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mmpL10

Victor ID 146
Gene Name mmpL10
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 886068
NCBI Protein GI 15608323
Locus Tag Rv1183
Protein Accession NP_215699.1
Other Database IDs UniProtKB-ID: MMPLA_MYCTU
UniRef100: UniRef100_P65373
UniRef90: UniRef90_P65373
UniRef50: UniRef50_Q49619
UniParc: UPI000012F277
EMBL: BX842575
EMBL: AE000516
EMBL-CDS: CAA15860.1
EMBL-CDS: AAK45477.1
RefSeq_NT: NC_000962.2
RefSeq_NT: NC_002755.2
EnsemblGenome: EBMYCG00000001605
EnsemblGenome_TRS: EBMYCT00000001605
EnsemblGenome_PRO: EBMYCP00000001605
EnsemblGenome: EBMYCG00000072343
EnsemblGenome_TRS: EBMYCT00000072348
EnsemblGenome_PRO: EBMYCP00000070407
GenomeReviews: AE000516_GR
GenomeReview
Taxonomy ID 83332
Gene Starting Position 1321519
Gene Ending Position 1324527
Gene Strand (Orientation) +
Protein Name PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL10
DNA Sequence 
>gi|57116681:1321519-1324527 Mycobacterium tuberculosis H37Rv, complete genome
TGTGGTCGGCTGTTGGGTCGCGCTCGCCCTGGTACTGCCGATGGCGGTGCCTTCACTGGCGGAGATGGCT
CAGCGACATCCCGTCGCGGTCCTGCCTGCCGACGCGCCCTCCAGCGTCGCTGTTCGCCAGATGGCCGAGG
CGTTCCACGAATCCGGCTCCGAGAATATCTTGGTAGTGCTGCTCACCGACGAGAAAGGCTTGGGAGCGGC
GGACGAAAACGTCTACCACACATTGGTGGATCGTCTGCGAAACGACGCTAAAGACGTCGTGATGCTGCAG
GACTTCCTGACTACTCCGCCATTGCGTGAGGTGCTCGGTAGTAAAGATGGCAAGGCATGGATTCTGCCGA
TCGGTCTCGCGGGCGACCTGGGTACACCCAAGTCCTACCACGCTTACACCGACGTCGAACGCATCGTGAA
ACGAACTGTGGCCGGAACCACGTTGACGGCAAACGTGACAGGACCCGCAGCCACGGTGGCAGACCTGACC
GACGCTGGGGCTCGGGATCGGGCTTCAATCGAGCTGGCGATCGCCGTGATGTTGCTAGTCATCTTGATGG
TCATCTATCGCAACCCGGTTACCATGCTGTTGCCCCTGGTGACGATTGGCGCATCCTTGATGACCGCGCA
GGCGTTGGTTGCCGGCGTGTCGCTCGTCGGCGGTCTAGCCGTATCCAATCAAGCGATCGTGTTGCTCAGC
GCAATGATCGCTGGTGCGGGAACGGATTACGCCGTTTTCCTAATCAGCCGCTATCACGAGTATGTGCGGC
TCGGTGAGCATCCCGAGCGTGCCGTCCAGCGGGCGATGATGTCCGTCGGGAAGGTGATCGCCGCGTCCGC
GGCAACGGTCGGAATCACCTTCCTCGGCATGAGATTCGCCAAACTCGGTGTGTTCTCAACGGTTGGCCCG
GCTCTGGCGATCGGGATCGCGGTGTCGTTCTTGGCCGCGGTCACCCTGCTGCCCGCCATCCTGGTGCTGG
CCTCACCGCGCGGGTGGGTCGCACCGCGCGGTGAACGCATGGCGACATTCTGGCGGCGGGCCGGAACGCG
AATAGTGCGGCGGCCCAAAGCTTATCTAGGCGCCAGCTTGATTGGTCTGGTTGCATTGGCCAGCTGCGCG
AGCCTGGCTCACTTCAACTACGACGACCGCAAACAATTGCCGCCTTCGGATCCGAGTTCGGTTGGGTACG
CGGCAATGGAGCACCATTTCTCGGTGAATCAGACTATTCCTGAGTACTTGATCATCCACTCTGCACACGA
CCTGCGAACCCCGCGCGGCCTTGCCGACCTGGAGCAGCTGGCGCAACGTGTGAGCCAGATCCCAGGCGTT
GCCATGGTTCGCGGTGTGACCCGGCCAAACGGGGAAACCCTTGAACAGGCCCGGGCGACATACCAAGCCG
GCCAAGTTGGCAACCGGCTGGGCGGCGCGTCGCGAATGATCGATGAGCGCACCGGCGACCTGAATCGGCT
GGCATCGGGTGCCAACCTGTTGGCCGACAATCTCGGTGACGTTCGCGGTCAAGTCAGCCGGGCCGTTGCG
GGTGTCCGCAGCCTTGTCGACGCCCTCGCTTACATCCAGAACCAGTTCGGTGGCAACAAAACATTCAACG
AAATCGACAACGCTGCAAGGCTTGTCAGCAATATCCACGCGCTCGGTGACGCTCTGCAGGTAAACTTTGA
CGGTATCGCCAACAGTTTCGATTGGCTTGACTCTGTTGTCGCCGCTTTGGATACCAGCCCGGTCTGTGAC
