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virF from Shigella boydii Sb227

Victor ID 1550
Gene Name virF from Shigella boydii Sb227
Sequence Strain (Species/Organism) Shigella boydii Sb227
NCBI Gene ID 3776800
NCBI Protein GI 82524715
Locus Tag SBO_P052
Protein Accession YP_406276.1
Other Database IDs UniProtKB-ID: Q31SN4_SHIBS
UniRef100: UniRef100_P0A2T2
UniRef90: UniRef90_P0A2T2
UniRef50: UniRef50_P0A2T2
UniParc: UPI0000138851
EMBL: CP000037
EMBL-CDS: ABB68924.1
RefSeq_NT: NC_007608.1
EnsemblGenome: EBESCG00000079393.
EnsemblGenome_TRS: EBESCT00000080346
EnsemblGenome_PRO: EBESCP00000077327
GenomeReviews: CP000037_GR
KEGG: sbo:SBO_P052
HOGENOM: HBG674032
OMA: AVVEIEY
ProtClustDB: CLSK542186
BioCyc: SBOY300268:SBO_P052-MONOMER
Taxonomy ID 300268
Plasmid No pSB4_227
Gene Starting Position 38538
Gene Ending Position 39326
Gene Strand (Orientation) +
Protein Name member of the AraC family of transcriptional activators; required for transcription of virB and icsA
DNA Sequence 
>gi|82524664:38538-39326 Shigella boydii Sb227 plasmid pSB4_227, complete sequence
TATGATGGATATGGGACATAAAAACAAAATAGATATAAAGGTTCGCTTGCATAACTATATTATTTTATAT
GCAAAAAGGTGTTCAATGACGGTTAGCTCAGGCAATGAAACTTTGACTATCGATGAAGGGCAAATTGCTT
TTATAGAGCGAAATATACAAATAAACGTCTCCATAAAAAAATCTGATAGCATTAATCCATTTGAGATTAT
AAGCCTTGACAGAAATTTATTATTAAGCATTATTAGAATAATGGAACCAATTTATTCATTTCAACACTCC
TATTCTGAGGAGAAAAGGGGGTTAAACAAAAAAATATTCCTCCTCTCTGAGGAGGAGGTTTCTATCGATT
TGTTCAAATCTATAAAAGAGATGCCTTTTGGCAAAAGAAAGATCTATAGTTTAGCTTGCCTTTTATCAGC
TGTTTCTGATGAGGAAGCTTTATATACTTCGATATCGATAGCTTCTTCTCTTAGTTTTTCTGATCAGATA
AGGAAGATTGTTGAAAAAAACATCGAGAAGAGATGGCGTCTTTCTGATATTTCAAATAACTTGAATTTAT
CAGAAATAGCTGTTAGAAAACGATTGGAGAGTGAAAAATTAACATTTCAACAAATCCTTCTTGATATTCG
CATGCATCATGCAGCAAAGCTTTTATTGAATAGTCAAAGCTATATTAATGATGTATCAAGACTTATCGGA
ATATCAAGCCCATCTTATTTTATAAGGAAATTTAATGAATATTATGGTATAACTCCAAAGAAATTTTACT
TATATCATAAAAAATTTTA
Protein Sequence 
>gi|82524715|ref|YP_406276.1| VirF [Shigella boydii Sb227] MMDMGHKNKIDIKVRLHNYIILYAKRCSMTVSSGNETLTIDEGQIAFIERNIQINVSIKKSDSINPFEIISLDRNLLLSIIRIMEPIYSFQHSYSEEKRGLNKKIFLLSEEEVSIDLFKSIKEMPFGKRKIYSLACLLSAVSDEEALYTSISIASSLSFSDQIRKIVEKNIEKRWRLSDISNNLNLSEIAVRKRLESEKLTFQQILLDIRMHHAAKLLLNSQSYINDVSRLIGISSPSYFIRKFNEYYGITPKKFYLYHKKF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: virF knockouts are non-invasive to host cells (Hurt et al., 2010).
COG COG2207K, under K: Transcription
References
Hurt et al., 2010: Hurt JK, McQuade TJ, Emanuele A, Larsen MJ, Garcia GA. High-throughput screening of the virulence regulator VirF: a novel antibacterial target for shigellosis. Journal of biomolecular screening : the official journal of the Society for Biomolecular Screening. 2010; 15(4); 379-387. [PubMed: 20237205].