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iroN

Victor ID 1532
Gene Name iroN
Sequence Strain (Species/Organism) Shigella dysenteriae Sd197
NCBI Gene ID 3797177
NCBI Protein GI 82776329
Locus Tag SDY_1022
Protein Accession YP_402678.1
Other Database IDs UniProtKB-ID: Q32HL8_SHIDS
UniRef100: UniRef100_Q32HL8
UniRef90: UniRef90_Q93K73
UniRef50: UniRef50_Q05098
UniParc: UPI00005E3147
EMBL: CP000034
EMBL-CDS: ABB61187.1
RefSeq_NT: NC_007606.1
EnsemblGenome: EBESCG00000081675.
EnsemblGenome_TRS: EBESCT00000082629
EnsemblGenome_PRO: EBESCP00000079609
GenomeReviews: CP000034_GR
KEGG: sdy:SDY_1022
NMPDR: fig|216598.1.peg.256
eggNOG: COG4771
HOGENOM: HBG464298
OMA: NDEHRLE
ProtClustDB: PRK13528
BioCyc: SDYS300267:SDY_1022-MONOMER
Taxonomy ID 300267
Gene Starting Position 963984
Gene Ending Position 966161
Gene Strand (Orientation) +
Protein Name TonB-dependent outer membrane siderophore receptor protein
DNA Sequence 
>gi|82775382:963984-966161 Shigella dysenteriae Sd197, complete genome
AATGAGAATTAACAAAATCCTCTGGTCGCTAACTGTGCTCCTGGTTGGGTTGAATAGCCAGATATCAGTA
GCCAAATACTCCGACGATGATAATGACGAGACTATGGTGGTGGAAGCCACCGCTGAGCAGGTATTAAAAC
AGCAGCCGGGCGTGTCGGTTATTACCAGCGAGGATATTAAAAAGACCCCTCCGGTAAACGACCTTTCAGA
TATTATTCGTAAAATGCCTGGTGTCAATCTTACCGGCAATAGCGCCTCGGGCACACGCGGTAATAACCGC
CAGATCGATATTCGTGGTATGGGGCCGGAAAACACCTTAATTTTAATTGATGGTGTACCGGTGACGTCAC
GTAACTCCGTGCGTTATAGCTGGCGTGGGGAGCGTGATACCCGCGGTGACACCAACTGGGTGCCACCGGA
ACAGGTTGAGCGTATTGAAGTGATCCGCGGCCCTGCGGCGGCGCGCTACGGTTCGGGGGCCGCCGGGGGG
GTGGTGAACATCATTACCAAACGTCCCACCAACGACTGGCACGGTTCGCTGTCGTTATACACCAACCAGC
CGGAAAGTAGCGAAGAGGGCGCTACGCGTCGCGCCAATTTCAGCCTTAGTGGGCCTCTGGCTGGTGATGC
TCTTACCACGCGTTTGTATGGTAACCTGAATAAAACGGATGCTGACAGTTGGGATATTAATTCTCCGGTC
GGTACGAAAAACGCAGCCGGGCATGAAGGGGTACGTAACAAAGATATTAACGGCGTTATCTCGTGGAAAT
TAAATCCGCAGCAGATTCTCGATTTCGAAGCCGGATATAGCCGCCAGGGGAATATCTATGCGGGCGATAC
GCAGAACAGTTCTTCCAGTGCAGTTACCGAAAGCCTGGCAAAATCCGGCAAAGAGACGAACCGCCTGTAC
CGACAGAATTATGGCATTACGCATAATGGTATCTGGGACTGGGGACAAAGTCGCTTTGGTGTTTATTACG
AGAAAACCAATAATACCCGCATGAATGAAGGATTATCCGGCGGTGGTGAAGGACGTATTTTAGCGGGTGA
AAAGTTTACGACCAATCGCCTGAGTTCCTGGCGAACCAGCGGTGAGCTTAATATTCCTTTGAATGTGATG
GTTGATCAAACGCTGACCGTTGGTGCAGAGTGGAACCGCGATAAGCTCGATGATCCTTCCTCTACCAGCC
TGACGGTGAATGACAGAGATATCAGCGGTATTTCTGGCTCTGCTGCGGATCGCAGCAGTAAAAATCATTC
TCAAATCAGTGCGCTGTATATTGAAGATAACATTGAGCCGGTTCCTGGCACGAATATCATTCCCGGCCTG
