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pks16

Victor ID 141
Gene Name pks16
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 886035
NCBI Protein GI 15608153
Locus Tag Rv1013
Protein Accession NP_215529.1
Other Database IDs UniProtKB-ID: Y1013_MYCTU
UniRef100: UniRef100_O05598
UniRef90: UniRef90_A0R3D6
UniRef50: UniRef50_A0R3D6
UniParc: UPI00000D4F22
EMBL: BX842575
EMBL-CDS: CAB08159.1
RefSeq_NT: NC_000962.2
EnsemblGenome: EBMYCG00000003126
EnsemblGenome_TRS: EBMYCT00000003128
EnsemblGenome_PRO: EBMYCP00000003128
GenomeReviews: AL123456_GR
KEGG: mtu:Rv1013
TubercuList: Rv1013
HOGENOM: HBG547964
OMA: VIIMGGR
ProtClustDB: PRK07768
Taxonomy ID 83332
Gene Starting Position 1131624
Gene Ending Position 1133258
Gene Strand (Orientation) +
Protein Name acyl-CoA synthetase
DNA Sequence 
>gi|57116681:1131624-1133258 Mycobacterium tuberculosis H37Rv, complete genome
CTTGAGCAGGTTCACCGAGAAGATGTTCCACAATGCCCGCACCGCGACGACGGGCATGGTCACAGGTGAA
CCGCACATGCCCGTCCGCCACACCTGGGGCGAGGTCCATGAGCGTGCTCGTTGCATCGCGGGCGGCCTGG
CCGCCGCGGGTGTCGGTCTTGGTGACGTTGTTGGGGTGCTGGCCGGCTTCCCGGTGGAGATCGCCCCCAC
GGCGCAGGCCCTGTGGATGCGCGGGGCCAGCCTGACCATGCTGCACCAGCCCACACCGCGCACCGACTTG
GCCGTGTGGGCCGAGGACACCATGACCGTCATCGGCATGATCGAGGCCAAGGCCGTGATCGTCTCCGAGC
CCTTCCTCGTGGCCATTCCCATCCTTGAGCAGAAAGGCATGCAGGTCCTTACCGTCGCTGACCTTTTGGC
GTCGGATCCGATCGGCCCCATCGAGGTCGGCGAGGACGACCTGGCGTTGATGCAGCTGACGTCCGGATCT
ACCGGCTCCCCTAAAGCCGTCCAGATCACCCACCGCAACATCTACTCCAACGCCGAGGCAATGTTCGTCG
GCGCCCAGTATGACGTCGACAAGGACGTCATGGTCAGCTGGTTGCCCTGCTTCCATGACATGGGCATGGT
GGGCTTCTTGACTATCCCGATGTTCTTCGGTGCGGAGCTGGTCAAGGTCACGCCAATGGACTTCCTGCGC
GACACGCTGCTGTGGGCGAAGCTCATCGACAAGTACCAGGGCACCATGACCGCGGCGCCCAACTTCGCCT
ACGCGCTGCTCGCCAAGCGGTTGCGGCGCCAGGCCAAGCCCGGCGACTTCGATCTGTCGACCCTACGCTT
CGCGCTGTCCGGCGCCGAGCCCGTCGAACCCGCCGACGTCGAGGACCTGCTCGACGCGGGCAAGCCGTTC
GGCCTGAGGCCCTCAGCGATCCTGCCGGCCTACGGCATGGCCGAGACCACGCTGGCGGTGTCCTTCTCGG
AGTGCAACGCCGGCCTCGTCGTGGACGAGGTTGACGCCGACCTGCTGGCGGCTCTGCGCCGGGCCGTTCC
CGCCACCAAAGGCAATACCCGCAGGCTGGCCACGCTAGGTCCGCTGCTGCAGGACCTAGAGGCCCGCATC
ATCGACGAACAGGGCGATGTCATGCCCGCCCGCGGCGTGGGTGTCATCGAGCTGCGCGGCGAGTCGCTAA
CTCCCGGCTACCTGACTATGGGTGGCTTCATCCCGGCCCAAGACGAGCATGGCTGGTACGACACGGGCGA
CCTCGGCTACCTCACCGAGGAGGGCCACGTGGTGGTATGTGGCCGCGTCAAGGATGTCATCATCATGGCC
GGGCGCAATATTTACCCGACCGACATCGAGCGGGCGGCCGGCCGCGTCGACGGCGTTCGTCCGGGTTGCG
CGGTGGCCGTGCGTCTCGATGCCGGACATTCGCGCGAATCCTTTGCCGTCGCGGTCGAGTCGAACGCCTT
CGAGGATCCCGCCGAGGTTCGTCGCATCGAGCATCAAGTGGCCCACGAGGTGGTTGCCGAGGTCGACGTG
CGGCCTCGCAACGTCGTGGTTCTTGGACCCGGGACCATTCCGAAGACGCCGTCGGGCAAGCTGCGTCGGG
CCAACTCCGTCACCCTGGTCACCTA
Protein Sequence 
>gi|15608153|ref|NP_215529.1| polyketide synthase [Mycobacterium tuberculosis H37Rv] MSRFTEKMFHNARTATTGMVTGEPHMPVRHTWGEVHERARCIAGGLAAAGVGLGDVVGVLAGFPVEIAPTAQALWMRGASLTMLHQPTPRTDLAVWAEDTMTVIGMIEAKAVIVSEPFLVAIPILEQKGMQVLTVADLLASDPIGPIEVGEDDLALMQLTSGSTGSPKAVQITHRNIYSNAEAMFVGAQYDVDKDVMVSWLPCFHDMGMVGFLTIPMFFGAELVKVTPMDFLRDTLLWAKLIDKYQGTMTAAPNFAYALLAKRLRRQAKPGDFDLSTLRFALSGAEPVEPADVEDLLDAGKPFGLRPSAILPAYGMAETTLAVSFSECNAGLVVDEVDADLLAALRRAVPATKGNTRRLATLGPLLQDLEARIIDEQGDVMPARGVGVIELRGESLTPGYLTMGGFIPAQDEHGWYDTGDLGYLTEEGHVVVCGRVKDVIIMAGRNIYPTDIERAAGRVDGVRPGCAVAVRLDAGHSRESFAVAVESNAFEDPAEVRRIEHQVAHEVVAEVDVRPRNVVVLGPGTIPKTPSGKLRRANSVTLVT
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: attenuated in mice (Sassetti and Rubin, 2003).
COG COG0318IQ, under I: Lipid transport and metabolism; Q: Secondary metabolites biosynthesis, transport and catabolism
References
Sassetti and Rubin, 2003: Sassetti CM, Rubin EJ. Genetic requirements for mycobacterial survival during infection. Proceedings of the National Academy of Sciences of the United States of America. 2003; 100(22); 12989-12994. [PubMed: 14569030].