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glpK from Brucella melitensis bv. 1 str. 16M

Victor ID 1387
Gene Name glpK from Brucella melitensis bv. 1 str. 16M
Sequence Strain (Species/Organism) Brucella melitensis bv. 1 str. 16M
NCBI Gene ID 1198595
NCBI Protein GI 17989168
Locus Tag BMEII0823
Protein Accession NP_541801.1
Other Database IDs UniProtKB-ID: GLPK_BRUME
UniRef100: UniRef100_A9MB89
UniRef90: UniRef90_A9MB89
UniRef50: UniRef50_A4J8E6
UniParc: UPI0000EADFBA
EMBL: AE008918
EMBL-CDS: AAL54065.1
EMBL-CDS: AAL54066.1
RefSeq_NT: NC_003318.1
OMA: GWVEHEP
ProtClustDB: CLSK2303103
BioCyc: BMEL224914:BMEII0823-MONOMER
BioCyc: BMEL224914:BMEII0824-MONOMER
Taxonomy ID 224914
Chromosome No II
Gene Starting Position 857089
Gene Ending Position 857256
Gene Strand (Orientation) +
Protein Name GLYCEROL KINASE
DNA Sequence 
>gi|17988344:857089-857256 Brucella melitensis bv. 1 str. 16M chromosome chromosome II, complete sequence
AATGAGCGGATATATTCTGGCTATCGATCAGGGAACCACCTCCACAAGGTCGATGCTGTTCGACAGGAAT
ATGCGGGTCGTGGGGTTGGGGCAGCAGGAATTTACGCAGCATTTTCCTTCCTCCGGCTGGGTGGAGCACG
ATGCGGAAGAAATCTGGAAATCGGTGTA
Protein Sequence 
>gi|17989168|ref|NP_541801.1| glycerol kinase, partial [Brucella melitensis bv. 1 str. 16M] MSGYILAIDQGTTSTRSMLFDRNMRVVGLGQQEFTQHFPSSGWVEHDAEEIWKSV
Molecule Role Virulence factor
Molecule Role Annotation FUNCTION: Key enzyme in the regulation of glycerol uptake and metabolism(UniProt: Q8FWK8).

CATALYTIC ACTIVITY: ATP + glycerol = ADP + sn-glycerol 3-phosphate(UniProt: Q8FWK8).

PATHWAY: Glycerol utilization; first (rate-limiting) step(UniProt: Q8FWK8).

SIMILARITY: Belongs to the FGGY kinase family(UniProt: Q8FWK8).

MUTATION: Attenuated in Mice, Macrophages, HeLa (Delrue et al., 2004).
COG COG0554C, under C: Energy production and conversion
References
Delrue et al., 2004: Delrue RM, Lestrate P, Tibor A, Letesson JJ, De Bolle X. Brucella pathogenesis, genes identified from random large-scale screens. FEMS microbiology letters. 2004; 231(1); 1-12. [PubMed: 14979322].