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Rv3869

Victor ID 154
Gene Name Rv3869
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 886166
NCBI Protein GI 15611005
Locus Tag Rv3869
Protein Accession NP_218386.1
Other Database IDs UniProtKB-ID: ECCB1_MYCTU
UniRef100: UniRef100_O69734
UniRef90: UniRef90_O69734
UniRef50: UniRef50_O69734
UniParc: UPI00000D1163
EMBL: BX842584
EMBL: AE000516
EMBL-CDS: CAA17961.1
EMBL-CDS: AAK48350.1
RefSeq_NT: NC_000962.2
RefSeq_NT: NC_002755.2
EnsemblGenome: EBMYCG00000003943
EnsemblGenome_TRS: EBMYCT00000003945
EnsemblGenome_PRO: EBMYCP00000003945
EnsemblGenome: EBMYCG00000072933
EnsemblGenome_TRS: EBMYCT00000072938
EnsemblGenome_PRO: EBMYCP00000070997
GenomeReviews: AE000516_GR
GenomeReview
Taxonomy ID 83332
Gene Starting Position 4345038
Gene Ending Position 4346480
Gene Strand (Orientation) +
Protein Name POSSIBLE CONSERVED MEMBRANE PROTEIN
DNA Sequence 
>gi|57116681:4345038-4346480 Mycobacterium tuberculosis H37Rv, complete genome
TATGGGGCTTCGCCTCACCACCAAGGTTCAGGTTAGCGGCTGGCGTTTTCTGCTGCGCCGGCTCGAACAC
GCCATCGTGCGCCGGGACACCCGGATGTTTGACGACCCGCTGCAGTTCTACAGCCGCTCGATCGCTCTTG
GCATCGTCGTCGCGGTCCTGATTCTGGCGGGTGCCGCGCTGCTGGCGTACTTCAAACCACAAGGCAAACT
CGGCGGCACCAGCCTGTTCACCGACCGCGCGACCAACCAGCTTTACGTGCTGCTGTCCGGACAGTTGCAT
CCGGTCTACAACCTGACTTCGGCGCGGCTGGTGCTGGGCAATCCGGCCAACCCGGCCACCGTGAAGTCCT
CCGAACTGAGCAAGCTGCCGATGGGCCAGACCGTTGGAATCCCCGGCGCCCCCTACGCCACGCCTGTTTC
GGCGGGCAGCACCTCGATCTGGACCCTATGCGACACCGTCGCCCGAGCCGACTCCACTTCCCCGGTAGTG
CAGACCGCGGTCATCGCGATGCCGTTGGAGATCGATGCTTCGATCGATCCGCTCCAGTCACACGAAGCGG
TGCTGGTGTCCTACCAGGGCGAAACCTGGATCGTCACAACTAAGGGACGCCACGCCATAGATCTGACCGA
CCGCGCCCTCACCTCGTCGATGGGGATACCGGTGACGGCCAGGCCAACCCCGATCTCGGAGGGCATGTTC
AACGCGCTGCCTGATATGGGGCCCTGGCAGCTGCCGCCGATACCGGCGGCGGGCGCGCCCAATTCGCTTG
GCCTACCTGATGATCTAGTGATCGGATCGGTCTTCCAGATCCACACCGACAAGGGCCCGCAATACTATGT
GGTGCTGCCCGACGGCATCGCGCAGGTCAACGCGACAACCGCTGCGGCGCTGCGCGCCACCCAGGCGCAC
GGGCTGGTCGCGCCACCGGCAATGGTGCCCAGTCTGGTCGTCAGAATCGCCGAACGGGTATACCCCTCAC
CGCTACCCGATGAACCGCTCAAGATCGTGTCCCGGCCGCAGGATCCCGCGCTGTGCTGGTCATGGCAACG
CAGCGCCGGCGACCAGTCGCCGCAGTCAACGGTGCTGTCCGGCCGGCATCTGCCGATATCGCCCTCAGCG
ATGAACATGGGGATCAAGCAGATCCACGGGACGGCGACCGTTTACCTCGACGGCGGAAAATTCGTGGCAC
TGCAATCCCCCGATCCTCGATACACCGAATCGATGTACTACATCGATCCACAGGGCGTGCGTTATGGGGT
GCCTAACGCGGAGACAGCCAAGTCGCTGGGCCTGAGTTCACCCCAAAACGCGCCCTGGGAGATCGTTCGT
CTCCTGGTCGACGGTCCGGTGCTGTCGAAAGATGCCGCACTGCTCGAGCACGACACGCTGCCCGCTGACC
CTAGCCCCCGAAAAGTTCCCGCCGGAGCCTCCGGAGCCCCCTG
Protein Sequence 
>gi|15611005|ref|NP_218386.1| ESX-1 secretion system protein EccB [Mycobacterium tuberculosis H37Rv] MGLRLTTKVQVSGWRFLLRRLEHAIVRRDTRMFDDPLQFYSRSIALGIVVAVLILAGAALLAYFKPQGKLGGTSLFTDRATNQLYVLLSGQLHPVYNLTSARLVLGNPANPATVKSSELSKLPMGQTVGIPGAPYATPVSAGSTSIWTLCDTVARADSTSPVVQTAVIAMPLEIDASIDPLQSHEAVLVSYQGETWIVTTKGRHAIDLTDRALTSSMGIPVTARPTPISEGMFNALPDMGPWQLPPIPAAGAPNSLGLPDDLVIGSVFQIHTDKGPQYYVVLPDGIAQVNATTAAALRATQAHGLVAPPAMVPSLVVRIAERVYPSPLPDEPLKIVSRPQDPALCWSWQRSAGDQSPQSTVLSGRHLPISPSAMNMGIKQIHGTATVYLDGGKFVALQSPDPRYTESMYYIDPQGVRYGVPNAETAKSLGLSSPQNAPWEIVRLLVDGPVLSKDAALLEHDTLPADPSPRKVPAGASGAP
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: attenuated in mice (Sassetti and Rubin, 2003).
References
Sassetti and Rubin, 2003: Sassetti CM, Rubin EJ. Genetic requirements for mycobacterial survival during infection. Proceedings of the National Academy of Sciences of the United States of America. 2003; 100(22); 12989-12994. [PubMed: 14569030].