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fdhA from Brucella melitensis bv. 1 str. 16M

Victor ID 1362
Gene Name fdhA from Brucella melitensis bv. 1 str. 16M
Sequence Strain (Species/Organism) Brucella melitensis bv. 1 str. 16M
NCBI Gene ID 1198150
NCBI Protein GI 17988723
Locus Tag BMEII0378
Protein Accession NP_541356.1
Other Database IDs UniProtKB-ID: Q8YCZ9_BRUME
UniRef100: UniRef100_D0B7W4
UniRef90: UniRef90_D0B7W4
UniRef50: UniRef50_Q3JFC4
UniParc: UPI0000058469
EMBL: AE008918
EMBL-CDS: AAL53620.1
RefSeq_NT: NC_003318.1
GenomeReviews: AE008918_GR
KEGG: bme:BMEII0378
HOGENOM: HBG638124
OMA: FSMVHAS
ProtClustDB: CLSK881521
BioCyc: BMEL224914:BMEII0378-MONOMER
Taxonomy ID 224914
Chromosome No II
Gene Starting Position 393948
Gene Ending Position 396308
Gene Strand (Orientation) +
Protein Name FORMATE DEHYDROGENASE ALPHA CHAIN
DNA Sequence 
>gi|17988344:393948-396308 Brucella melitensis bv. 1 str. 16M chromosome chromosome II, complete sequence
TTTGCTGGCAGGTCATGGCGGCCAGGCATTGTGCTTACAGGATGAAGAGATGAGCAAGGGTAAAAAAACC
GGTTTTATCGGCAAACGTTCCAGCGCGGCAGGCGGATGGGGTGCGCTGAAAAGCTGTGGCCAGCAATTGC
TGGCCAGCGGTGCACCGCTGGCTGGCGCCCGTGCGCTTTTGAAAGCCAATCAGCCGGATGGGTTCGATTG
TCCCGGTTGTGCATGGGGTGATCCCGAACATGGCTCGTCTTTTGAATTTTGTGAAAACGGCGTCAAGGCC
GTTGCCTGGGAGGCAACGGACCGGCGCACTACGCCTGCCTTTTTTCGCGAACACACGGTTTCCAAGCTTC
GGGAATGGACGGATTACGATCTGGAAAATACGGGGCGCCTTACCCATCCCATGCGCTACAACACGGCAAC
GGACAAATATGAAGCCGTTGAATGGGATGAGGCTTTTCAGGCTATCGGCGGCATTCTGAAGAGTTTCGAC
ACGCCCGACCGGGTGGAATTCTATACGTCCGGCCGCGCTTCCAATGAGGCGGCCTTTCTCTACCAGCTTT
TCGTGCGCGCCTATGGCACGAACAATTTTCCCGATTGCTCCAATATGTGCCACGAGGCAAGTGGCGTCGC
GCTGACGCAATCCGTGGGTGTCGGCAAGGGCACGGTGCTGCTGGAGGATTTTGAACAGGCCGATGCGATC
TTCGTTGTAGGGCAAAATCCCGGCACCAATCATCCCCGCATGTTGGGCGATCTGCGCCGCGCGGCGGAGC
GAGGAGCGCGCATCGTAGCCTTCAACCCGGTCCGCGAGCGCGGGCTGGAACGCTTTGCCGACCCGCAGGA
CAAGCTGGAAATGCTGCATGGCGGCAGCGAGCCGATCACGAGCGATTATTTCCAGCCGCGCCTTGGCGGG
GATCTTGCCGCTTTCCGCGGCATGGCGAAGGCCGTGTTCGCTGCCGACGATGCAGCACTTGCTGCCGGAC
GGCCTTCTGTTCTCGACCGGGCGTTTCTGGCTGCGCACACGGCGGAGCTGGAAGCCTACCGGGCTGCGGT
GGATGCGACTTCCTGGGATGAGATCGAGGACCAGTCCGGCCTTCTTCGCCAATCGCTGGAGCGGGCGGCG
GAAATCTATATGCAGGCTGGGCGTGTCATCTGCACCTGGGCGATGGGCATCACGCAGCACCGCCATTCGG
TCATCACGATCCGCGAAATCACCAATTTCATGCTGTTGCGGGGCAATATCGGTAAGCCCGGCGCGGGGCT
CTGCCCGGTGCGCGGCCATTCCAACGTGCAAGGGGACCGGACGGTCGGCATCAACGAGCATCCGCCGGTT
GCGTTTCTCGACGCGCTGGAAAGGGAATTCGGTTTCAAGCCGCCGCGCGAGCCCGGACATAATGTGCTGG