CGCTTTGATTATCTCAGCGACTCCGGCGGGAACTTCAGCCCCAGTCTGAATCTTTCGCAGGAATTGGGCG
ATTATTTCAAAGTCAAAGCAGGGGTTGCCCGAACCTTTAAAGCCCCAAACCTGTATCAATCCAGTGAAGG
CTATCTGCTCTACTCGAAAGGCAATGGCTGTCCAAAAGATATTACATCAGGCGGGTGCTACCTGATCGGT
AATAAAGATCTCGATCCGGAAATCAGTGTCAATAAAGAAATTGGACTGGAGTTCACCTGGGAAGATTACC
ACGCAAGTGTGACCTACTTCCGCAATGATTACCAGAATAAGATCGTGGCCGGGGATAACGTTATAGGGCA
AACCGCTTCAGGCGCATATATCCTCAAGTGGCAGAATGGCGGGAAAGCTCTGGTGGACGGTATCGAAGCC
AGTATGTCTTTACCACTGGTGAAAGATCGTCTGAACTGGAATACCAATGCCACATGGATGATCACTTCGG
AGCAAAAAGACACCGGTAATCCTCTGTCGGTCATCCCGAAATATACTATCAATAACTCGCTTAACTGGAC
CATCACCCAGGCGTTTTCTGCCAGCGTCAACTGGACGTTATATGGCAGACAAAAACCGCGTACTCATGCG
GAAACCCGCAGTGAAGATACTGGCGGTCTGTCAGGTAAAGAGCTGGGCGCTTATTCACTGGTGGGGACGA
ACTTCAATTACGATATTAATAAAAATCTGCGTCTTAATGTCGGCGTCAGTAATATCCTCAATAAACAGAT
CTTCCGATCTTCTGAAGGGGCGAATACCTATAACGAGCCAGGCCGGGCTTACTATGCCGGAGTTACCGCA
TCATTCTG
Protein Sequence 
>gi|82776329|ref|YP_402678.1| outer membrane receptor FepA [Shigella dysenteriae Sd197] MRINKILWSLTVLLVGLNSQISVAKYSDDDNDETMVVEATAEQVLKQQPGVSVITSEDIKKTPPVNDLSDIIRKMPGVNLTGNSASGTRGNNRQIDIRGMGPENTLILIDGVPVTSRNSVRYSWRGERDTRGDTNWVPPEQVERIEVIRGPAAARYGSGAAGGVVNIITKRPTNDWHGSLSLYTNQPESSEEGATRRANFSLSGPLAGDALTTRLYGNLNKTDADSWDINSPVGTKNAAGHEGVRNKDINGVISWKLNPQQILDFEAGYSRQGNIYAGDTQNSSSSAVTESLAKSGKETNRLYRQNYGITHNGIWDWGQSRFGVYYEKTNNTRMNEGLSGGGEGRILAGEKFTTNRLSSWRTSGELNIPLNVMVDQTLTVGAEWNRDKLDDPSSTSLTVNDRDISGISGSAADRSSKNHSQISALYIEDNIEPVPGTNIIPGLRFDYLSDSGGNFSPSLNLSQELGDYFKVKAGVARTFKAPNLYQSSEGYLLYSKGNGCPKDITSGGCYLIGNKDLDPEISVNKEIGLEFTWEDYHASVTYFRNDYQNKIVAGDNVIGQTASGAYILKWQNGGKALVDGIEASMSLPLVKDRLNWNTNATWMITSEQKDTGNPLSVIPKYTINNSLNWTITQAFSASVNWTLYGRQKPRTHAETRSEDTGGLSGKELGAYSLVGTNFNYDINKNLRLNVGVSNILNKQIFRSSEGANTYNEPGRAYYAGVTASF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: iroN mutant was attenuated in HeLa cells subjected to an iron chelator, DIP to produce iron deficient conditions, suggesting that iroN plays a role in virulence in iron deficient conditions (Bin et al., 2006).
COG COG4771P, under P: Inorganic ion transport and metabolism
References
Bin et al., 2006: Bin W, Liu M, Peng J, Sun L, Xu X, Zhang J, Jin Q. Construction, detection and microarray analysis on Shigella dysenteriae a1 IroN, ShuA single, double mutants. Science in China. Series C, Life sciences / Chinese Academy of Sciences. 2006; 49(3); 251-258. [PubMed: 16856494].