Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

miaA from Shigella dysenteriae Sd197

Victor ID 1535
Gene Name miaA from Shigella dysenteriae Sd197
Sequence Strain (Species/Organism) Shigella dysenteriae Sd197
NCBI Gene ID 3797380
NCBI Protein GI 82779447
Locus Tag SDY_4418
Protein Accession YP_405796.1
Other Database IDs UniProtKB-ID: MIAA_SHIDS
UniRef100: UniRef100_Q328F0
UniRef90: UniRef90_A8AMN0
UniRef50: UniRef50_Q7U347
UniParc: UPI00005E391E
EMBL: CP000034
EMBL-CDS: ABB64305.1
RefSeq_NT: NC_007606.1
EnsemblGenome: EBESCG00000083218
EnsemblGenome_TRS: EBESCT00000084172
EnsemblGenome_PRO: EBESCP00000081152
GenomeReviews: CP000034_GR
KEGG: sdy:SDY_4418
eggNOG: COG0324
HOGENOM: HBG559459
OMA: VNADSMQ
ProtClustDB: PRK00091
BioCyc: SDYS300267:SDY_4418-MONOMER
Taxonomy ID 300267
Gene Starting Position 4133624
Gene Ending Position 4134574
Gene Strand (Orientation) -
Protein Name tRNA delta(2)-isopentenylpyrophosphate transferase
DNA Sequence 
>gi|82775382:4133624-4134574 Shigella dysenteriae Sd197, complete genome
TTCAGCCTGCGATAGCACCAACAACCTGTAATACTTCGTCACGCGCCTGTTCTGGTTTTTCACTATCAAG
CCAGTGAACCCCTTCCCAACCACGCAGCCAGGTTATCTGCCGCTTCGCCAACTGTCTCGTGGCGCAAACA
CCTAGATAAACCATTTCATCGTATGAGATTTCGCCTTCAAGGTAAGACCACATCTGGCGATAACCCACGC
AACGAATGGAAGGCAAGTCCGTATGCAAATCTCCTCGGGCAAAAAGCGCCCGGACTTCTGCTTCAAAACC
TGAAGCCAACATCTGATGAAAACGCTGCTCAATGCGTTGATGGAGCAGTTCACGGCTCGCCGGGGCGATG
GCGAACTGATGCACCTGATACGGTAGAGCGTCTCCTGACGTTTGCGTCAGTTCCGTTAAAGTTTTACCCG
AAATGAAAAAAACTTCCAGTGCCCGGGAAAGCCTTTGTGGATCATTTGGATGAATCCTTGCTGCCGCAAC
CGGATCTACCTCCTGAAGTTGACGATGCAATGACTCCCAACCTTGCTCTGCCGCCTGTTGCTCAATTCTG
GCCCGTACTTCCGGGTCTGCCGACGGTAGCGGCGACAACCCTTCCAGCAATGCCTTGAAATACAACATCG
TACCGCCCACTAACAGTGGGATCCGCCCCGCCGCGGTGATATCGGCCATTTCCGCCAGCGCATCGCGGCG
AAAATCAGCAGCCGAGTAAGCCTGCGACGGATCACGAATATCCAGCAATCGGTGCGGCGCGGCGAGTAAC
TCTTCAGCATTCGGCTTCGCCGTCCCGATATCCATCCCTTTGTAAATAAGGGCAGAATCAACGCTTATCA
ACTCTACTGGTAAAATTTTACGCAGTTCAATGGCTAACGCCGTTTTACCGGAGGCCGTCGGCCCCATCAA
AAAAATCGCCTTAGGCAGGCTCGCCTTACTGATATCACTCA
Protein Sequence 
>gi|82779447|ref|YP_405796.1| tRNA delta(2)-isopentenylpyrophosphate transferase [Shigella dysenteriae Sd197] MSDISKASLPKAIFLMGPTASGKTALAIELRKILPVELISVDSALIYKGMDIGTAKPNAEELLAAPHRLLDIRDPSQAYSAADFRRDALAEMADITAAGRIPLLVGGTMLYFKALLEGLSPLPSADPEVRARIEQQAAEQGWESLHRQLQEVDPVAAARIHPNDPQRLSRALEVFFISGKTLTELTQTSGDALPYQVHQFAIAPASRELLHQRIEQRFHQMLASGFEAEVRALFARGDLHTDLPSIRCVGYRQMWSYLEGEISYDEMVYLGVCATRQLAKRQITWLRGWEGVHWLDSEKPEQARDEVLQVVGAIAG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: miaA mutants had reduced ability to invade and spread in MK2 cell monolayers compared to the wildtype (Durand et al., 1997).
COG COG0324J, under J: Translation, ribosomal structure and biogenesis
References
Durand et al., 1997: Durand JM, Björk GR, Kuwae A, Yoshikawa M, Sasakawa C. The modified nucleoside 2-methylthio-N6-isopentenyladenosine in tRNA of Shigella flexneri is required for expression of virulence genes. Journal of bacteriology. 1997; 179(18); 5777-5782. [PubMed: 9294434].