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vacB from Shigella dysenteriae Sd197

Victor ID 1533
Gene Name vacB from Shigella dysenteriae Sd197
Sequence Strain (Species/Organism) Shigella dysenteriae Sd197
NCBI Gene ID 3797372
NCBI Protein GI 161949985
Locus Tag SDY_4410
Protein Accession YP_405788.2
Other Database IDs UniProtKB-ID: Q328F8_SHIDS
UniRef100: UniRef100_Q328F8
UniRef90: UniRef90_P21499
UniRef50: UniRef50_P21499
UniParc: UPI00005E3919
EMBL: CP000034
EMBL-CDS: ABB64297.1
RefSeq_NT: NC_007606.1
EnsemblGenome: EBESCG00000082417.
EnsemblGenome_TRS: EBESCT00000083371
EnsemblGenome_PRO: EBESCP00000080351
GenomeReviews: CP000034_GR
KEGG: sdy:SDY_4410
NMPDR: fig|216598.1.peg.4836
eggNOG: COG0557
HOGENOM: HBG690243
OMA: TTERMTY
ProtClustDB: PRK11642
BioCyc: SDYS300267:SDY_4410-MONOMER
Taxonomy ID 300267
Gene Starting Position 4124743
Gene Ending Position 4127172
Gene Strand (Orientation) -
Protein Name exoribonuclease R
DNA Sequence 
>gi|82775382:4124743-4127172 Shigella dysenteriae Sd197, complete genome
ATCACTCTGCCACTTTTTTCTTCGCCGCACGCTTCGCTTTGGTCGCTGCAGCTATTTTCTGCGTTTTCGC
CGATGGCTTTTTCGCTTTTCTCGCGTCTTTTTTCGCTGCTTTCGGCTTCGTTTTTTTCTCACCGCGGAAG
GCGCTGTCTGGCTCAAAGTTAACCTTTTTACCGACCTGACGACGCTTGCCTGCATCGCCTTTTTTCGCTT
TCTCGCGCGCCGTTTTACCGACGTTGTGCGGTGCGCGTTCGCTGGAGATCAGGCTAAAGTCGATTTTGCG
CTCGTCCATATTAACCGCTTCGACGCGAACTTCCACGCGATCGCCCAGGCGATAAGTCTGGCCGCTGGAT
TCACCCATCAGTCGTTGCCCTACCTGGTCAAAGCGATAGTAGTCATTGTCCAGCGAAGAGACATGGACCA
GCCCATCAATGAACAAGTCGTCCAGACGGACGAAGAAGCCAAAGCCAGTGATGCTGGAAATTACGCCTTT
AAAGACGTTACCTACCTGGTCGAGCATGAAGTCACACTTCAGCCAGTCAGCCACATCGCGCGTTGCTTCG
TCGGCACGACGTTCCGCCATCGAACAGTGCTGACCCAGTTGCAGCATCTCTTCCATCGAATAATGATAGC
CGCCGGTTTCAGTGGTGTTGCCCTGATGCCCCTGCTCTTTCGCCAGCAGATACTTAATGGCGCGGTGCAG
CGTCAGGTCTGGATAACGACGAATCGGCGAAGTAAAGTGCGCATAGGACTGCAATGCCAGGCCAAAGTGA
CCACGGTTTTCCGGATCGTAAATCGCCTGTTTCATCGAGCGCAGCAGCATGGTTTGCAGCATTTCTGCAT
CAGGACGATCGGCAACCGACTCCAGTAGCTCCGCGTAGTCACGCGGTTCCGGCTTGTTACCGCCCGGCAG
TTCCAGCCCCAGCTCCGCCAGAACAGAACGGAAAGAGGTAATCGCTTCGGTGCTCGGCTTGTCGTGAATA
CGGAACAGTGCCGGTTCTTTCGCTTTCTCAACGAAACGCGCCGCCGAGATATTCGCCAGAATCATGCACT
CTTCAATTAACTTGTGTGCGTCGTTACGCTGAGTCTGTTCGATACGTTCAATACGGCGTTCAGCGTTGAA
AATGAACTTCGCTTCTTCGCTCTCAAATGAGATCCCGCCGCGTTCTTCACGGGCTTTATCCAGCACTTTA
TAGAGGTTATGCAACTCTTCGAGATGCTTAACCAGCGGGGCGTACTGCTCGCGCAGATCCTGATCGCCCT
GCAGAATATGCCAGACTTTGGTGTAGGTCAGACGCGCGTGAGAGCTCATCACCGCTTCGTAGAATTTGTA
GCCAGTCAGGCGGCCTTTCGACGAAACCGTCATCTCGCACACCATACACAGGCGGTCTACCTGCGGATTG
