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BMEII1037

Victor ID 1397
Gene Name BMEII1037
Sequence Strain (Species/Organism) Brucella
NCBI Gene ID 1198809
NCBI Protein GI 17989382
Locus Tag BMEII1037
Protein Accession NP_542015.1
Other Database IDs UniProtKB-ID: Q8YB63_BRUME
UniRef100: UniRef100_C9V6R2
UniRef90: UniRef90_A9MDW3
UniRef50: UniRef50_B2SD05
UniParc: UPI00000586FA
EMBL: AE008918
EMBL-CDS: AAL54279.1
RefSeq_NT: NC_003318.1
GenomeReviews: AE008918_GR
KEGG: bme:BMEII1037
NMPDR: fig|224914.1.peg.3097
HOGENOM: HBG634529
OMA: QVVMEER
ProtClustDB: CLSK899041
BioCyc: BMEL224914:BMEII1037-MONOMER
Taxonomy ID 224914
Chromosome No II
Gene Starting Position 1077206
Gene Ending Position 1078600
Gene Strand (Orientation) -
Protein Name ZINC PROTEASE
DNA Sequence 
>gi|17988344:1077206-1078600 Brucella melitensis bv. 1 str. 16M chromosome chromosome II, complete sequence
ATCACTGGATCGCTCCTCCCGCACCGCTTGCGCTTGCGTCATTTGCTGGCGCGTTCGGCTTCTTGCGGGC
GCTTTCTGCTTCGGTATCGGGCGGCAGAAGATAGCTCGTCACGGCTTGGTCCTTGACCAGATAACGCCTG
GCTACATCCTTGATCTGATCGACGGTTACGCTTTTGATGAGATCGGGCCATTTCTGGATATCATCCACCG
TCTGGCCAACCGAAAGCGCCGAACCATAGATGCGCGCCATGCCGGTCTGGCTGTCGCGCGCGAAAATCAC
CGCCTTGAGGAAACGGTTGCGCGCCTGATCGAGTTCAGCCTGTGTGACACCATCCCGGATGATACGATCC
ACTTGCGCTGCGACAGCTTTTTCGACATCGCCAAGCGATGCGCCGTTGCGCGGTACGCCATAGACCGAGA
ACGTGCCGTCATCCAGCGCATCGCCGTCATAGCTTGCGCCTGTTTCAGCAGCGATGCCCTGCTTGACGAT
CAATTGCTGGTAAAGCCGCGAAAGCTGCGACCCGCCCAGTATTTCACTCAAAAGATCAAGCGCCGGCGCA
TCGCCGGGTTTCACATTCGCAAATCGCTTTTCATTGGCATAGGAAGGCACCAGCCATGAAATGCGGAAGG
AGGGTGTGCTGACACGCTCATCATGCAGGGTTACGACACGGGCTGCATGTTTCGCCGGTTCCTGCGGGCG
TTCGCGCAGCAAAACCTCGGCGCGTTTGTGGACGTTCGCCCAGGTCTTCATCGCAAGCTCGCGCACACGC
TCCGGCGTCACATCACCCGCAATCACCAGCGTCGCATTATTGGGCGTATAATATTGATTGTAGAAATCGA
TGGCATTCTTCAGGCTCAGCTTTTCCATTTCCTGCTGCCAGCCGATCACCGGCTTGCGATAGGGATGGTT
ATAGAAAAGCACAGCATCAGTGTTTTCCATGAGCATTGCGCCAGGGTTGGAATCGATGCGCATCCGGCGC
TCTTCCAGAATGACCTCGCGCTCGGTCTTCACCGCTTCCTCGTCCAGAACCAGATTTTCCATCCGGTCGG
ATTCAAAATCCATCACCATTTCCAGCGCTTCCGGCGAAACACGCTGGAAGTAGGCCGTATAATCATAAGA
GGTGAAAGCGTTTTCCTGCCCGCCGATTGAGGCGATTCTGGCCGAAAACTCGCCTGCCGGGTGGTTTTTG
GTGCCCTTGAACATCAGATGTTCGAGAAAATGCGCAATGCCCGAAACGCCGGGGGCTTCATCCGCCGCAC
CGACATGATACCAGACCATCTGGGTGACGACAGGGGCACGGTGATCGGGAATGACCACCACCTGCATACC
GTTTGGAAGCGTGAAATTGCTGACCCCGTCCAACCGGGAAATCTCCGGCAGGGCTGCCTGCGCCA
Protein Sequence 
>gi|17989382|ref|NP_542015.1| zinc protease [Brucella melitensis bv. 1 str. 16M] MAQAALPEISRLDGVSNFTLPNGMQVVVIPDHRAPVVTQMVWYHVGAADEAPGVSGIAHFLEHLMFKGTKNHPAGEFSARIASIGGQENAFTSYDYTAYFQRVSPEALEMVMDFESDRMENLVLDEEAVKTEREVILEERRMRIDSNPGAMLMENTDAVLFYNHPYRKPVIGWQQEMEKLSLKNAIDFYNQYYTPNNATLVIAGDVTPERVRELAMKTWANVHKRAEVLLRERPQEPAKHAARVVTLHDERVSTPSFRISWLVPSYANEKRFANVKPGDAPALDLLSEILGGSQLSRLYQQLIVKQGIAAETGASYDGDALDDGTFSVYGVPRNGASLGDVEKAVAAQVDRIIRDGVTQAELDQARNRFLKAVIFARDSQTGMARIYGSALSVGQTVDDIQKWPDLIKSVTVDQIKDVARRYLVKDQAVTSYLLPPDTEAESARKKPNAPANDASASGAGGAIQ
Molecule Role Virulence factor
Molecule Role Annotation FUNCTIONAL GROUP: Other genes (Delrue et al., 2004).

FUNCTION: Zinc protease (Delrue et al., 2004).

MUTATION: Attenuated in Mice (Delrue et al., 2004).
COG COG0612R, under R: General function prediction only
References
Delrue et al., 2004: Delrue RM, Lestrate P, Tibor A, Letesson JJ, De Bolle X. Brucella pathogenesis, genes identified from random large-scale screens. FEMS microbiology letters. 2004; 231(1); 1-12. [PubMed: 14979322].