AGCAACCCTATGTGTGGCAACGCGCGCGTTCAGTTTCACAAGCTGCAAACCGCACGTGACAATGGCACTC
TCGACAAGGTTGTCGGCCTGGCGCGTCAGCTGCAGTCCACGCGGTCACCGCAGACCGTGTCGGCGGTGGT
GAACGATCTGGGGCGATCGCTGAATTCGGTAGTCCGCTCGCTGAAATCACTGGGGTTGGACAATCCGGAC
GCCGCCCGGGCGCGCCTGATCAGCATGCAAAATGGAGCTAACGACCTCGCCAGCGCCGGTCGTCAGGTCG
CAGACGGCGTCCAGATGCTGGTCGACCAGACCAAGAACATGGGCATCGGGCTGAACCAGGCGTCAGCCTT
TCTGATGGCGATGGGCAACGATGCGTCGCAACCGTCGATGGCGGGTTTCAATGTCCCGCCGCAAGTGCTG
AAGTCCGAGGAGTTCAAAAAAGTCGCCCAGGCGTTCATCTCGCCAGACGGGCATACCGTGCGGTACTTCA
TTCAGACCGACCTCAACCCGTTCAGCACTGCGGCCATGGATCAGGTCAACACGATCATTGACACAGCCAA
AGGTGCACAGCCAAATACCTCCCTGGCTGACGCGTCGATATCAATGTCGGGTTACCCGGTCATGCTGAGG
GACATCCGCGATTACTACGAGCGCGATATGCGGCTCATCGTCGCTGTGACCGTCGTCGTGGTGATCCTGA
TCCTCATGGCACTGCTGCGTGCGATAGTGGCGCCGCTGTACCTGGTCGGTTCGGTGGTCATCTCGTACAT
GTCGGCGATCGGGCTTGGTGTGGTGGTGTTCCAGGTGTTCCTGGGGCAGGAATTGCACTGGAGTGTGCCC
GGCCTAGCGTTTGTGGTGCTGGTCGCCGTGGGTGCGGACTACAACATGCTGCTGGCGTCGCGGTTGCGGG
ACGAGTCGGCATTGGGAGTGCGTTCCAGCGTGATTCGCACGGTGCGTTGCACGGGCGGAGTGATCACGGC
AGCGGGTCTGATATTTGCCGCTTCGATGTCCGGCCTGCTGTTCTCCAGCATCGGAACCGTCGTCCAAGGC
GGCTTCATCATTGGGGTCGGGATCCTGATAGACACGTTCGTGGTGCGGACCATCACCGTGCCTGCCATGG
CCACGCTGCTCGGACGCGCAAGTTGGTGGCCCGGACACCCTTGGCAGCGGTGCGCACCCGAAGAAGGCCA
GATGTCAGCCCGGATGTCAGCGCGCACGAAGACGGTATTTCAAGCCGTGGCAGACGGATCAAAGCGGTA
Protein Sequence 
>gi|15608323|ref|NP_215699.1| transmembrane transport protein MmpL10 [Mycobacterium tuberculosis H37Rv] MVGCWVALALVLPMAVPSLAEMAQRHPVAVLPADAPSSVAVRQMAEAFHESGSENILVVLLTDEKGLGAADENVYHTLVDRLRNDAKDVVMLQDFLTTPPLREVLGSKDGKAWILPIGLAGDLGTPKSYHAYTDVERIVKRTVAGTTLTANVTGPAATVADLTDAGARDRASIELAIAVMLLVILMVIYRNPVTMLLPLVTIGASLMTAQALVAGVSLVGGLAVSNQAIVLLSAMIAGAGTDYAVFLISRYHEYVRLGEHPERAVQRAMMSVGKVIAASAATVGITFLGMRFAKLGVFSTVGPALAIGIAVSFLAAVTLLPAILVLASPRGWVAPRGERMATFWRRAGTRIVRRPKAYLGASLIGLVALASCASLAHFNYDDRKQLPPSDPSSVGYAAMEHHFSVNQTIPEYLIIHSAHDLRTPRGLADLEQLAQRVSQIPGVAMVRGVTRPNGETLEQARATYQAGQVGNRLGGASRMIDERTGDLNRLASGANLLADNLGDVRGQVSRAVAGVRSLVDALAYIQNQFGGNKTFNEIDNAARLVSNIHALGDALQVNFDGIANSFDWLDSVVAALDTSPVCDSNPMCGNARVQFHKLQTARDNGTLDKVVGLARQLQSTRSPQTVSAVVNDLGRSLNSVVRSLKSLGLDNPDAARARLISMQNGANDLASAGRQVADGVQMLVDQTKNMGIGLNQASAFLMAMGNDASQPSMAGFNVPPQVLKSEEFKKVAQAFISPDGHTVRYFIQTDLNPFSTAAMDQVNTIIDTAKGAQPNTSLADASISMSGYPVMLRDIRDYYERDMRLIVAVTVVVVILILMALLRAIVAPLYLVGSVVISYMSAIGLGVVVFQVFLGQELHWSVPGLAFVVLVAVGADYNMLLASRLRDESALGVRSSVIRTVRCTGGVITAAGLIFAASMSGLLFSSIGTVVQGGFIIGVGILIDTFVVRTITVPAMATLLGRASWWPGHPWQRCAPEEGQMSARMSARTKTVFQAVADGSKR
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: attenuated in mice (Sassetti and Rubin, 2003).
COG COG2409R, under R: General function prediction only
References
Sassetti and Rubin, 2003: Sassetti CM, Rubin EJ. Genetic requirements for mycobacterial survival during infection. Proceedings of the National Academy of Sciences of the United States of America. 2003; 100(22); 12989-12994. [PubMed: 14569030].