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mxiK from Shigella dysenteriae Sd197

Victor ID 1498
Gene Name mxiK from Shigella dysenteriae Sd197
Sequence Strain (Species/Organism) Shigella dysenteriae Sd197
NCBI Gene ID 3776534
NCBI Protein GI 82524584
Locus Tag SDY_P178
Protein Accession YP_406179.1
Other Database IDs UniProtKB-ID: Q326R7_SHIDS
UniRef100: UniRef100_Q326R7
UniRef90: UniRef90_P0A227
UniRef50: UniRef50_P0A227
UniParc: UPI00005E3A14
EMBL: CP000035
EMBL-CDS: ABB64691.1
RefSeq_NT: NC_007607.1
EnsemblGenome: EBESCG00000083979.
EnsemblGenome_TRS: EBESCT00000084933
EnsemblGenome_PRO: EBESCP00000081757
GenomeReviews: CP000035_GR
KEGG: sdy:SDY_P178
HOGENOM: HBG210273
OMA: VGVYERI
ProtClustDB: CLSK505052
BioCyc: SDYS300267:SDY_P178-MONOMER
Taxonomy ID 300267
Plasmid No pSD1_197
Gene Starting Position 143326
Gene Ending Position 143844
Gene Strand (Orientation) +
Protein Name putative component of the Mxi-Spa secretion machinery
DNA Sequence 
>gi|82524407:143326-143844 Shigella dysenteriae Sd197 plasmid pSD1_197, complete sequence
AATGGATGGAATTTATAAAAAATATCTTTCAATAATTTTTGATCCAGCGTTCTATATAAATAGAAATCGG
TTAAATTTGCCTTCTGAACTGTTAGAAAATGGCGTAATCAGAAGTGAGATTAATAATCTCATAATTAATA
AATATGATCTAAATTGCGATATTGATCCTTTAAGCGGGGTAACCGCTATGTTTGTTGCCAACTGGAATTT
ACTTCCAGCTGTTGCTTATTTTATCGGTAGTCAAGAGTCTCGGTTAATTAATCATAGTGAGATGGTTATT
AGTTATTATGGGGGCAAAATCAGTAAGCAAGGGGAGGCCGCTATTCGAAGTGGTTTTTGGCATCTTATTG
CGTGGAAGGAAAATATATCTGTTGGTGTATATGAAAGAATAAACTTATTATTTAATCCAATTGTTTTGGA
GGGAAATTATACGCCTGTAGAAAGAAATTTGTCCCGATTAAATGAAGGTATGCAATATGCAAAAAGGCAC
TTTACCGGTATCCAGACATCATGCCTATG
Protein Sequence 
>gi|82524584|ref|YP_406179.1| MxiK [Shigella dysenteriae Sd197] MDGIYKKYLSIIFDPAFYINRNRLNLPSELLENGVIRSEINNLIINKYDLNCDIDPLSGVTAMFVANWNLLPAVAYFIGSQESRLINHSEMVISYYGGKISKQGEAAIRSGFWHLIAWKENISVGVYERINLLFNPIVLEGNYTPVERNLSRLNEGMQYAKRHFTGIQTSCL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: mxiK mutants are unable to invade HeLa cells (Jouihri et al., 2003).
References
Jouihri et al., 2003: Jouihri N, Sory MP, Page AL, Gounon P, Parsot C, Allaoui A. MxiK and MxiN interact with the Spa47 ATPase and are required for transit of the needle components MxiH and MxiI, but not of Ipa proteins, through the type III secretion apparatus of Shigella flexneri. Molecular microbiology. 2003; 49(3); 755-767. [PubMed: 12864857].