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pyrC from Brucella melitensis bv. 1 str. 16M

Victor ID 1379
Gene Name pyrC from Brucella melitensis bv. 1 str. 16M
Sequence Strain (Species/Organism) Brucella melitensis bv. 1 str. 16M
NCBI Gene ID 1198441
NCBI Protein GI 17989014
Locus Tag BMEII0669
Protein Accession NP_541647.1
Other Database IDs UniProtKB-ID: D0B736_BRUME
UniRef100: UniRef100_D0B736
UniRef90: UniRef90_A9MBP0
UniRef50: UniRef50_D8JSX1
UniParc: UPI000005858C
EMBL: GG703779
EMBL-CDS: EEW87428.1
RefSeq_NT: NC_003318.1
OMA: GVMNEGE
Taxonomy ID 224914
Chromosome No II
Gene Starting Position 702975
Gene Ending Position 704261
Gene Strand (Orientation) -
Protein Name dihydroorotase
DNA Sequence 
>gi|17988344:702975-704261 Brucella melitensis bv. 1 str. 16M chromosome chromosome II, complete sequence
TTCAAGCCGAATAAACGGTCTTGCCCGCTACAATCGTGCGAACCACGCGCCCCTGGAACCGCGCACTTTC
AAAGCAGCTATTCTTGGAGCGCGAATGCAGGTCTTCCTCCCGCACGACCCATGGTTCTTCCAGATCGACA
ATGGCGATATCCGCGCTTGCGCCCGGTTTCAGCGTACCGGCATTCAGGCCGAATATTTTTGCTGGCGCCG
TGGAAAGCACCTCGACCAGCCGCAGAAGCGGAATATTGTCATTATGATAGAGACGAAGTGCCGCCGCGAG
CAGCGTTTCCAGACCGATTGCGCCTGCTTCGGCATCTGAAAAGGGCAGGCGCTTGGTATCCACATCCTGC
GGGTCATGTGCCGAAACCACGATGTCGATGGTGCCGTTTTTCACGGCTTCCACCATGGCGAGCCGGTCTT
CCTCGCCGCGCAGCGGCGGCGACAGGCGGAAGAAGGTGCGGAACTCGCCGATATCGTTCTCGTTGAGCGA
CAGATGGTTGATCGACACGCCCGCCGTGACGTTCGTGCCCAGATCCTTGGCGCGGCGCATGGCGTCCGCC
GACATGGCGCAGGAAAGCTGCGCGGCGTGGTAGCGGCTTCGGGTGAGGGCCGCAAGACGCAGATCACGCT
CCAGCGGAATCACTTCCGCTTCCCGCGGCGTGCCGGAAAGGCCAAGCCAGCTTGCAAACAGGCCTTCATT
CATCACGCCGTTTGCGCCGAGCAAAGGATCGCGTGTTTCGCAGGCGATGACGGCGTTGAAATCGCGCGCA
TAGGTGAGGGCGCGGCGCATGATCTGCGTATTGGCGATAGTATTGCGGCCTTCGGTGAAGGCAACCGCAC
CGGCTGCCCGCAGCAGGCCGAATTCGGTCATTTCCTCGCCGTGCAGGCCCTTGGTGATGGCGGCGGCGGG
ATGGACATTGACGATGGCCGTGTCGCGCGCTGTGCGCTTGACGAATTCCACCAGCGCCACATCGTCGATC
ACCGGATCGGTGTCCGGCATCATGATGATGGAGGTGACGCCGCCTGCCGCAGCCGCCCGGCTTGCCGAAG
CGATTGTTTCGCGGTGTTCAGCCCCCGGTTCACCGATGAAGACCCGCGAATCCACGAGACCCGGCATCAC
AGCCTTGCCATCCAGATCGACAATTTCAGCACCTTCCGGCGCGCCCTGATTACGGGCCTCGCTGCCAGCG
GCGACGATTTTGCCGTTTTCGATCAGAAGGCTGCCGGTTTCATCAAGGCCGCGTGATGGATCGACGATCC
GGGCGTTTTCAAACAGGATCGCGCTCA
Protein Sequence 
>gi|17989014|ref|NP_541647.1| dihydroorotase [Brucella melitensis bv. 1 str. 16M] MSAILFENARIVDPSRGLDETGSLLIENGKIVAAGSEARNQGAPEGAEIVDLDGKAVMPGLVDSRVFIGEPGAEHRETIASASRAAAAGGVTSIIMMPDTDPVIDDVALVEFVKRTARDTAIVNVHPAAAITKGLHGEEMTEFGLLRAAGAVAFTEGRNTIANTQIMRRALTYARDFNAVIACETRDPLLGANGVMNEGLFASWLGLSGTPREAEVIPLERDLRLAALTRSRYHAAQLSCAMSADAMRRAKDLGTNVTAGVSINHLSLNENDIGEFRTFFRLSPPLRGEEDRLAMVEAVKNGTIDIVVSAHDPQDVDTKRLPFSDAEAGAIGLETLLAAALRLYHNDNIPLLRLVEVLSTAPAKIFGLNAGTLKPGASADIAIVDLEEPWVVREEDLHSRSKNSCFESARFQGRVVRTIVAGKTVYSA
Molecule Role Virulence factor
Molecule Role Annotation FUNCTIONAL GROUP: DNA/RNA metabolism, Synthesis (Delrue et al., 2004).

FUNCTION: dihydroorotase (Delrue et al., 2004).

MUTATION: Attenuated in Macrophages, HeLa (Delrue et al., 2004).
COG COG0044F, under F: Nucleotide transport and metabolism
References
Delrue et al., 2004: Delrue RM, Lestrate P, Tibor A, Letesson JJ, De Bolle X. Brucella pathogenesis, genes identified from random large-scale screens. FEMS microbiology letters. 2004; 231(1); 1-12. [PubMed: 14979322].