Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

spa32 from Shigella dysenteriae Sd197

Victor ID 1489
Gene Name spa32 from Shigella dysenteriae Sd197
Sequence Strain (Species/Organism) Shigella dysenteriae Sd197
NCBI Gene ID 3776506
NCBI Protein GI 82524595
Locus Tag SDY_P189
Protein Accession YP_406190.1
Other Database IDs UniProtKB-ID: Q326Q6_SHIDS
UniRef100: UniRef100_Q326Q6
UniRef90: UniRef90_P0A1K5
UniRef50: UniRef50_P0A1K5
UniParc: UPI00005E3A1F
EMBL: CP000035
EMBL-CDS: ABB64702.1
RefSeq_NT: NC_007607.1
EnsemblGenome: EBESCG00000083875.
EnsemblGenome_TRS: EBESCT00000084829
EnsemblGenome_PRO: EBESCP00000081653
GenomeReviews: CP000035_GR
KEGG: sdy:SDY_P189
NMPDR: fig|216598.1.peg.2905
HOGENOM: HBG210275
OMA: HTSSANP
ProtClustDB: CLSK505062
BioCyc: SDYS300267:SDY_P189-MONOMER
Taxonomy ID 300267
Plasmid No pSD1_197
Gene Starting Position 153029
Gene Ending Position 153907
Gene Strand (Orientation) +
Protein Name secreted by and component of the Mxi-Spa machinery
DNA Sequence 
>gi|82524407:153029-153907 Shigella dysenteriae Sd197 plasmid pSD1_197, complete sequence
CATGGCATTAGATAATATAAACTTAAATTTTAGTAGTGACAAACAGATAGAAAAATGTGAGAAACTATCT
TCAATAGATAATATTGATAGTCTTGTTTTGAAGAAGAAGAGGAAGGTTGAAATTCCTGAGTACTCTTTAA
TTGCATCTAACTATTTTACTATTGATAAGCACTTTGAACATAAGCATGATAAAGGAGAAATTTATAGTGG
CATTAAAAATGCGTTCGAACTTAGAAACGAACGAGCGACATATTCTGATATTCTAGAATCAATGGTCATT
AAAGAAAATATTTTGATACCAGTTCAAGATATCAAAGCAAGGGAAAAAATAAATATCGGCGATATGAGGG
GGATCTTTTCATATAATGAGAGTGGAAATGCAGACAAGAACTTCGAAAGAAGTCATACTTCTTCTGCAAA
CCCTGATAATCTGCTAGAACCTGATAATAGAAATAGTCAAATTGGTTTAAAAAATCATAGCTTATCTATT
GATAAGAATATTGCTGACATTATTTCTTTGCTAAATGGAAGTGTTGCTAAGTCATTTGATCTGCCTGTAA
TGAAAAAAAATACTTCAGACATAACCCCATCCATGTCATTGCAAGAAAAATCAATAGTTGAAAATGATAA
AAATGTTTATCAAAAAAATAGTGAAATGACTTACCACTTTAAACAGTGGGGGGCTGGACATTCTGTTAGT
ATTTCAGTGGAGTCTGGTTCTTTTGTTCTAAAACCGTCAGATCAGTTTGTAGGAAATAAACTTGACTTAA
TTTTGAAACAAGATGCTGAGGGTAATTACAGATTTGATAGCAGTCAACATAATAAGGGGAATAAAAATAA
TAGTACAGGATATAATGAACAGAGTGAAGAAGAATGCTA
Protein Sequence 
>gi|82524595|ref|YP_406190.1| Spa32 [Shigella dysenteriae Sd197] MALDNINLNFSSDKQIEKCEKLSSIDNIDSLVLKKKRKVEIPEYSLIASNYFTIDKHFEHKHDKGEIYSGIKNAFELRNERATYSDILESMVIKENILIPVQDIKAREKINIGDMRGIFSYNESGNADKNFERSHTSSANPDNLLEPDNRNSQIGLKNHSLSIDKNIADIISLLNGSVAKSFDLPVMKKNTSDITPSMSLQEKSIVENDKNVYQKNSEMTYHFKQWGAGHSVSISVESGSFVLKPSDQFVGNKLDLILKQDAEGNYRFDSSQHNKGNKNNSTGYNEQSEEEC
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: spa32 mutants are unable to invade HeLa cells and do not secrete type III effectors (Tamano et al., 2002).
References
Tamano et al., 2002: Tamano K, Katayama E, Toyotome T, Sasakawa C. Shigella Spa32 is an essential secretory protein for functional type III secretion machinery and uniformity of its needle length. Journal of bacteriology. 2002; 184(5); 1244-1252. [PubMed: 11844752].