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ipgB2 from Shigella dysenteriae Sd197

Victor ID 1485
Gene Name ipgB2 from Shigella dysenteriae Sd197
Sequence Strain (Species/Organism) Shigella dysenteriae Sd197
NCBI Gene ID 3776481
NCBI Protein GI 82524431
Locus Tag SDY_P025
Protein Accession YP_406026.1
Other Database IDs UniProtKB-ID: Q327H0_SHIDS
UniRef100: UniRef100_Q327H0
UniRef90: UniRef90_Q327H0
UniRef50: UniRef50_Q327H0
UniParc: UPI00005E39A3
EMBL: CP000035
EMBL-CDS: ABB64538.1
RefSeq_NT: NC_007607.1
EnsemblGenome: EBESCG00000084059.
EnsemblGenome_TRS: EBESCT00000085013
EnsemblGenome_PRO: EBESCP00000081837
GenomeReviews: CP000035_GR
KEGG: sdy:SDY_P025
NMPDR: fig|216598.1.peg.2881
HOGENOM: HBG683966
OMA: RISLDIN
ProtClustDB: CLSK540077
BioCyc: SDYS300267:SDY_P025-MONOMER
Taxonomy ID 300267
Plasmid No pSD1_197
Gene Starting Position 20652
Gene Ending Position 21227
Gene Strand (Orientation) +
Protein Name probably secreted by the Mxi-Spa secretion machinery
DNA Sequence 
>gi|82524407:20652-21227 Shigella dysenteriae Sd197 plasmid pSD1_197, complete sequence
AGTGATTATAATGCTTGGAACATCTTTTAATAATTTTGGAATCAGTTTATCTCACAAAAGATATTTTTCA
GGAAAGGTGGATGAGATTATCCGCTGTACAATGGGGAAAAGGATAGTAAAAATATCATCAACCAAAATAA
ATACTAGTATTTTGAGCTCTGTTTCAGAACAAATCGGTGAAAATATTACAGATTGGAAAAATGATGAAAA
AAAAGTCTACGTATCCCGGGTGGTAAACCAATGTATTGATAAGTTTTGTGCAGAACACAGCCGAGAAATC
GGCGATAACCTCCGTAAACAGATATTTAAACAGGTTGAGAAAGATTATCGCATTTCTCTAGACATCAATG
CTGCACAAAGTTCCATAAATCATCTTGTATCAGGAAGCAGTTATTTCAAAAAGAAAATGGACGAACTTTG
TGAAGGGATGAATAGAAGCGTTAAAAATGATACAACAAGCAATGTTGTAAATCTTATTTCCGATCAGTTT
TTTGAGAAAAATGTGCAATATATTGATCTAAAGAAACTACGTGGGAATATGAGTGACTATATTACAAATT
TAGAATCGCCTTTCTG
Protein Sequence 
>gi|82524431|ref|YP_406026.1| IpgB2 [Shigella dysenteriae Sd197] MIIMLGTSFNNFGISLSHKRYFSGKVDEIIRCTMGKRIVKISSTKINTSILSSVSEQIGENITDWKNDEKKVYVSRVVNQCIDKFCAEHSREIGDNLRKQIFKQVEKDYRISLDINAAQSSINHLVSGSSYFKKKMDELCEGMNRSVKNDTTSNVVNLISDQFFEKNVQYIDLKKLRGNMSDYITNLESPF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: ipgB2 mutant had entry into polarized cells reduced by 70% compared to the wild-type (Hachani et al., 2008).
References
Hachani et al., 2008: Hachani A, Biskri L, Rossi G, Marty A, Ménard R, Sansonetti P, Parsot C, Van Nhieu GT, Bernardini ML, Allaoui A. IpgB1 and IpgB2, two homologous effectors secreted via the Mxi-Spa type III secretion apparatus, cooperate to mediate polarized cell invasion and inflammatory potential of Shigella flexenri. Microbes and infection / Institut Pasteur. 2008; 10(3); 260-268. [PubMed: 18316224].