AGCGAGCACAGACCGTTAGAGAGCACTTCCGGCAGCATCGGGGTAACCTGCGAAGGGAAGTACACCGACG
TACCACGGTTACGCGCTTCTCTGTCCAGCGGCGTTGGCGGACGCACATAGTAGCTGACGTCAGCAATCGC
GACCCATAAACGCCAGCCGCCGCCGCGTTTTTTCTCGCAGTAAACTGCATCGTCAAAGTCACGGGCGTCT
TCGCCATCAATGGTGACCAGCGGTAAATCGCGCAGATCAACACGGCCCGCTTTTGCTTCTTCCGGCACTT
CTTCTTTCAGCCCGGTAACCTGTTGCTCAACAGCCTGCGGCCAGATGTACGGAATTTCATGGGTACGCAG
AGCGATATCAACCGCCATGCCGGTGCCCATATTATCGCCAAGGACTTCGACGATTTTACCCACCGCTTTG
GTGCGGCGAGTCGGACGCTGAGTCAGTTCGACTACGACCACAAAGCCCATCCGCGCGCCCATGATCTGAT
CGGGCGGGATTAAGATATCGAAGCTCAGACGGCTGTCGTCAGGAACCACAAAGCCGACGCCCGCTTCGGT
AAAGTAGCGACCAACAATCTGGCTGGTTTTTGGCACCAGTACGCGGACAATACGCGCTTCACGACGACCT
TTACGGTCAGCACCCAGCGGCTGAGCCAGCACCTGATCGCCATGAATGCAGGTTTTCATCTGCTCGCTGG
AGAGATACAAATCATCTTTACGCCCTTCAACCCGCAGAAAGCCGTAGCCATCACGGTGGCCAATAACGGT
ACCTTTCACCAGGTCGAGGCGTTCCGGCAGCGCATAGCACTGACGACGAGTGAAGACCAGTTGACCATCG
CGCTCCATCGCGCGCAGGCGGCGACGCAGGCCTTCAAGCTGCTCTTCGCCTTCAATGTGCAGTTCTACCG
CCAGCTCATCACGGCTGGCCGGTTTTTCACGTTTGGTTAAATGTTCGAGGATAAATTCCCGACTAGGGAT
GGGATTCGCGTATTTTTCAGCTTCGCGTTCCTGGAAAGGATCTTGTGACA
Protein Sequence 
>gi|161949985|ref|YP_405788.2| exoribonuclease R [Shigella dysenteriae Sd197] MSQDPFQEREAEKYANPIPSREFILEHLTKREKPASRDELAVELHIEGEEQLEGLRRRLRAMERDGQLVFTRRQCYALPERLDLVKGTVIGHRDGYGFLRVEGRKDDLYLSSEQMKTCIHGDQVLAQPLGADRKGRREARIVRVLVPKTSQIVGRYFTEAGVGFVVPDDSRLSFDILIPPDQIMGARMGFVVVVELTQRPTRRTKAVGKIVEVLGDNMGTGMAVDIALRTHEIPYIWPQAVEQQVTGLKEEVPEEAKAGRVDLRDLPLVTIDGEDARDFDDAVYCEKKRGGGWRLWVAIADVSYYVRPPTPLDREARNRGTSVYFPSQVTPMLPEVLSNGLCSLNPQVDRLCMVCEMTVSSKGRLTGYKFYEAVMSSHARLTYTKVWHILQGDQDLREQYAPLVKHLEELHNLYKVLDKAREERGGISFESEEAKFIFNAERRIERIEQTQRNDAHKLIEECMILANISAARFVEKAKEPALFRIHDKPSTEAITSFRSVLAELGLELPGGNKPEPRDYAELLESVADRPDAEMLQTMLLRSMKQAIYDPENRGHFGLALQSYAHFTSPIRRYPDLTLHRAIKYLLAKEQGHQGNTTETGGYHYSMEEMLQLGQHCSMAERRADEATRDVADWLKCDFMLDQVGNVFKGVISSITGFGFFVRLDDLFIDGLVHVSSLDNDYYRFDQVGQRLMGESSGQTYRLGDRVEVRVEAVNMDERKIDFSLISSERAPHNVGKTAREKAKKGDAGKRRQVGKKVNFEPDSAFRGEKKTKPKAAKKDARKAKKPSAKTQKIAAATKAKRAAKKKVAE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: vacB mutants had attenuated invasion of MK2 cells compared to the wild-type strain (Tobe et al., 1992).
COG COG0557K, under K: Transcription
References
Tobe et al., 1992: Tobe T, Sasakawa C, Okada N, Honma Y, Yoshikawa M. vacB, a novel chromosomal gene required for expression of virulence genes on the large plasmid of Shigella flexneri. Journal of bacteriology. 1992; 174(20); 6359-6367. [PubMed: 1400189].