Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

virK from Shigella dysenteriae Sd197

Victor ID 1517
Gene Name virK from Shigella dysenteriae Sd197
Sequence Strain (Species/Organism) Shigella dysenteriae Sd197
NCBI Gene ID 3776611
NCBI Protein GI 82524515
Locus Tag SDY_P109
Protein Accession YP_406110.1
Other Database IDs UniProtKB-ID: Q326Y6_SHIDS
UniRef100: UniRef100_Q326Y6
UniRef90: UniRef90_Q08JR6
UniRef50: UniRef50_Q9X694
UniParc: UPI00000AFB9B
EMBL: CP000035
EMBL-CDS: ABB64622.1
RefSeq_NT: NC_007607.1
EnsemblGenome: EBESCG00000083929.
EnsemblGenome_TRS: EBESCT00000084883
EnsemblGenome_PRO: EBESCP00000081707
GenomeReviews: CP000035_GR
KEGG: sdy:SDY_P109
eggNOG: COG2990
HOGENOM: HBG468105
OMA: FHASYDE
ProtClustDB: CLSK862866
BioCyc: SDYS300267:SDY_P109-MONOMER
Taxonomy ID 300267
Plasmid No pSD1_197
Gene Starting Position 88029
Gene Ending Position 88979
Gene Strand (Orientation) +
Protein Name required for proper localization of IcsA (VirG) at the surface of bacteria
DNA Sequence 
>gi|82524407:88029-88979 Shigella dysenteriae Sd197 plasmid pSD1_197, complete sequence
TATGTTTTCTGTAAGTAACTTATCATTTATCGGTTTCCTTAAAAGGATTGTTTTTTCCTCAGATTCACTC
CCGGGGAAGTGGGAACACAGAAAATTCCGGTTCATGTACATTTTGCGATGTGCTATAAATCCGGTTGCCA
GTATTCGATATTATTACGAACTGCGTTCCTTGCAGTGCATTGAGGATATTCTGGCAATACAACCCACGTT
GCCAGCAAGAATTCATCGACCTTATTTGCATAAAGGGGGGCGAGCCTGGTCACGGGGGCAATATATTCTT
GAGCATTATCGCTTTGTGCAAAATTTGCCAGAAAAATATTCTGAATTTTTGTTTCCACAAAAATCGGTAT
CATTAGTCCAATTCATCGGGAAAGATGGAGAGGATTTTGATATCCAGTGTTCTCCCAGTGGTTTTGACCG
GGAAGGAGAGTTGATGTTGTCATTGTTTTTCAATAAAATAGTGATTGCCCGGTTAACATTTTCAGTCATT
CTGACTCAAAATGGACACACCGCTTTTATTGGCGGATTACAGGGAGCCCCCAAAAATACCGGACCTGATG
TTATTCGGTGCGCAACCCGGGCCTGTTATGGGCTTTTCCCAAAACGGATTATTTTTGAAGCATTTTGTGC
GTTGATGAAAGCTTGTAATGTCTCTGAGTGTCTGGCAGTCAGTGAGCACAGTCATGTTTTCCGGCAATTG
AGATACTGGTATCAGAAACGCAAAACCTTTGTTGCTGTATACAGTGATTTCTGGGAGTCTGTAGCAGGGA
AAACCTGTGGTGACTGGTACAAATTACCAACACAGGTGGTTCGAAAGCCGCTAAGCAATATAGCTAGTAA
AAAACGCTCTGAGTATCGAAAACGATACGCTTTGTTGGATTATATCCATGAAACTGCTATCCGCTCTTTG
GATGCATATCCTGTAAACTCAGAACATCAGGACTTAAATTA
Protein Sequence 
>gi|82524515|ref|YP_406110.1| VirK [Shigella dysenteriae Sd197] MFSVSNLSFIGFLKRIVFSSDSLPGKWEHRKFRFMYILRCAINPVASIRYYYELRSLQCIEDILAIQPTLPARIHRPYLHKGGRAWSRGQYILEHYRFVQNLPEKYSEFLFPQKSVSLVQFIGKDGEDFDIQCSPSGFDREGELMLSLFFNKIVIARLTFSVILTQNGHTAFIGGLQGAPKNTGPDVIRCATRACYGLFPKRIIFEAFCALMKACNVSECLAVSEHSHVFRQLRYWYQKRKTFVAVYSDFWESVAGKTCGDWYKLPTQVVRKPLSNIASKKRSEYRKRYALLDYIHETAIRSLDAYPVNSEHQDLN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: virK mutants have attenuated ability for intracellular spreading in host cells (Wing et al., 2005).
COG COG2990S, under S: Function unknown
References
Wing et al., 2005: Wing HJ, Goldman SR, Ally S, Goldberg MB. Modulation of an outer membrane protease contributes to the virulence defect of Shigella flexneri strains carrying a mutation in the virK locus. Infection and immunity. 2005; 73(2); 1217-1220. [PubMed: 15664968].