVSEEEKAINVPAIIYFVENGSWGDIIFYIFNEMIFHSEKSRALEISTSNHNMALGLKIKETKNGGDFVIQLYDPNHTATHLRAEFNKFNLAKIKKLTVDNFLDEKHQKCYGLISDGMSIFVDRHTPTSMSSIIRWPNNLLHPKVIYHAMRMGLTELIQKVTRVVQLSDLSDNTLELLLAAKNDDGLSGLLLALQNGHSDTILAYGELLETSGLNLDKTVELLTAEGMGGRISGLSQALQNGHAETIKTYGRLLKKRAINIEYNKLKNLLTAYYYDEVHRQIPGLMFALQNGHADAIRAYGELILSPPLLNSEDIVNLLASRRYDNVPGLLLALNNGQADAILAYGDILNEAKLNLDKKAELLEAKDSNGLSGLFVALHNGCVETIIAYGKILHTADLTPHQASKLLAAEGPNGVSGLIIAFQNRNFEAIKTYMGIIKNENITPEEIAEHLDKKNGSDFLEIMKNIKS
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: sen deletion mutant elicited lower rises in mucosal short-circuit current than the wild type, suggesting that the senA/ospD3 gene encodes an enterotoxin of Shigella (Nataro et al., 1995).
References
Nataro et al., 1995: Nataro JP, Seriwatana J, Fasano A, Maneval DR, Guers LD, Noriega F, Dubovsky F, Levine MM, Morris JG Jr. Identification and cloning of a novel plasmid-encoded enterotoxin of enteroinvasive Escherichia coli and Shigella strains. Infection and immunity. 1995; 63(12); 4721-4728. [PubMed: 7591128].