Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

plcB from Listeria monocytogenes str. 4b F2365

Victor ID 1419
Gene Name plcB from Listeria monocytogenes str. 4b F2365
Sequence Strain (Species/Organism) Listeria monocytogenes str. 4b F2365
NCBI Gene ID 2797078
NCBI Protein GI 46906437
Locus Tag LMOf2365_0216
Protein Accession YP_012826.1
Other Database IDs UniProtKB-ID: Q724K8_LISMF
UniRef100: UniRef100_Q724K8
UniRef90: UniRef90_P33378
UniRef50: UniRef50_P33378
UniParc: UPI000035CD1A
EMBL: AE017262
EMBL-CDS: AAT03003.1
RefSeq_NT: NC_002973.6
HSSP: P09598
GenomeReviews: AE017262_GR
KEGG: lmf:LMOf2365_0216
TIGR: LMOf2365_0216
eggNOG: NOG09647
HOGENOM: HBG340118
OMA: RANLMNE
ProtClustDB: CLSK895085
BioCyc: LMON265669:LMOF2365_0216-MONOMER
Taxonomy ID 265669
Gene Starting Position 216707
Gene Ending Position 217549
Gene Strand (Orientation) +
Protein Name phospholipase C
DNA Sequence 
>gi|85700163:216707-217549 Listeria monocytogenes str. 4b F2365, complete genome
TATGTGCTTGACCGCAAGTGTTCTAGTCTTTCCTGTAACGATAAAAGCAAGTGCCTGTTGTGATGAATAT
CTAAAGCCCCCCGCAGCTCCGCATGATATTGACAGCAAATTACCGCATAAACTTAGTTGGTCCGCGGATA
ATCCGACAAATACTGAGGTAAATACGCACTATTGGCTTTTTAAACAAGCGGAAAAAATACTAGCTAAAGA
TGTAGATCATATGCGAGCTAATTTAATGAATGAACTTAAAAATTTCGACAAACAAATTGCTCAAGGAATA
TATGACGCGGATCATAAAAATCCATATTATGATACTAGTACGTTTTTATCTCATTTTTATAATCCTGATA
AAGATAATACTTATTTGCCAGGTTTTGCTAATGCGAAAATAACAGGAGCCAAGTATTTTAATCAATCGGT
GGCTGATTACCGAGAAGGGAAATTTGACACAGCATTTTATAAATTGGGCCTAGCAATCCATTATTATACG
GATATTAGTCAACCTATGCACGCCAATAATTTTACCGCAATATCCTATCCACCAGGCTACCACTGTGCAT
ATGAAAATTACGTAGATACCATTAAACACAATTATCAAGCAACAGAAGACATGGTAGTGAAAAGATTTTG
CTCAAATGACGTGAAAGAATGGCTCTATGAAAATGCGAAAAGGGCGAAAGCGGACTATCCGAAAATAGTC
AATGCGAAAACTAAAAAATCATACTTAGTAGGAAATTCCGAATGGAAAAAGGATACAGTGGAACCTACTG
GAGCTAGACTAAGAGATTCACAGCAAACTTTGGCAGGCTTTTTAGAATTTTGGTCTAAAAAAACAAATGA
ATA
Protein Sequence 
>gi|46906437|ref|YP_012826.1| phospholipase C [Listeria monocytogenes serotype 4b str. F2365] MCLTASVLVFPVTIKASACCDEYLKPPAAPHDIDSKLPHKLSWSADNPTNTEVNTHYWLFKQAEKILAKDVDHMRANLMNELKNFDKQIAQGIYDADHKNPYYDTSTFLSHFYNPDKDNTYLPGFANAKITGAKYFNQSVADYREGKFDTAFYKLGLAIHYYTDISQPMHANNFTAISYPPGYHCAYENYVDTIKHNYQATEDMVVKRFCSNDVKEWLYENAKRAKADYPKIVNAKTKKSYLVGNSEWKKDTVEPTGARLRDSQQTLAGFLEFWSKKTNE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: deletion mutants showed reduced virulence in mice, escape from vacuole and cell-to-cell spread (Smith et al., 1995).
References
Smith et al., 1995: Smith GA, Marquis H, Jones S, Johnston NC, Portnoy DA, Goldfine H. The two distinct phospholipases C of Listeria monocytogenes have overlapping roles in escape from a vacuole and cell-to-cell spread. Infection and immunity. 1995; 63(11); 4231-4237. [PubMed: 7591052].