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ospF from Shigella boydii Sb227

Victor ID 1548
Gene Name ospF from Shigella boydii Sb227
Sequence Strain (Species/Organism) Shigella boydii Sb227
NCBI Gene ID 3776764
NCBI Protein GI 82524680
Locus Tag SBO_P017
Protein Accession YP_406241.1
Other Database IDs UniProtKB-ID: OSPF_SHIBS
UniRef100: UniRef100_Q31SR9
UniRef90: UniRef90_Q31SR9
UniRef50: UniRef50_Q327I2
UniParc: UPI00001D8F96
EMBL: CP000037
EMBL-CDS: ABB68889.1
RefSeq_NT: NC_007608.1
EnsemblGenome: EBESCG00000079386
EnsemblGenome_TRS: EBESCT00000080339
EnsemblGenome_PRO: EBESCP00000077320
GenomeReviews: CP000037_GR
KEGG: sbo:SBO_P017
HOGENOM: HBG673220
OMA: ESDVHPE
ProtClustDB: CLSK862802
BioCyc: SBOY300268:SBO_P017-MONOMER
Taxonomy ID 300268
Plasmid No pSB4_227
Gene Starting Position 11926
Gene Ending Position 12645
Gene Strand (Orientation) -
Protein Name OspF
DNA Sequence 
>gi|82524664:11926-12645 Shigella boydii Sb227 plasmid pSB4_227, complete sequence
TCTACTCTATCATCAAACGATAAAATGGTTCCTCTCGTAACATTTGCTCTTGCCTTTCACTTCCATCTCG
ATCGCTTCGTAGTTCATTACGATAGCTGACATATTTCCAGTCTTCAGGTCTAACATCTGACGCCGGATAC
TCCCCGGGAGCGATTTTGCTTCTTAATAGATTAGACTCGAGACACATTATAAATTGTCGTATTTTATGAA
GTAATAAAGCACTATATTGCGAGCATTCCTGATCTGATTTTACATATAGCGTAAACTGAGCTCCTATCCC
CACACGAGATTGCTGAGAAACTCGATTCATATCAGTTATCTTCCATTTATCTATAGGACTGTCCTCTGAA
AATAATAAACCAGACAAAATTTGGAATGCCAGAGGAACTTGCTCCCTAGCTATACTAATATGAAACTTGT
CCCCAACAAAATCCCCCTTACTCTGAGGATTTTCACGACATGCATGAATAAACACATCTCCACTATGGTT
CACAATCTGGAATCCTTGGTACATGACAGAAAAAAATTGACATATATCAGAGTAAGTTGGCACGTTCGAT
GCTACTTTGAAATAGTACGCTGGGTATTGCCGTATTTGGTTGTACAATATATTGAAGTTATTTTTCAATC
TTTCATTCGCAGAAAGCATCTGCGGTATTTCAGACCTCACAACATTCAAAGAATCTAAATTTAGTTTTAG
ACAGGGCTTTTTTATGGGCA
Protein Sequence 
>gi|82524680|ref|YP_406241.1| OspF [Shigella boydii Sb227] MPIKKPCLKLNLDSLNVVRSEIPQMLSANERLKNNFNILYNQIRQYPAYYFKVASNVPTYSDICQFFSVMYQGFQIVNHSGDVFIHACRENPQSKGDFVGDKFHISIAREQVPLAFQILSGLLFSEDSPIDKWKITDMNRVSQQSRVGIGAQFTLYVKSDQECSQYSALLLHKIRQFIMCLESNLLRSKIAPGEYPASDVRPEDWKYVSYRNELRSDRDGSERQEQMLREEPFYRLMIE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: ospF mutants had reduced PMN transepithelial migration when compared to wild-type infection, PMN transepithelial migration is necessary for virulence of Shigella (Zurawski et al., 2006).
References
Zurawski et al., 2006: Zurawski DV, Mitsuhata C, Mumy KL, McCormick BA, Maurelli AT. OspF and OspC1 are Shigella flexneri type III secretion system effectors that are required for postinvasion aspects of virulence. Infection and immunity. 2006; 74(10); 5964-5976. [PubMed: 16988276].