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flgE from Brucella melitensis bv. 1 str. 16M

Victor ID 1351
Gene Name flgE from Brucella melitensis bv. 1 str. 16M
Sequence Strain (Species/Organism) Brucella melitensis bv. 1 str. 16M
NCBI Gene ID 1197930
NCBI Protein GI 17988503
Locus Tag BMEII0159
Protein Accession NP_541136.1
Other Database IDs UniProtKB-ID: D0B5E7_BRUME
UniRef100: UniRef100_Q8YDL6
UniRef90: UniRef90_O52070
UniRef50: UniRef50_O52070
UniParc: UPI000005838E
EMBL: GG703779
EMBL-CDS: EEW86839.1
RefSeq_NT: NC_003318.1
OMA: GMSAQAN
Taxonomy ID 224914
Chromosome No II
Gene Starting Position 171535
Gene Ending Position 172725
Gene Strand (Orientation) +
Protein Name flagellar hook protein FlgE
DNA Sequence 
>gi|17988344:171535-172725 Brucella melitensis bv. 1 str. 16M chromosome chromosome II, complete sequence
AATGAGCCTCTACGGTATGATGCGGACCGGTGTTTCGGGAATGAATGCTCAGGCGAACCGTTTGTCGACA
GTTGCGGATAATATCGCAAATGCAAGCACGGTCGGTTACAAGCGCGCGGAAACGCAATTCTCCTCGCTTG
TCCTGCCCAGCACTGCCGGACAATATAATTCCGGCAGCGTACTGACCGATGTGCGCTATGGCATTTCCGA
TCAGGGCGGTATTCGTTCCACGTCTTCCACGACCGATCTTGCCATTGATGGCAATGGCTATTTCGTGGTG
CAAGGCCCCGGCGGCTCCACCTATCTGACACGGGCCGGTTCTTTCGTGCCGGACAAGAACGGCGATCTGG
TCAATTCCGCCGGTTATTATCTGCTGGGTGCGGGCGCGGACGAGGCGGCGGGTGGGCTGACCGTCGCGGG
GCTTAATATCGTCAATGTCAACGCGGCCGCTTTGCCGGCAGAGGGAAGCACGGCGGGCGATTTCACCGTC
AACCTGCCTTCCACCGATCAGGCGCCTGCGGCTGGCGGATATAACCACAAAACCTCGCTCATTTCCTATA
ATGACAAGGGTGAGAAGATCACGCTCGACGTCTATTTCACCAAGACGGGTGCGGATGAATGGAATGTTTC
CGTGAAGAACGCTGCCGATGGCGTGGAGATCGGCACGACGGTGCTGAACTTCGATCCCACAACGGGCGAT
CTCGTTTCCGGTGGCAATGTCGCGGTCAATCTCGGTGCCTATGGTGGCCAGACCCTCAATCTCAATCTGG
GCGGTTCCACGCAGCGTGCGGGCGATTACACGATTTCACAGGCGGTCATCAACGGTCAGGCGCCTTCATC
CATCAAGGGTGTGGATGTCGGTAATGACGGTGCGGTGGTCGCGGTCTATGAAAATGGCACGCAGAAGGTT
CTCTACCGTATTCCGCTTGCCAATGTAGCAAGCCCGGACCGCATGACGGTGGTGAGCGGCAACATATTCC
TGCCCAGTGCGGAATCCGGCGATGTCCGCCTTGGCTTCCCGCAGGGCGATGGCATGGGCAAGATCATGTC
CGGCACGCTGGAGGAATCCAATGCCGATATAGCGCAGGAGCTGACCGACATGATCGAGGCGCAGCGCAGC
TATACGGCCAATTCCAAGGTTTTCCAGACGGGTTTCGAGCTGATGGACGTGCTGGTTAATCTGAAGAGAT
A
Protein Sequence 
>gi|17988503|ref|NP_541136.1| flagellar hook protein FlgE [Brucella melitensis bv. 1 str. 16M] MSLYGMMRTGVSGMNAQANRLSTVADNIANASTVGYKRAETQFSSLVLPSTAGQYNSGSVLTDVRYGISDQGGIRSTSSTTDLAIDGNGYFVVQGPGGSTYLTRAGSFVPDKNGDLVNSAGYYLLGAGADEAAGGLTVAGLNIVNVNAAALPAEGSTAGDFTVNLPSTDQAPAAGGYNHKTSLISYNDKGEKITLDVYFTKTGADEWNVSVKNAADGVEIGTTVLNFDPTTGDLVSGGNVAVNLGAYGGQTLNLNLGGSTQRAGDYTISQAVINGQAPSSIKGVDVGNDGAVVAVYENGTQKVLYRIPLANVASPDRMTVVSGNIFLPSAESGDVRLGFPQGDGMGKIMSGTLEESNADIAQELTDMIEAQRSYTANSKVFQTGFELMDVLVNLKR
Molecule Role Virulence factor
Molecule Role Annotation FUNCTIONAL GROUP: "Classical virulence factors", Secretion of transport system, Flagella (Delrue et al., 2004).

FUNCTION: Hook (Delrue et al., 2004).

SIMILARITY: Belongs to the flagella basal body rod proteins family(UniProt: Q8FUS9).

MUTATION: Attenuated in Mice, but not in Macrophages, HeLa (Delrue et al., 2004).
COG COG1749N, under N: Cell motility
References
Delrue et al., 2004: Delrue RM, Lestrate P, Tibor A, Letesson JJ, De Bolle X. Brucella pathogenesis, genes identified from random large-scale screens. FEMS microbiology letters. 2004; 231(1); 1-12. [PubMed: 14979322].