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wbpW from Brucella melitensis bv. 1 str. 16M

Victor ID 1390
Gene Name wbpW from Brucella melitensis bv. 1 str. 16M
Sequence Strain (Species/Organism) Brucella melitensis bv. 1 str. 16M
NCBI Gene ID 1198672
NCBI Protein GI 17989245
Locus Tag BMEII0900
Protein Accession NP_541878.1
Other Database IDs UniProtKB-ID: D0B6G4_BRUME
UniRef100: UniRef100_D0B6G4
UniRef90: UniRef90_B2SBP8
UniRef50: UniRef50_B3RC83
UniParc: UPI0000058671
EMBL: GG703779
EMBL-CDS: EEW87206.1
RefSeq_NT: NC_003318.1
OMA: CFKAGVF
Taxonomy ID 224914
Chromosome No II
Gene Starting Position 942429
Gene Ending Position 943844
Gene Strand (Orientation) +
Protein Name MANNOSE-6-PHOSPHATE ISOMERASE / MANNOSE-1-PHOSPHATE GUANYLYL TRANSFERASE (GDP)
DNA Sequence 
>gi|17988344:942429-943844 Brucella melitensis bv. 1 str. 16M chromosome chromosome II, complete sequence
CATGAGTTTCATACCGGTAATTATCAGCGGGGGATCGGGTTCAAGGCTTTGGCCGCTTTCGCGGGATGCA
CATCCAAAACCCTTTATCAAACTGCCGGATGGCGAAACACTCATCGGCAAGACCTATGCGCGCGCTTCGC
GCCTTGTAAACGCCGAACAGATCCTTACGGTTACGAACCGCGATTTTCTTTTCCTGACGCTCGACGCTTA
TGCGGCGGCAGGTGCCGCGCAGATGGAAAACACTTTCCTTCTGGAGCCGCTTGGCCGCGACACCGCGCCC
GCAGTGGCGCTTGCCGCCCTTCATGCCGCTGAAGCCTATGGGCCGGATGCCACGCTTCTGGTCATGCCGG
CCGATCACCTGATCGAGGATGAACAAGCCTTCGCGGAAGCGGTTGCGAAAGCGCGCGCGCTTGCCGAGGC
AGGGCGCATCGTCACCTTCGGCATTGTGCCGGATCGGCCCGAGACCGGCTTCGGCTATATCGAAGTGCAA
GGTACGGATGTTCAGCGATTTGTCGAAAAGCCGGATGAGGCCACCGCCCAGACCTATGTGGAAAGCGGAC
GCTATTTCTGGAATTCCGGCATGTTCTGCTTCAAGGCATTGAGCATGATCGACGCCATGCAGCGTTACGC
ACCGCAGGTACTGGCAGGCGCTAGGGCTGCCCTCGCCCAGGCCCGGCGTGGCAATAACGGCGAGACCAAA
ACCCTTGAAATCGCCAGGGACGAGTTTGCCGCAACGCCTGCCATTTCCATCGACTACGCAGTCATGGAAA
AGGCGGACAATATGGCCTGCGTGCCCGTTTCCTGCGGCTGGTCGGATATCGGCTCATGGGCGGCGATGGC
CGATCTCGTGACACCCGATGAAAACGGCAATCGCCTGCGCGGAGAAACTGTTCTGGAAGATACGACCAAC
AGTTTCGTCCTTTCTGAAACCCGTCTGGTGAGCCTTGTCGGTGTGCATGATCTTCTCGTGGTTGACACGC
CGGACGCCCTTCTCGTCGCTCATCGCGACAAAGCGCAGGAAGTACGCAGCGTTTTCAACAAATTGCGCAA
GCAAGGTCATGAAGCTGCAAAGCTGCACCGCACAGCCCATCGCCCATGGGGCACCTATACCGTGCTGGAA
GAGGGCGACGGCTTCAAGATCAAACGGATCGAGGTAAAGCCAGGGCGGCGCCTCAGCCTTCAGGCCCATC
ACCACCGCTCCGAACACTGGATCGTGGTGTCCGGCACGGCAAAGGTGACGAATGGCGACCGGGAAATCCT
GCTCACCACCAATCAGTCAACCTATATTCCCTGCGGTTTCCGCCACCGGTTGGAAAATCCCGGTATTTTG
CCCCTCGTCCTGATCGAGGTGCAGAGCGGCGAATATCTCGGTGAAGACGACATCGTGCGCTATGACGATG
TTTACGGACGCGTTTG
Protein Sequence 
>gi|17989245|ref|NP_541878.1| mannose-6-phosphate isomerase / mannose-1-phosphate guanylyl transferase (GDP) [Brucella melitensis bv. 1 str. 16M] MSFIPVIISGGSGSRLWPLSRDAHPKPFIKLPDGETLIGKTYARASRLVNAEQILTVTNRDFLFLTLDAYAAAGAAQMENTFLLEPLGRDTAPAVALAALHAAEAYGPDATLLVMPADHLIEDEQAFAEAVAKARALAEAGRIVTFGIVPDRPETGFGYIEVQGTDVQRFVEKPDEATAQTYVESGRYFWNSGMFCFKALSMIDAMQRYAPQVLAGARAALAQARRGNNGETKTLEIARDEFAATPAISIDYAVMEKADNMACVPVSCGWSDIGSWAAMADLVTPDENGNRLRGETVLEDTTNSFVLSETRLVSLVGVHDLLVVDTPDALLVAHRDKAQEVRSVFNKLRKQGHEAAKLHRTAHRPWGTYTVLEEGDGFKIKRIEVKPGRRLSLQAHHHRSEHWIVVSGTAKVTNGDREILLTTNQSTYIPCGFRHRLENPGILPLVLIEVQSGEYLGEDDIVRYDDVYGRV
Molecule Role Virulence factor
Molecule Role Annotation FUNCTIONAL GROUP: "Classical virulence factors", Envelope molecules, Lipopolysaccharide (Delrue et al., 2004).

FUNCTION: O-chain biosynthesis (Delrue et al., 2004).

MUTATION: Attenuated in Macrophages (Delrue et al., 2004).
COG COG0836M, under M: Cell wall/membrane/envelope biogenesis
References
Delrue et al., 2004: Delrue RM, Lestrate P, Tibor A, Letesson JJ, De Bolle X. Brucella pathogenesis, genes identified from random large-scale screens. FEMS microbiology letters. 2004; 231(1); 1-12. [PubMed: 14979322].