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ospF from Shigella dysenteriae Sd197

Victor ID 1484
Gene Name ospF from Shigella dysenteriae Sd197
Sequence Strain (Species/Organism) Shigella dysenteriae Sd197
NCBI Gene ID 3776469
NCBI Protein GI 82524419
Locus Tag SDY_P013
Protein Accession YP_406014.1
Other Database IDs UniProtKB-ID: OSPF_SHIDS
UniRef100: UniRef100_Q327I2
UniRef90: UniRef90_Q31SR9
UniRef50: UniRef50_Q327I2
UniParc: UPI00005E399B
EMBL: CP000035
EMBL-CDS: ABB64526.1
RefSeq_NT: NC_007607.1
EnsemblGenome: EBESCG00000084076
EnsemblGenome_TRS: EBESCT00000085030
EnsemblGenome_PRO: EBESCP00000081854
GenomeReviews: CP000035_GR
KEGG: sdy:SDY_P013
eggNOG: NOG26011
HOGENOM: HBG673220
OMA: ESDVHPE
ProtClustDB: CLSK862802
BioCyc: SDYS300267:SDY_P013-MONOMER
Taxonomy ID 300267
Plasmid No pSD1_197
Gene Starting Position 10900
Gene Ending Position 11619
Gene Strand (Orientation) -
Protein Name OspF
DNA Sequence 
>gi|82524407:10900-11619 Shigella dysenteriae Sd197 plasmid pSD1_197, complete sequence
TCTACTCTATCATCAAACGATAAAATGGTTCCTCTCGTAACATTTGCTCTTGCCTTTCACTTCCATTTCG
ATCGCTTCGTAGTTCATTACGATAGCTGACATATTTCCAGTCTTCAGGTCTAACATCTGACGCCGGATAC
TCCCCGGGAGCGATTTTGCTTCTTAATAGATTAGACTCGAGACACATTATAAATTGTCGTATTTTATGAA
GTAATAAAGCACTATATTGCGAGCATTCCTGATCTGATTTTACATATAGCGTAAACTGAGCTCCTATCCC
CACACGAGATTGCTGAGAAACTCGATTCATATCAGTTATCTTCCATTTATCTATAGGACTGTCCTCTGAA
AATAATAAACCAGACAAAATTTGGAATGCCAGAGGAACTTGCTCCCTAGCTATACTAATATGAAACTTGT
CCCCAACAAAATCCCCCTTACTCTGAGGATTTTCACGACATGCATGAATAAACACATCTCCACTATGGTT
CACAATCTGGAATCCTTGGTACATGACAGAAAAAAATTGACATATATCAGAGTAATTTGGCACGTTCGAT
GCTACTTTGAAATAGTACGCTGGGTATTGCCGTATTTGGTTGTACAATATATTGAAGTTATTTTTCAATC
TTTCATTCGCAGAAAGCATCTGCGGTATTTCAGACCTCACAACATTCAAAGAATCTAAATTTAGTTTTAG
ACAGGGCTTTTTTATGGGCA
Protein Sequence 
>gi|82524419|ref|YP_406014.1| OspF [Shigella dysenteriae Sd197] MPIKKPCLKLNLDSLNVVRSEIPQMLSANERLKNNFNILYNQIRQYPAYYFKVASNVPNYSDICQFFSVMYQGFQIVNHSGDVFIHACRENPQSKGDFVGDKFHISIAREQVPLAFQILSGLLFSEDSPIDKWKITDMNRVSQQSRVGIGAQFTLYVKSDQECSQYSALLLHKIRQFIMCLESNLLRSKIAPGEYPASDVRPEDWKYVSYRNELRSDRNGSERQEQMLREEPFYRLMIE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: ospF mutants had reduced PMN transepithelial migration when compared to wild-type infection, PMN transepithelial migration is necessary for virulence of Shigella (Zurawski et al., 2006).
References
Zurawski et al., 2006: Zurawski DV, Mitsuhata C, Mumy KL, McCormick BA, Maurelli AT. OspF and OspC1 are Shigella flexneri type III secretion system effectors that are required for postinvasion aspects of virulence. Infection and immunity. 2006; 74(10); 5964-5976. [PubMed: 16988276].