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icsB from Shigella dysenteriae Sd197

Victor ID 1492
Gene Name icsB from Shigella dysenteriae Sd197
Sequence Strain (Species/Organism) Shigella dysenteriae Sd197
NCBI Gene ID 3776526
NCBI Protein GI 82524576
Locus Tag SDY_P170
Protein Accession YP_406171.1
Other Database IDs UniProtKB-ID: Q326S5_SHIDS
UniRef100: UniRef100_Q326S5
UniRef90: UniRef90_P33546
UniRef50: UniRef50_P33546
UniParc: UPI00005E3A0E
EMBL: CP000035
EMBL-CDS: ABB64683.1
RefSeq_NT: NC_007607.1
EnsemblGenome: EBESCG00000083940.
EnsemblGenome_TRS: EBESCT00000084894
EnsemblGenome_PRO: EBESCP00000081718
GenomeReviews: CP000035_GR
KEGG: sdy:SDY_P170
NMPDR: fig|216598.1.peg.2914
eggNOG: NOG147445
HOGENOM: HBG683611
OMA: KSENCAG
ProtClustDB: CLSK688131
BioCyc: SDYS300267:SDY_P170-MONOMER
Taxonomy ID 300267
Plasmid No pSD1_197
Gene Starting Position 136656
Gene Ending Position 138140
Gene Strand (Orientation) -
Protein Name invasion protein
DNA Sequence 
>gi|82524407:136656-138140 Shigella dysenteriae Sd197 plasmid pSD1_197, complete sequence
TCTATATATTAGAATGAGAGTTATTCAATAAAAGCTTATTGACCTGTAATAAGTCGTGAATGTAAAGTTT
GGTTCCAAGATCTGGCGATTTAAGAGAATTGTAATAATCAATAGTTTTTATTGACTTTTCGATAATTTCT
TCTTTTTTATCTGTTGCTCCGGTTTTTAATTCGTTTAATACACGAGACATATTGCTGGGTGCTGATTTTA
CTAAGTATGAGTGGCAAGCGTTGATGACCGCATCAAAGTCTTCTGAAGATACATTTTCAGTAGGATGTTT
GTAAAGTGAAATTGATAAAGGCTTGAATGTTTTTGGGGTGTGGATAAGGTTAATTTTATTGAAACTTTTA
AGATAGCTACGTCGTAATTGAGTCAATCTGGAAAGATCAAAATCAGATTCAATATACTTCATTATCTCGT
TATAAGACTGATTGAGACTTTCAATGCGTTGCCTAACTTTATTTGCATACGCGTATACATTGTTAGGTGT
AGCAACCAATTTAACGTCAGGGAGTGGAAAGTATATTTCAGAATTTCCTGCTTTAAGAACATTAAGTGCC
ATACCAGCACAGTTTTCAGATTTACTGATTAATTTATAATTTGCCAATTGTCTGAAAGCATCTGCTTTCT
TTTGGCATATAAATTTTGACATGTTTGTTTCATCAAGGCCAAAAAGGTTATAGCTGATTTTACCATCCTT
TGTTTTATTATCACCTGATAATGGAATGTATACTTTATCAGCACTGACCCCCCAATAACCATAGGGATCT
TTTTTTTGATTAGCTCTGGGAAAAAATATTTTTTTGTTGTTATTTTGATCTTGTTTTGAATTTAATAAGT
TTCTAACCTCTTGGCCTGCATCAAGTCTTTCGGCTGTTTGGTCTGAAATCATATTTAGTTTGTCTTGTTT
ATAGGTATCGACACTGTAACCTGAGCGTTTTTCAAAAAGGTAGTTTATTTCTGTATCTTTTGTAACATTC
CCGCCGGGATACCAGCTGAGATAGGTATGAGTTGGTTCCTGTAGTAAATTGTTTTTTATACTGATACTGG
TATGCCCTAAATGGGTTATGCCTCTATTTTCCCAGCAACGAAAAACTAAATGTCTTTCAAGATTTTTGGC
TGTACCGATGCCATGAAAACGCTCTGCGGTATTCAACATTAATTTGATGTCTTTACCTGTAAAAGAATGT
TGAATTGAATTTTTGACTGCTTCATAGGCGGCAAACGCACTTTCTGCAGATTTTTCGCTAGCTAATGTCT
TGAGAAAAAGCAATAAGGATTTTTGATTCGCTAGTCGATAATTTTTTAGTTGTTCATTTAATATCTGTGA
ATTTATCTTTGCATTAATAGTGCTTAATGTTCTGAAAAAGAGATCCTTTAGGTTGAATTTTTGTGCTACC
AATATAGGTCCATGCTCTGTATCTTCAACGCGTATGGGCCCTTTTGTATTGCTTGCGTCAATGAAATTGC
TAATTTTGAGAATCA
Protein Sequence 
>gi|82524576|ref|YP_406171.1| IcsB [Shigella dysenteriae Sd197] MILKISNFIDASNTKGPIRVEDTEHGPILVAQKFNLKDLFFRTLSTINAKINSQILNEQLKNYRLANQKSLLLFLKTLASEKSAESAFAAYEAVKNSIQHSFTGKDIKLMLNTAERFHGIGTAKNLERHLVFRCWENRGITHLGHTSISIKNNLLQEPTHTYLSWYPGGNVTKDTEINYLFEKRSGYSVDTYKQDKLNMISDQTAERLDAGQEVRNLLNSKQDQNNNKKIFFPRANQKKDPYGYWGVSADKVYIPLSGDNKTKDGKISYNLFGLDETNMSKFICQKKADAFRQLANYKLISKSENCAGMALNVLKAGNSEIYFPLPDVKLVATPNNVYAYANKVRQRIESLNQSYNEIMKYIESDFDLSRLTQLRRSYLKSFNKINLIHTPKTFKPLSISLYKHPTENVSSEDFDAVINACHSYLVKSAPSNMSRVLNELKTGATDKKEEIIEKSIKTIDYYNSLKSPDLGTKLYIHDLLQVNKLLLNNSHSNI
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: icsB mutants are attenuated in guinea pig eyes (Ogawa et al., 2003).
References
Ogawa et al., 2003: Ogawa M, Suzuki T, Tatsuno I, Abe H, Sasakawa C. IcsB, secreted via the type III secretion system, is chaperoned by IpgA and required at the post-invasion stage of Shigella pathogenicity. Molecular microbiology. 2003; 48(4); 913-931. [PubMed: 12753186].