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virB from Shigella dysenteriae Sd197

Victor ID 1508
Gene Name virB from Shigella dysenteriae Sd197
Sequence Strain (Species/Organism) Shigella dysenteriae Sd197
NCBI Gene ID 3776565
NCBI Protein GI 82524567
Locus Tag SDY_P161
Protein Accession YP_406162.1
Other Database IDs UniProtKB-ID: Q326T4_SHIDS
UniRef100: UniRef100_P0A247
UniRef90: UniRef90_P0A247
UniRef50: UniRef50_P0A247
UniParc: UPI0000000B47
EMBL: CP000035
EMBL-CDS: ABB64674.1
RefSeq_NT: NC_007607.1
EnsemblGenome: EBESCG00000084020.
EnsemblGenome_TRS: EBESCT00000084974
EnsemblGenome_PRO: EBESCP00000081798
GenomeReviews: CP000035_GR
KEGG: sdy:SDY_P161
eggNOG: COG1475
HOGENOM: HBG679439
OMA: EVNGRIE
ProtClustDB: CLSK862821
BioCyc: SDYS300267:SDY_P161-MONOMER
Taxonomy ID 300267
Plasmid No pSD1_197
Gene Starting Position 127893
Gene Ending Position 128822
Gene Strand (Orientation) -
Protein Name transcriptional activator required for tanscription of the ipa, mxi, and spa operons
DNA Sequence 
>gi|82524407:127893-128822 Shigella dysenteriae Sd197 plasmid pSD1_197, complete sequence
TTTATGAAGACGATAGATGGCGAGAAATTATATCCCGAATAGCTTCATCTATTTCTCTCTGAACTGTTTT
GTTTATTTTAGATAATGTAAATATTAGAGTTCTGTTTGTTTTATTCTCTTTTCTTTTTATGTAAGTCCGT
TTGTCTTTAGAAATAAATAACGAGTCAACTTTTAGCGAAGGGTTTTGCTTTCTGTTTTTGCTTTTCTTTA
TGATGTTTAAAATTTCTTTTTTATATATGTCCGGGGGCAAATTTGTATCAAGGTCTTTTATTTCTTCCTT
TAATATTGGTAGTGTAGAACTAAGAGATTCATTAGCCTTTTCAAGTCCTTTATAATAATTGAATAATATC
TTGTAGTCATTAAAGTTAAGTTCTGACGCGATTGGAAATAGAGATATTATTTCCTGTGGAACGCTTGCTG
CCTGAAAGGCACGAGTGACTTTCGCGCGAGACAGATTCTCTTTTTTGGCTATGTCTTTATAGGACATCCC
TGATACTTTCAGAAAATTAAGACCAATACCAAGTTCTCGGATGCTATGCTCTTTTGCTGTTTGTATATCG
TTTGCTAGTTTTCTGGCATCAAGAGTAGATATATATTCTTTTGAATATAGAACTTCAAGATCTGCTCCTG
CATATATTGCAGATGCTCTTCTACGAGTGCCATCCAGAATTTCAATTCTACCATCAATCTCCCTTCCTAT
TACAGGGAAGAATTGTTGCAGCTTTATAGTTTTTATGATATCGGCTAATGATTCTTCTGTTAGGGATTCT
TGATCGCGTACATTCGTTTTTTGGTTGACGAAGGTTAAATCTTGGATCCTTTTATGAGGAATCTTGGCTT
TGATAAAGGAAACTTTATTACCAGAATGGAGTGTAAACTCTTTCTTTTGGCCTTCCTTTATACTTAACAA
GTCGTTGCACAAATCCACCA
Protein Sequence 
>gi|82524567|ref|YP_406162.1| VirB [Shigella dysenteriae Sd197] MVDLCNDLLSIKEGQKKEFTLHSGNKVSFIKAKIPHKRIQDLTFVNQKTNVRDQESLTEESLADIIKTIKLQQFFPVIGREIDGRIEILDGTRRRASAIYAGADLEVLYSKEYISTLDARKLANDIQTAKEHSIRELGIGLNFLKVSGMSYKDIAKKENLSRAKVTRAFQAASVPQEIISLFPIASELNFNDYKILFNYYKGLEKANESLSSTLPILKEEIKDLDTNLPPDIYKKEILNIIKKSKNRKQNPSLKVDSLFISKDKRTYIKRKENKTNRTLIFTLSKINKTVQREIDEAIRDIISRHLSSS
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: virB mutants have an avirulent phenotype and do not invade host cells (Sasakawa et al., 1993).
COG COG1475K, under K: Transcription
References
Sasakawa et al., 1993: Sasakawa C, Komatsu K, Tobe T, Suzuki T, Yoshikawa M. Eight genes in region 5 that form an operon are essential for invasion of epithelial cells by Shigella flexneri 2a. Journal of bacteriology. 1993; 175(8); 2334-2346. [PubMed: 8385666].