GCGCTATCGGCGCGATGCTGGATGGTACGGCGCAGGCTTTTGTTGCGCTTGGCGGCAATTTCGCCCGTGC
AACACCGGACAGCCCGATCATTTCGAGGGCGCTGTCCAGCCAGCGGTTGACGGTTCATATCGCAACCAAG
CTCAACCATTCACATCTGGTGCCGGGGCGGGATTCTTTCATCCTGCCATGTCTGGGCCGCACTGAAATAG
ACCTCAATTCCAAAGGCGTGGCGCAGATCGTGACGGTGGAGGATTCGATGAGCATGGTGCACGGGTCGGG
TGGCATCAACCAGCCCGCTTCGCCGCTCCTTCGCTCCGAAGTTGCCATTATCGCGGGCATGGCCAATGCC
ACGCTGGGACCAAAGCCCGTGGACTGGCTGGCGCTTGCCGATGATTACGATCTTATCCGCGAGCATATTG
CGCGGGTGCTGCCGGATTTCCACGATTATAATCGCCGTGTGCGGGTGCCGCGCGGGTTTCACCTGCGCAA
TGCTGCCCGCGACCTTGAGTGGAATACGCCAACGGGCAAGGCAACGTTCTGGACCGGTGCCCTGCCGCAA
GCGATCGAGCACCAGCAGGTGCGGGATAAGCCGGGACGTTATGTGCTGCAAACCTTCCGCAGTCACGACC
AGTACAACACCACGATTTATGGCATGAATGACCGTTATCGCGGTGTTTACGGCGAGCGCCATGTGGTCTT
CATGAACCCGCTTGATATGGCCGATCTGGGTGTCGAGGCTGGAGACCGGGCCGATATTGTTGGAGAGTTC
GATGATGGCGTGGAGCGTGTTGCCGCGAATTTCCGTTTCGTGCCTTATGACATTCCGCGCGGCTGCATCG
CTGGCTACTATCCTGAAATGAATGTGCTGGTGCCGCTTGGCAGTGCGGGCGACGAGAGCGACACGCCCAC
GTCCAAATCGATCATTGTATCGTTCCGGCTTAACCGGACAAAGGCTGCATG
Protein Sequence 
>gi|17988723|ref|NP_541356.1| formate dehydrogenase alpha chain [Brucella melitensis bv. 1 str. 16M] MLAGHGGQALCLQDEEMSKGKKTGFIGKRSSAAGGWGALKSCGQQLLASGAPLAGARALLKANQPDGFDCPGCAWGDPEHGSSFEFCENGVKAVAWEATDRRTTPAFFREHTVSKLREWTDYDLENTGRLTHPMRYNTATDKYEAVEWDEAFQAIGGILKSFDTPDRVEFYTSGRASNEAAFLYQLFVRAYGTNNFPDCSNMCHEASGVALTQSVGVGKGTVLLEDFEQADAIFVVGQNPGTNHPRMLGDLRRAAERGARIVAFNPVRERGLERFADPQDKLEMLHGGSEPITSDYFQPRLGGDLAAFRGMAKAVFAADDAALAAGRPSVLDRAFLAAHTAELEAYRAAVDATSWDEIEDQSGLLRQSLERAAEIYMQAGRVICTWAMGITQHRHSVITIREITNFMLLRGNIGKPGAGLCPVRGHSNVQGDRTVGINEHPPVAFLDALEREFGFKPPREPGHNVLGAIGAMLDGTAQAFVALGGNFARATPDSPIISRALSSQRLTVHIATKLNHSHLVPGRDSFILPCLGRTEIDLNSKGVAQIVTVEDSMSMVHGSGGINQPASPLLRSEVAIIAGMANATLGPKPVDWLALADDYDLIREHIARVLPDFHDYNRRVRVPRGFHLRNAARDLEWNTPTGKATFWTGALPQAIEHQQVRDKPGRYVLQTFRSHDQYNTTIYGMNDRYRGVYGERHVVFMNPLDMADLGVEAGDRADIVGEFDDGVERVAANFRFVPYDIPRGCIAGYYPEMNVLVPLGSAGDESDTPTSKSIIVSFRLNRTKAA
Molecule Role Virulence factor
Molecule Role Annotation FUNCTIONAL GROUP: Oxidoreduction (Delrue et al., 2004).

FUNCTION: Formate dehydrogenase (Delrue et al., 2004).

MUTATION: Attenuated in Mice (Delrue et al., 2004).
COG COG0243C, under C: Energy production and conversion
References
Delrue et al., 2004: Delrue RM, Lestrate P, Tibor A, Letesson JJ, De Bolle X. Brucella pathogenesis, genes identified from random large-scale screens. FEMS microbiology letters. 2004; 231(1); 1-12. [PubMed: 14979322].