Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

aroD from Shigella dysenteriae Sd197

Victor ID 1536
Gene Name aroD from Shigella dysenteriae Sd197
Sequence Strain (Species/Organism) Shigella dysenteriae Sd197
NCBI Gene ID 3797994
NCBI Protein GI 82776755
Locus Tag SDY_1474
Protein Accession YP_403104.1
Other Database IDs UniProtKB-ID: AROD_SHIDS
UniRef100: UniRef100_Q32GE2
UniRef90: UniRef90_A7ZMF8
UniRef50: UniRef50_Q186A6
UniParc: UPI00005E3236
EMBL: CP000034
EMBL-CDS: ABB61613.1
RefSeq_NT: NC_007606.1
HSSP: Q9SQT8
EnsemblGenome: EBESCG00000079656
EnsemblGenome_TRS: EBESCT00000080609
EnsemblGenome_PRO: EBESCP00000077589
GenomeReviews: CP000034_GR
KEGG: sdy:SDY_1474
NMPDR: fig|216598.1.peg.798
eggNOG: COG0710
HOGENOM: HBG732926
OMA: NHDFDKT
ProtClustDB: PRK02412
BioCyc: SDYS300267:SDY_1474-MONOMER
Taxonomy ID 300267
Gene Starting Position 1354382
Gene Ending Position 1355140
Gene Strand (Orientation) -
Protein Name 3-dehydroquinate dehydratase
DNA Sequence 
>gi|82775382:1354382-1355140 Shigella dysenteriae Sd197, complete genome
CTTATGCCTGATGTAAAATAGTTAATACTGTGCGCAAATCATTTACCGAGATTTGCCCTGGCGCAGAGGC
TTTTTTTACCGCACCAAAAGTTGCCGCCGAGCCAAATACTTCACCAGCCAGACGAGAAATTACGCCAGTT
TTTGCCATTGACATCGTGATGATTGGACGATCGGCATACTGCTCCTGCATCTCCAGGGTCGCGGCAAGCA
ACGTCAGCACATCGCTGGTACTTTGCGGCATCAGCGCAATCTTAGGAATATCGGCGTCGAAGGACTGCAT
TTTGCGCAGACGGGCAATGATTTCTTCGGCTTCCGGCGTTTTATGGAAGTCATGGTTGGACATGACAACT
TTCACATCATGCGCGTGGGCGTAGGCGACGGTTTCTTTAACCTGATCATCGCCGGTAAATAACTCCAGAT
CGATCATATCAACCAGGCCGCTGTCGATGGCTGCACGATTGAGAGCAATATAAGCCTCGGTGGAAATCGC
CTGCTCGCCGCCTTCTTTGGCACTGCGGAAGGTAAACAGCAGCGGTTTTTCTGGCATGGTTTCACGGAGA
ATTTTTGCCGCCGCCATGACAGACTCCACATTGGAGAGGTCGGCAAAGTGGTCCACACGCCATTCCAGAA
TATCAAAGTCCGTTTCACGATAGGCGAGAGCTTCGGATTTCACGCGGGCGATATCTTTCGCCATCAGCGA
GACGATGATTTTAGGTGCGCCCGCACCAATGACGAGATCTTTTACAGTTACGGTTTTCA
Protein Sequence 
>gi|82776755|ref|YP_403104.1| 3-dehydroquinate dehydratase [Shigella dysenteriae Sd197] MKTVTVKDLVIGAGAPKIIVSLMAKDIARVKSEALAYRETDFDILEWRVDHFADLSNVESVMAAAKILRETMPEKPLLFTFRSAKEGGEQAISTEAYIALNRAAIDSGLVDMIDLELFTGDDQVKETVAYAHAHDVKVVMSNHDFHKTPEAEEIIARLRKMQSFDADIPKIALMPQSTSDVLTLLAATLEMQEQYADRPIITMSMAKTGVISRLAGEVFGSAATFGAVKKASAPGQISVNDLRTVLTILHQA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: aroD deletion led to attenuation in HeLa cells and monkeys (Kärnell et al., 1993).
COG COG0710E, under E: Amino acid transport and metabolism
References
Kärnell et al., 1993: Kärnell A, Cam PD, Verma N, Lindberg AA. AroD deletion attenuates Shigella flexneri strain 2457T and makes it a safe and efficacious oral vaccine in monkeys. Vaccine. 1993; 11(8); 830-836. [PubMed: 8356844].