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mxiJ from Shigella dysenteriae Sd197

Victor ID 1497
Gene Name mxiJ from Shigella dysenteriae Sd197
Sequence Strain (Species/Organism) Shigella dysenteriae Sd197
NCBI Gene ID 3776533
NCBI Protein GI 82524583
Locus Tag SDY_P177
Protein Accession YP_406178.1
Other Database IDs UniProtKB-ID: Q326R8_SHIDS
UniRef100: UniRef100_Q326R8
UniRef90: UniRef90_Q06081
UniRef50: UniRef50_Q06081
UniParc: UPI00005E3A13
EMBL: CP000035
EMBL-CDS: ABB64690.1
RefSeq_NT: NC_007607.1
EnsemblGenome: EBESCG00000084081.
EnsemblGenome_TRS: EBESCT00000085035
EnsemblGenome_PRO: EBESCP00000081859
GenomeReviews: CP000035_GR
KEGG: sdy:SDY_P177
NMPDR: fig|216598.1.peg.2911
eggNOG: COG4669
HOGENOM: HBG671305
OMA: HISVIAI
ProtClustDB: CLSK2392807
BioCyc: SDYS300267:SDY_P177-MONOMER
Taxonomy ID 300267
Plasmid No pSD1_197
Gene Starting Position 142595
Gene Ending Position 143320
Gene Strand (Orientation) +
Protein Name lipoprotein, component of the Mxi-Spa secretion machinery
DNA Sequence 
>gi|82524407:142595-143320 Shigella dysenteriae Sd197 plasmid pSD1_197, complete sequence
TATGATTAGGTATAAATTTTTTATTTTATTCTTGTTGCTGATGCTGATTGGATGTGAGCAACGTGACGAG
TTAATTTCCAATTTGTCTCAAAGACAGGCAAATGAAATAATATCTGTGCTAGAACGCCATAATATTTCTG
CTAGAAAAGTTGATGGAGGTAAACAGGGAATCTCAGTACAAGTCGAAAAGGGGACATTTGCATCGGCAGT
TGATTTGATGCGCATGTACGATTTGCCAAATCCGGAGAGAGTTGATATCTCACAAATGTTTCCTACAGAT
TCGTTAGTATCTTCTCCAAGAGCTGAAAAGGCCCGTTTATATAGTGCTATTGAGCAACGGCTGGAGCAGT
CTTTAGTTTCTATTGGTGGTGTTATTTCGGCAAAAATACATGTTAGCTATGATCTTGACGATAAGAATAT
ATCTTCAAAACCGATGCATATATCAGTAATTGCTATATATGACTCACCGAAAGAGTCTGAACTATTAGTT
AGTAATATTAAGCGATTTTTGAAAAATACTTTTTCTGATGTTAAGTATGAAAATATATCTGTCATATTAA
CTCCGAAAGAAGAATATGTTTATACAAATGTACAACCTGTTAAGGAAACTAAATCGGAATTTTTAATAAA
TGAAGTAATATATGTATTTCTCGGGATGGCTGTACTGGTCGTCATTCTTTTGGTATGGGCATTCAAAACA
GGGTGGTTCAAGAGAAACAAAATATG
Protein Sequence 
>gi|82524583|ref|YP_406178.1| MxiJ [Shigella dysenteriae Sd197] MIRYKFFILFLLLMLIGCEQRDELISNLSQRQANEIISVLERHNISARKVDGGKQGISVQVEKGTFASAVDLMRMYDLPNPERVDISQMFPTDSLVSSPRAEKARLYSAIEQRLEQSLVSIGGVISAKIHVSYDLDDKNISSKPMHISVIAIYDSPKESELLVSNIKRFLKNTFSDVKYENISVILTPKEEYVYTNVQPVKETKSEFLINEVIYVFLGMAVLVVILLVWAFKTGWFKRNKI
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: mxiJ mutant was unable to invade HeLa cells, to induce the formation of plaques on confluent monolayers of HeLa cells, and to provoke keratoconjunctivitis in guinea pigs (Allaoui et al., 1992).
COG COG4669U, under U: Intracellular trafficking, secretion, and vesicular transport
References
Allaoui et al., 1992: Allaoui A, Sansonetti PJ, Parsot C. MxiJ, a lipoprotein involved in secretion of Shigella Ipa invasins, is homologous to YscJ, a secretion factor of the Yersinia Yop proteins. Journal of bacteriology. 1992; 174(23); 7661-7669. [PubMed: 1332940].