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mce3A from Mycobacterium tuberculosis H37Rv

Victor ID 133
Gene Name mce3A from Mycobacterium tuberculosis H37Rv
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 885944
NCBI Protein GI 57116931
Locus Tag Rv1966
Protein Accession YP_177852.1
Other Database IDs UniProtKB-ID: Q7D7P0_MYCTU
UniRef100: UniRef100_A5U3Y6
UniRef90: UniRef90_A5U3Y6
UniRef50: UniRef50_A4T971
UniParc: UPI000004B718
EMBL: AE000516
EMBL: BX842578
EMBL-CDS: AAK46292.1
EMBL-CDS: CAE55443.1
RefSeq_NT: NC_002755.2
RefSeq_NT: NC_000962.2
EnsemblGenome: EBMYCG00000000504.
EnsemblGenome_TRS: EBMYCT00000000504
EnsemblGenome_PRO: EBMYCP00000000504
EnsemblGenome: EBMYCG00000072660.
EnsemblGenome_TRS: EBMYCT00000072665
EnsemblGenome_PRO: EBMYCP00000070724
GenomeReviews: AE000516_GR
GenomeRev
Taxonomy ID 83332
Gene Starting Position 2209326
Gene Ending Position 2210603
Gene Strand (Orientation) +
Protein Name MCE-FAMILY PROTEIN MCE3A
DNA Sequence 
>gi|57116681:2209326-2210603 Mycobacterium tuberculosis H37Rv, complete genome
CATGAGACGCGGGCCGGGTCGACACCGTTTGCACGACGCGTGGTGGACGCTGATCCTGTTCGCGGTGATC
GGGGTGGCTGTCCTGGTGACGGCGGTGTCCTTCACGGGCAGCTTGCGGTCGACTGTGCCGGTGACGCTGG
CGGCCGACCGCTCCGGGCTGGTGATGGACTCCGGCGCCAAGGTCATGATGCGCGGTGTGCAGGTCGGCCG
GGTCGCCCAGATCGGTCGGATCGAGTGGGCCCAGAACGGGGCGAGCCTCAGACTGGAGATCGACCCCGAC
CAGATCCGGTACATCCCGGCCAATGTCGAGGCACAGATCAGCGCCACCACCGCATTCGGTGCCAAGTTCG
TCGACCTGGTGATGCCGCAAAACCCAAGTCGTGCACGGCTGTCCGCTGGGGCGGTACTGCATTCGAAGAA
CGTCAGCACGGAAATCAACACCGTCTTCGAAAACGTCGTCGACCTGCTCAACATGATCGACCCGCTGAAA
CTGAACGCCGTGCTGACCGCGGTCGCCGACGCCGTTCGCGGGCAAGGTGAACGGATAGGCCAGGCCACCA
CCGACCTCAACGAGGTGCTGGAGGCACTCAACGCACGCGGCGACACCATCGGCGGCAACTGGCGATCGCT
CAAGAACTTCACCGACACCTATGACGCGGCCGCCCAAGACATCCTGACGATCCTGAACGCCGCCAGCACC
ACCAGTGCGACCGTCGTGAATCATTCGACGCAGCTGGATGCCTTGCTACTCAACGCCATCGGACTATCCA
ACGCTGGCACCAACCTGCTTGGCAGCAGCCGAGACAATCTCGTCGGCGCGGCCGACATCCTGGCGCCGAC
CACGAGCCTGCTGTTCAAGTACAACCCCGAATACACCTGCTTCCTGCAGGGCGCCAAGTGGTATCTCGAC
AACGGCGGCTATGCGGCCTGGGGCGGGGCCGACGGGCGCACGCTACAACTCGATGTGGCGCTACTGTTCG
GCAACGACCCCTATGTCTATCCGGACAACCTGCCGGTTGTCGCGGCCAAGGGGGGTCCCGGCGGAAGGCC
GGGATGCGGGCCATTGCCGGATGCCACCCACAACTTCCCGGTGCGCCAGCTGGTCACCAACACCGGATGG
GGAACCGGGCTGGACATCCGGCCCAACCCCGGCATCGGGCATCCCTGCTGGGCCAACTACTTCCCGGTGA
CCCGCGCGGTGCCCGAGCCGCCGTCGATCCGTCAGTGCATCCCCGGGCCGGCGATCGGGCCCAACCCCGC
GGCGGGGGAGCAGCCATG
Protein Sequence 
>gi|57116931|ref|YP_177852.1| Mce family protein Mce3A [Mycobacterium tuberculosis H37Rv] MRRGPGRHRLHDAWWTLILFAVIGVAVLVTAVSFTGSLRSTVPVTLAADRSGLVMDSGAKVMMRGVQVGRVAQIGRIEWAQNGASLRLEIDPDQIRYIPANVEAQISATTAFGAKFVDLVMPQNPSRARLSAGAVLHSKNVSTEINTVFENVVDLLNMIDPLKLNAVLTAVADAVRGQGERIGQATTDLNEVLEALNARGDTIGGNWRSLKNFTDTYDAAAQDILTILNAASTTSATVVNHSTQLDALLLNAIGLSNAGTNLLGSSRDNLVGAADILAPTTSLLFKYNPEYTCFLQGAKWYLDNGGYAAWGGADGRTLQLDVALLFGNDPYVYPDNLPVVAAKGGPGGRPGCGPLPDATHNFPVRQLVTNTGWGTGLDIRPNPGIGHPCWANYFPVTRAVPEPPSIRQCIPGPAIGPNPAAGEQP
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: mce3A mutant is attenuated in mice (Gioffré et al., 2005).
COG COG1463Q, under Q: Secondary metabolites biosynthesis, transport and catabolism
References
Gioffré et al., 2005: Gioffré A, Infante E, Aguilar D, Santangelo MP, Klepp L, Amadio A, Meikle V, Etchechoury I, Romano MI, Cataldi A, Hernández RP, Bigi F. Mutation in mce operons attenuates Mycobacterium tuberculosis virulence. Microbes and infection / Institut Pasteur. 2005; 7(3); 325-334. [PubMed: 15804490].