Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

guaB from Shigella dysenteriae Sd197

Victor ID 1540
Gene Name guaB from Shigella dysenteriae Sd197
Sequence Strain (Species/Organism) Shigella dysenteriae Sd197
NCBI Gene ID 3798806
Uniprot ID Q32D54
NCBI Protein GI 82777893
Locus Tag SDY_2704
Protein Accession YP_404242.1
Other Database IDs UniProtKB-ID: Q32D54_SHIDS
UniRef100: UniRef100_Q32D54
UniRef90: UniRef90_P0ADG8
UniRef50: UniRef50_O50316
UniParc: UPI00005E3548
EMBL: CP000034
EMBL-CDS: ABB62751.1
RefSeq_NT: NC_007606.1
EnsemblGenome: EBESCG00000080675.
EnsemblGenome_TRS: EBESCT00000081629
EnsemblGenome_PRO: EBESCP00000078609
GenomeReviews: CP000034_GR
KEGG: sdy:SDY_2704
NMPDR: fig|216598.1.peg.1264
eggNOG: COG0516
HOGENOM: HBG298985
OMA: CVGLITV
ProtClustDB: PRK05567
BioCyc: SDYS300267:SDY_2704-MONOMER
Taxonomy ID 300267
Gene Starting Position 2495882
Gene Ending Position 2497348
Gene Strand (Orientation) -
Protein Name inositol-5-monophosphate dehydrogenase
DNA Sequence 
>gi|82775382:2495882-2497348 Shigella dysenteriae Sd197, complete genome
ATCAGGAGCCCAGACGGTAGTTCGGGGACTCTTTAGTAATGGTCACGTCGTGAACGTGGCTTTCCTGAAT
GCCCGCACCGCTGATACGTACAAACTCCGCTTTAGTACGCAGTTCGTCGATAGTACCACAGCCGGTCAGA
CCCATACAGGAGCGCAGGCCGCCCATCTGCTGGTGAATGATCTCTTTCAGGCGACCTTTATAAGCTACGC
GACCTTCGATACCTTCCGGCACCAGTTTGTCGGCAGCGTTATCGCTCTGGAAATAACGGTCAGAGGAACC
TTTGGACATCGCGCCCAGGGAACCCATCCCACGGTAAGATTTGTAAGAACGGCCCTGGTAGAGTTCGATT
TCACCCGGAGATTCTTCAGTACCTGCCAGCATGGAACCTACCATCACCGCGCTTGCGCCAGCGGCGATAG
CTTTGGCGATGTCGCCGGAGAAGCGAATACCACCATCTGCGATAACCGGAATACCGGTGCCTTCCAGGGC
TTCAACTGCGTCAGCAACGGCAGTGATCTGCGGAACACCTACGCCAGTAACGATACGAGTCGTACAGATA
GAACCAGGGCCGATACCGACTTTAACCGCGCTGCAACCAGCTTCTGCCAGAGCGCGTGCACCTGCAGCTG
TTGCCACGTTGCCGCCGATGATTTGCAGATCCGGATATTTAGCACGGGTTTCACGGATACGCTGCAAAAC
GCCTTCTGAGTGACCGTGGGAGGAGTCGATCAGCAGAACGTCAACGCCAGCGGCAACCAGCGCGTCAACA
CGCTCTTCGTTACCCGCACCTGCGCCAACTGCAGCACCAACACGCAGACGGCCTTGCTCGTCTTTACAGG
CGTTCGGTTTACGTTCCGCTTTCTGGAAATCTTTCACGGTGATCATGCCGATCAGGTGGAATTCGTCATC
AACCACCAGCGCTTTTTCAACGCGTTTTTCGTGCATTTTTGCCAGCACCACTTCACGGGCTTCACCTTCA
CGCACGGTGACCAGACGCTCTTTCGGCGTCATGTAAACGCTAACCGGCTGGTTCAGGTCGGTAACAAAAC
GCACGTCACGACCGGTGATAATACCCTCTAGTTCGTTTTCTTCGGTAACGACCGGATAGCCCGCAAAACC
GTTACGCTCGGTCAGTTCTTTCACTTCGCGCAGCGTCGTGGTTGGCAGAACAGTCTGCGGATCAGTCACC
ACACCAGATTCGTGTTTTTTCACACGGCGAACTTCTTCTGCCTGGCGTTCAATGGACATGTTTTTGTGGA
TAAAGCCGATACCGCCTTCCTGAGCCAGAGCAATAGCCAGGCGCGCTTCCGTTACGGTATCCATTGCTGC
GGAAAGCATAGGGATATTCAGACGAATAGTTTTCGTCAGCTGGGTGCTGAGGTCAGCAGTATTCGGCAGA
ACGGTAGAATGAGCAGGAACGAGGAGAACGTCGTCAAACGTCAGAGCTTCTTTAGCGATACGTAGCA
Protein Sequence 
>gi|82777893|ref|YP_404242.1| inosine 5'-monophosphate dehydrogenase [Shigella dysenteriae Sd197] MLRIAKEALTFDDVLLVPAHSTVLPNTADLSTQLTKTIRLNIPMLSAAMDTVTEARLAIALAQEGGIGFIHKNMSIERQAEEVRRVKKHESGVVTDPQTVLPTTTLREVKELTERNGFAGYPVVTEENELEGIITGRDVRFVTDLNQPVSVYMTPKERLVTVREGEAREVVLAKMHEKRVEKALVVDDEFHLIGMITVKDFQKAERKPNACKDEQGRLRVGAAVGAGAGNEERVDALVAAGVDVLLIDSSHGHSEGVLQRIRETRAKYPDLQIIGGNVATAAGARALAEAGCSAVKVGIGPGSICTTRIVTGVGVPQITAVADAVEALEGTGIPVIADGGIRFSGDIAKAIAAGASAVMVGSMLAGTEESPGEIELYQGRSYKSYRGMGSLGAMSKGSSDRYFQSDNAADKLVPEGIEGRVAYKGRLKEIIHQQMGGLRSCMGLTGCGTIDELRTKAEFVRISGAGIQESHVHDVTITKESPNYRLGS
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: guaAguaB mutants are attenuated in HeLa cells (Noriega et al., 1996).
Predicted Interacting Host Protein A1L3W5; B0LPE5; B3KVH4; P31749; Q6EEV6; Q8N2W9; Q9NRR5
COG COG0516F, under F: Nucleotide transport and metabolism
References
Noriega et al., 1996: Noriega FR, Losonsky G, Lauderbaugh C, Liao FM, Wang JY, Levine MM. Engineered deltaguaB-A deltavirG Shigella flexneri 2a strain CVD 1205: construction, safety, immunogenicity, and potential efficacy as a mucosal vaccine. Infection and immunity. 1996; 64(8); 3055-3061. [PubMed: 8757833].